Delineating the genetic basis of systemic lupus erythematosus.
about
A diverse array of genetic factors contribute to the pathogenesis of systemic lupus erythematosusMultiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2I-PLA(2) activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activationSpontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted miceAcceleration of autoimmunity by organochlorine pesticides in (NZB x NZW)F1 mice.Linking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosusSomatic mutagenesis in autoimmunityCrystal structure determination of anti-DNA Fab A52Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupusAnalysis of interleukin-23 receptor (IL23R) gene polymorphisms in systemic lupus erythematosusGenetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosusSLAMF6-driven co-stimulation of human peripheral T cells is defective in SLE T cellsA dinucleotide deletion in CD24 confers protection against autoimmune diseasesA lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigenGenetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) miceMechanisms of Natural Tolerance in the IntestineInterferon and granulopoiesis signatures in systemic lupus erythematosus bloodBreaking tolerance to double stranded DNA, nucleosome, and other nuclear antigens is not required for the pathogenesis of lupus glomerulonephritis.Development of murine lupus involves the combined genetic contribution of the SLAM and FcgammaR intervals within the Nba2 autoimmune susceptibility locus.Lupus glomerulonephritis revisited 2004: autoimmunity and end-organ damage.Auto-antibody production and glomerulonephritis in congenic Slamf1-/- and Slamf2-/- [B6.129] but not in Slamf1-/- and Slamf2-/- [BALB/c.129] mice.Association study of genetic variants of pro-inflammatory chemokine and cytokine genes in systemic lupus erythematosusIdentification of two independent risk factors for lupus within the MHC in United Kingdom families.FcγRIIB and autoimmunity.Genomic organization of classical human low-affinity Fcgamma receptor genes.Was it there all the time?Familiality and co-occurrence of clinical features of systemic lupus erythematosus.Association of the BANK 1 R61H variant with systemic lupus erythematosus in Americans of European and African ancestry.Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus.B cell abnormalities in systemic lupus erythematosusMeta-analysis of programmed cell death 1 polymorphisms with systemic lupus erythematosus riskType I interferons produced by resident renal cells may promote end-organ disease in autoantibody-mediated glomerulonephritis.The lupus susceptibility locus Sle1 breaches peripheral B cell tolerance at the antibody-forming cell and germinal center checkpointsA stop codon polymorphism of Toll-like receptor 5 is associated with resistance to systemic lupus erythematosus.Dendritic cells in systemic lupus erythematosusSpontaneous lupus-like syndrome in HLA-DQ2 transgenic mice with a mixed genetic background.Murine lupus susceptibility locus Sle1a requires the expression of two sub-loci to induce inflammatory T cellsTLR tolerance reduces IFN-alpha production despite plasmacytoid dendritic cell expansion and anti-nuclear antibodies in NZB bicongenic mice.Yaa autoimmune phenotypes are conferred by overexpression of TLR7.
P2860
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P2860
Delineating the genetic basis of systemic lupus erythematosus.
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Delineating the genetic basis of systemic lupus erythematosus.
@ast
Delineating the genetic basis of systemic lupus erythematosus.
@en
Delineating the genetic basis of systemic lupus erythematosus.
@nl
type
label
Delineating the genetic basis of systemic lupus erythematosus.
@ast
Delineating the genetic basis of systemic lupus erythematosus.
@en
Delineating the genetic basis of systemic lupus erythematosus.
@nl
prefLabel
Delineating the genetic basis of systemic lupus erythematosus.
@ast
Delineating the genetic basis of systemic lupus erythematosus.
@en
Delineating the genetic basis of systemic lupus erythematosus.
@nl
P2093
P1433
P1476
Delineating the genetic basis of systemic lupus erythematosus.
@en
P2093
P304
P356
10.1016/S1074-7613(01)00201-1
P407
P577
2001-09-01T00:00:00Z