XAF1 expression is significantly reduced in human melanoma.
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Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-betaNuclear ING2 expression is reduced in human cutaneous melanomasDown-regulation of the pro-apoptotic XIAP associated factor-1 (XAF1) during progression of clear-cell renal cancer.Tumor suppressor XAF1 induces apoptosis, inhibits angiogenesis and inhibits tumor growth in hepatocellular carcinoma.Domain organization of XAF1 and the identification and characterization of XIAP(RING) -binding domain of XAF1.XAF1 directs apoptotic switch of p53 signaling through activation of HIPK2 and ZNF313XAF1 expression and regulatory effects of somatostatin on XAF1 in prostate cancer cells.Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: implication for attenuated p53 response to apoptotic stresses.Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex.XAF1 is frequently methylated in human esophageal cancerEpigenetic silencing of the XAF1 gene is mediated by the loss of CTCF binding.High LIFr expression stimulates melanoma cell migration and is associated with unfavorable prognosis in melanoma.Augmentation of effects of interferon-stimulated genes by reversal of epigenetic silencing: potential application to melanoma.Inhibitor of apoptosis proteins as targets for anticancer therapy.Inhibitor of apoptosis proteins in hematological malignancies.XAF1 promotes neuroblastoma tumor suppression and is required for KIF1Bβ-mediated apoptosisEpigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome.Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities.Immunohistochemical detection of XIAP in melanoma.Key regulators of apoptosis execution as biomarker candidates in melanomaNetwork analysis of icb-1 gene function in human breast cancer cells.NF-κB inducing kinase (NIK) modulates melanoma tumorigenesis by regulating expression of pro-survival factors through the β-catenin pathway.The tumor suppressor ING3 is degraded by SCF(Skp2)-mediated ubiquitin-proteasome system.Reversal of methylation silencing of Apo2L/TRAIL receptor 1 (DR4) expression overcomes resistance of SK-MEL-3 and SK-MEL-28 melanoma cells to interferons (IFNs) or Apo2L/TRAIL.Potent antitumor efficacy of XAF1 delivered by conditionally replicative adenovirus vector via caspase-independent apoptosis.The future of dermatopathology.Assessment of XAF1 as A Biomarker to Differentiate Hepatocellular Carcinoma from Nonneoplastic Liver Tissues.Synergistic suppression effect on tumor growth of hepatocellular carcinoma by combining oncolytic adenovirus carrying XAF1 with cisplatin.Identification of XAF1-MT2A mutual antagonism as a molecular switch in cell-fate decisions under stressful conditions.Deconvolution of heterogeneous wound tissue samples into relative macrophage phenotype composition via models based on gene expression.Targeting the intrinsic apoptosis pathway as a strategy for melanoma therapy.XAF1 mediates tumor necrosis factor-alpha-induced apoptosis and X-linked inhibitor of apoptosis cleavage by acting through the mitochondrial pathway.
P2860
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P2860
XAF1 expression is significantly reduced in human melanoma.
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
name
XAF1 expression is significantly reduced in human melanoma.
@ast
XAF1 expression is significantly reduced in human melanoma.
@en
XAF1 expression is significantly reduced in human melanoma.
@nl
type
label
XAF1 expression is significantly reduced in human melanoma.
@ast
XAF1 expression is significantly reduced in human melanoma.
@en
XAF1 expression is significantly reduced in human melanoma.
@nl
prefLabel
XAF1 expression is significantly reduced in human melanoma.
@ast
XAF1 expression is significantly reduced in human melanoma.
@en
XAF1 expression is significantly reduced in human melanoma.
@nl
P2093
P1476
XAF1 expression is significantly reduced in human melanoma.
@en
P2093
Kin Cheung P Ng
Magdalena Martinka
P304
P356
10.1111/J.0022-202X.2004.23467.X
P407
P577
2004-12-01T00:00:00Z
P5875
P6179
1044497255