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Cyclopeptide Smac mimetics as antagonists of IAP proteins.

Cyclopeptide Smac mimetics as antagonists of IAP proteins.

http://www.wikidata.org/entity/Q34382271

about

Biological evaluation of new largazole analogues: alteration of macrocyclic scaffold with click chemistry.Small-molecule IAP antagonists sensitize cancer cells to TRAIL-induced apoptosis: roles of XIAP and cIAPs.Apoptosis in cancer: from pathogenesis to treatment.Design, synthesis and evaluation of inhibitor of apoptosis protein (IAP) antagonists that are highly selective for the BIR2 domain of XIAP.Design, synthesis and evaluation of monovalent Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP.Synthesis of sansalvamide A peptidomimetics: triazole, oxazole, thiazole, and pseudoproline containing compounds.Dimeric Macrocyclic Antagonists of Inhibitor of Apoptosis Proteins for the Treatment of Cancer.Inhibitors of apoptosis: clinical implications in cancer.

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P2860

Cyclopeptide Smac mimetics as antagonists of IAP proteins.

http://www.wikidata.org/entity/Q34382271

description

2010 nî lūn-bûn

@nan

2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Cyclopeptide Smac mimetics as antagonists of IAP proteins.

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Cyclopeptide Smac mimetics as antagonists of IAP proteins.

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Cyclopeptide Smac mimetics as antagonists of IAP proteins.

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type

label

Cyclopeptide Smac mimetics as antagonists of IAP proteins.

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Cyclopeptide Smac mimetics as antagonists of IAP proteins.

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Cyclopeptide Smac mimetics as antagonists of IAP proteins.

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prefLabel

Cyclopeptide Smac mimetics as antagonists of IAP proteins.

@ast

Cyclopeptide Smac mimetics as antagonists of IAP proteins.

@en

Cyclopeptide Smac mimetics as antagonists of IAP proteins.

@nl

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J.BMCL.2010.03.114

P1433

Bioorganic & Medicinal Chemistry Letters

P1476

Cyclopeptide Smac mimetics as antagonists of IAP proteins.

@en

P2093

Chao-Yie Yang

http://www.w3.org/2001/XMLSchema#string

Haiying Sun

http://www.w3.org/2001/XMLSchema#string

Han Yi

http://www.w3.org/2001/XMLSchema#string

Jianfeng Lu

http://www.w3.org/2001/XMLSchema#string

Liu Liu

http://www.w3.org/2001/XMLSchema#string

Shaomeng Wang

http://www.w3.org/2001/XMLSchema#string

Su Qiu

http://www.w3.org/2001/XMLSchema#string

P2860

Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain

Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases

Mechanism of XIAP-mediated inhibition of caspase-9

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

Structural basis of IAP recognition by Smac/DIABLO

Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs

Interaction of a Cyclic, Bivalent Smac Mimetic with the X-Linked Inhibitor of Apoptosis Protein † ‡

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3043-3046

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scholarly article

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20443226

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2997469

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