Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites
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Processing of a complex multiply damaged DNA site by human cell extracts and purified repair proteinsEffects of Charged Particles on Human Tumor CellsComments on potential health effects of MRI-induced DNA lesions: quality is more important to consider than quantityEfficient formation of the tandem thymine glycol/8-oxo-7,8-dihydroguanine lesion in isolated DNA and the mutagenic and cytotoxic properties of the tandem lesions in Escherichia coli cells.Molecular analysis of base damage clustering associated with a site-specific radiation-induced DNA double-strand break.A stochastic model of DNA fragments rejoiningDelayed repair of radiation induced clustered DNA damage: friend or foe?Irreparable complex DNA double-strand breaks induce chromosome breakage in organotypic three-dimensional human lung epithelial cell cultureInterplay between DNA N-glycosylases/AP lyases at multiply damaged sites and biological consequences.Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation.Efficient cleavage of single and clustered AP site lesions within mono-nucleosome templates by CHO-K1 nuclear extract contrasts with retardation of incision by purified APE1.Base excision repair processing of abasic site/single-strand break lesions within clustered damage sites associated with XRCC1 deficiency.Non-problematic risks from low-dose radiation-induced DNA damage clustersThe formation of double-strand breaks at multiply damaged sites is driven by the kinetics of excision/incision at base damage in eukaryotic cells.Replication fork collapse is a major cause of the high mutation frequency at three-base lesion clustersThe yield, processing, and biological consequences of clustered DNA damage induced by ionizing radiation.In vitro replication and repair studies of tandem lesions containing neighboring thymidine glycol and 8-oxo-7,8-dihydro-2'-deoxyguanosineA genomic perspective to assessing quality of mass-reared SIT flies used in Mediterranean fruit fly (Ceratitis capitata) eradication in California.Processing of bistranded abasic DNA clusters in gamma-irradiated human hematopoietic cells.Reduced repair capacity of a DNA clustered damage site comprised of 8-oxo-7,8-dihydro-2'-deoxyguanosine and 2-deoxyribonolactone results in an increased mutagenic potential of these lesions.Ionising radiation and genetic risks. XVI. A genome-based framework for risk estimation in the light of recent advances in genome research.Relatively high rates of G:C → A:T transitions at CpG sites were observed in certain epithelial tissues including pancreas and submaxillary gland of adult big blue® mice.The role of SOG1, a plant-specific transcriptional regulator, in the DNA damage response.Excess processing of oxidative damaged bases causes hypersensitivity to oxidative stress and low dose rate irradiation.Increased mutability and decreased repairability of a three-lesion clustered DNA-damaged site comprised of an AP site and bi-stranded 8-oxoG lesions.Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage.RBE of α-particles from (211)At for complex DNA damage and cell survival in relation to cell cycle position.Repair of clustered uracil DNA damages in Escherichia coli.Induction and repairability of DNA damage caused by ultrasoft X-rays: role of core events.The platelets' perspective to pathogen reduction technologies.Induction and quantification of gamma-H2AX foci following low and high LET-irradiation.Two clustered 8-oxo-7,8-dihydroguanine (8-oxodG) lesions increase the point mutation frequency of 8-oxodG, but do not result in double strand breaks or deletions in Escherichia coli.Isolation of chromatin from dysfunctional telomeres reveals an important role for Ring1b in NHEJ-mediated chromosome fusionsEnhanced mutagenic potential of 8-oxo-7,8-dihydroguanine when present within a clustered DNA damage siteProcessing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation.Proton-induced direct and indirect damage of plasmid DNA.Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic.The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage.Radioprotective properties of Hippophae rhamnoides (sea buckthorn) extract in vitroClustered abasic lesions profoundly change the structure and stability of human telomeric G-quadruplexes.
P2860
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P2860
Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites
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2002 nî lūn-bûn
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2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2002 թվականի օգոստոսին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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Clustered DNA damage induced b ...... as Fpg and Nth sensitive sites
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Clustered DNA damage induced b ...... as Fpg and Nth sensitive sites
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Clustered DNA damage induced b ...... as Fpg and Nth sensitive sites
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Clustered DNA damage induced b ...... as Fpg and Nth sensitive sites
@ast
Clustered DNA damage induced b ...... as Fpg and Nth sensitive sites
@en
Clustered DNA damage induced b ...... as Fpg and Nth sensitive sites
@nl
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Clustered DNA damage induced b ...... as Fpg and Nth sensitive sites
@ast
Clustered DNA damage induced b ...... as Fpg and Nth sensitive sites
@en
Clustered DNA damage induced b ...... as Fpg and Nth sensitive sites
@nl
P2093
P2860
P356
P1476
Clustered DNA damage induced b ...... as Fpg and Nth sensitive sites
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P2093
Catherine de Lara
Jonathan Fulford
Melanie Gulston
Peter O'Neill
Terry Jenner
P2860
P304
P356
10.1093/NAR/GKF467
P407
P577
2002-08-01T00:00:00Z