BET bromodomain inhibition suppresses TH17-mediated pathology. - Wikidata - wikimedia - TriplyDB

BET bromodomain inhibition suppresses TH17-mediated pathology.

BET bromodomain inhibition suppresses TH17-mediated pathology.

http://www.wikidata.org/entity/Q34375887

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Immune Cells and Inflammation in Diabetic Nephropathy The Interplay Between Monocytes/Macrophages and CD4(+) T Cell Subsets in Rheumatoid Arthritis The bromodomain: from epigenome reader to druggable target Epigenetic polypharmacology: from combination therapy to multitargeted drugs Histone Posttranslational Modifications of CD4⁺ T Cell in Autoimmune Diseases The mechanisms behind the therapeutic activity of BET bromodomain inhibition Functions of BET proteins in erythroid gene expression Bromodomains: Translating the words of lysine acetylation into myelin injury and repair Segmental Isotope Labelling of an Individual Bromodomain of a Tandem Domain BRD4 Using Sortase A BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models BET bromodomain proteins and epigenetic regulation of inflammation: implications for type 2 diabetes and breast cancer.Comparative Safety and Efficacy Profile of a Novel Oil in Water Vaccine Adjuvant Comprising Vitamins A and E and a Catechin in Protective Anti-Influenza Immunity.Chemical probes targeting epigenetic proteins: Applications beyond oncology.High CTLA-4 expression on Th17 cells results in increased sensitivity to CTLA-4 coinhibition and resistance to belatacept In search of magic bullets: the golden age of immunotherapeutics.Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes.Transcriptional and epigenetic regulation of T-helper lineage specification.Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells.Transcriptional and epigenetic networks of helper T and innate lymphoid cells.Inhibiting STAT5 by the BET bromodomain inhibitor JQ1 disrupts human dendritic cell maturation.Small-molecule control of cytokine function: new opportunities for treating immune disorders BET bromodomain inhibition suppresses graft-versus-host disease after allogeneic bone marrow transplantation in mice.CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET High-density P300 enhancers control cell state transitions.CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses RORγt+ cells selectively express redundant cation channels linked to the Golgi apparatus BET Inhibition Attenuates Helicobacter pylori-Induced Inflammatory Response by Suppressing Inflammatory Gene Transcription and Enhancer Activation.Chromatin Landscape of the IRF Genes and Role of the Epigenetic Reader BRD4.Antiinflammatory effects of bromodomain and extraterminal domain inhibition in cystic fibrosis lung inflammation The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease Clinical trials for BET inhibitors run ahead of the science.Erythropoiesis provides a BRD's eye view of BET protein function.Genetic architecture differences between pediatric and adult-onset inflammatory bowel diseases in the Polish population.Bromodomain and Extra-Terminal Protein Inhibition Attenuates Neutrophil-dominant Allergic Airway Disease.MYC in Regulating Immunity: Metabolism and Beyond.Epigenetic pathway targets for the treatment of disease: accelerating progress in the development of pharmacological tools: IUPHAR Review 11.Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes.Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains BET Proteins: An Approach to Future Therapies in Transplantation.Epigenetic Regulation of Monocyte and Macrophage Function.

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BET bromodomain inhibition suppresses TH17-mediated pathology.

http://www.wikidata.org/entity/Q34375887

description

2013 nî lūn-bûn

@nan

2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

BET bromodomain inhibition suppresses TH17-mediated pathology.

@ast

BET bromodomain inhibition suppresses TH17-mediated pathology.

@en

BET bromodomain inhibition suppresses TH17-mediated pathology.

@nl

type

label

BET bromodomain inhibition suppresses TH17-mediated pathology.

@ast

BET bromodomain inhibition suppresses TH17-mediated pathology.

@en

BET bromodomain inhibition suppresses TH17-mediated pathology.

@nl

prefLabel

BET bromodomain inhibition suppresses TH17-mediated pathology.

@ast

BET bromodomain inhibition suppresses TH17-mediated pathology.

@en

BET bromodomain inhibition suppresses TH17-mediated pathology.

@nl

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P1433

Journal of Experimental Medicine

P1476

BET bromodomain inhibition suppresses TH17-mediated pathology.

@en

P2093

Andres Salmeron

http://www.w3.org/2001/XMLSchema#string

Barbara M Bryant

http://www.w3.org/2001/XMLSchema#string

Deanna A Mele

http://www.w3.org/2001/XMLSchema#string

Hon-Ren Huang

http://www.w3.org/2001/XMLSchema#string

Jose M Lora

http://www.w3.org/2001/XMLSchema#string

Srimoyee Ghosh

http://www.w3.org/2001/XMLSchema#string

P2860

Selective inhibition of BET bromodomains

The AP-1 transcription factor Batf controls T(H)17 differentiation

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

Suppression of inflammation by a synthetic histone mimic

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

Th17 and regulatory T cells in mediating and restraining inflammation.

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

IL-17 and Th17 Cells

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

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2181-2190

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scholarly article

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10.1084/JEM.20130376

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11

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210

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2013-10-07T00:00:00Z

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257531148

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24101376

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3804955

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