A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.
about
A secretory kinase complex regulates extracellular protein phosphorylationInsights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKLHuman TRIB2 Oscillates during the Cell Cycle and Promotes Ubiquitination and Degradation of CDC25CcAMP-dependent protein kinase (PKA) complexes probed by complementary differential scanning fluorimetry and ion mobility-mass spectrometryThe Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent mannerPseudokinases: update on their functions and evaluation as new drug targets.Enhanced interaction between pseudokinase and kinase domains in Gcn2 stimulates eIF2α phosphorylation in starved cellsStructure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-bindingMechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analysesThe molecular regulation of Janus kinase (JAK) activationActivation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death.The evolving world of pseudoenzymes: proteins, prejudice and zombiesTribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease.Bio-Zombie: the rise of pseudoenzymes in biology.Interaction between the tRNA-binding and C-terminal domains of Yeast Gcn2 regulates kinase activity in vivo.ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activationMolecular insights into regulation of JAK2 in myeloproliferative neoplasmsPEAK1 Acts as a Molecular Switch to Regulate Context-Dependent TGFβ Responses in Breast Cancer.Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulationRole of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1.The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signaling.The structure of Legionella pneumophila LegK4 type four secretion system (T4SS) effector reveals a novel dimeric eukaryotic-like kinase.Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2).Targeting ROR1 identifies new treatment strategies in hematological cancers.Structural Basis for the Non-catalytic Functions of Protein Kinases.Flicking the molecular switch underlying MLKL-mediated necroptosis.Evolutionary divergence of the necroptosis effector MLKL.The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitisFrom the research laboratory to the database: the Caenorhabditis elegans kinome in UniProtKBCatalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells.Ars Moriendi; the art of dying well - new insights into the molecular pathways of necroptotic cell death.Kinases and pseudokinases: lessons from RAF.Going for broke: targeting the human cancer pseudokinome.Receptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy.KinView: a visual comparative sequence analysis tool for integrated kinome research.A tale of two domains - a structural perspective of the pseudokinase, MLKL.Nucleotide-binding mechanisms in pseudokinases.DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis.Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 PseudokinasesPost-translational control of RIPK3 and MLKL mediated necroptotic cell death.
P2860
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P2860
A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A robust methodology to subcla ...... nucleotide-binding properties.
@ast
A robust methodology to subcla ...... nucleotide-binding properties.
@en
A robust methodology to subcla ...... nucleotide-binding properties.
@nl
type
label
A robust methodology to subcla ...... nucleotide-binding properties.
@ast
A robust methodology to subcla ...... nucleotide-binding properties.
@en
A robust methodology to subcla ...... nucleotide-binding properties.
@nl
prefLabel
A robust methodology to subcla ...... nucleotide-binding properties.
@ast
A robust methodology to subcla ...... nucleotide-binding properties.
@en
A robust methodology to subcla ...... nucleotide-binding properties.
@nl
P2093
P2860
P50
P356
P1433
P1476
A robust methodology to subcla ...... nucleotide-binding properties.
@en
P2093
Anne Tripaydonis
Christine L Gee
Fiona P Bailey
Isabelle S Lucet
Kelan Chen
Koichi Fukuda
Leila N Varghese
Mary Beth Mudgett
Michael L Reese
P2860
P304
P356
10.1042/BJ20131174
P407
P577
2014-01-01T00:00:00Z