Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL.
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CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target geneCombating the epigenome: epigenetic drugs against non-Hodgkin's lymphomaSWI/SNF chromatin remodeling complexes and cancerUsing mouse models to study function of transcriptional factors in T cell developmentRole of the transcription factor Bcl11b in development and lymphomagenesisCoordinated regulation of transcription factor Bcl11b activity in thymocytes by the mitogen-activated protein kinase (MAPK) pathways and protein sumoylation.CTIP2 expression in human head and neck squamous cell carcinoma is linked to poorly differentiated tumor status.Bcl11b mutations identified in murine lymphomas increase the proliferation rate of hematopoietic progenitor cells.Increased expression of bcl11b leads to chemoresistance accompanied by G1 accumulation.Down regulation of BCL11B expression inhibits proliferation and induces apoptosis in malignant T cells by BCL11B-935-siRNA.ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification.Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemiaLow expression of T-cell transcription factor BCL11b predicts inferior survival in adult standard risk T-cell acute lymphoblastic leukemia patientsReduced level of the BCL11B protein is associated with adult T-cell leukemia/lymphoma.Gene expression profiles in BCL11B-siRNA treated malignant T cells.Genome-wide analyses identify KLF4 as an important negative regulator in T-cell acute lymphoblastic leukemia through directly inhibiting T-cell associated genes.Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells.Analysis of the expression of PHTF1 and related genes in acute lymphoblastic leukemiaThe role of BCL11B in hematological malignancyThe complex translocation (9;14;14) involving IGH and CEBPE genes suggests a new subgroup in B-lineage acute lymphoblastic leukemia.The evolution of malignant and reactive γδ + T cell clones in a relapse T-ALL case after allogeneic stem cell transplantation.The TCR γδ repertoire and relative gene expression characteristics of T-ALL cases with biclonal malignant Vδ1 and Vδ2 T cells.T-cell acute lymphoblastic leukaemia: recent molecular biology findings.Breakpoint sites disclose the role of the V(D)J recombination machinery in the formation of T-cell receptor (TCR) and non-TCR associated aberrations in T-cell acute lymphoblastic leukemia.Genomic characterization of acute leukemias.Pediatric T-cell acute lymphoblastic leukemia.Gross deletions involving IGHM, BTK, or Artemis: a model for genomic lesions mediated by transposable elements.Integrated genome-wide genotyping and gene expression profiling reveals BCL11B as a putative oncogene in acute myeloid leukemia with 14q32 aberrations.BCL11B suppression does not influence CD34(+) cell differentiation and proliferation.Inhibition of BCL11B expression leads to apoptosis of malignant but not normal mature T cells.Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes.Characterization of a pediatric T-cell acute lymphoblastic leukemia patient with simultaneous LYL1 and LMO2 rearrangements.Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes.Tcrδ translocations that delete the Bcl11b haploinsufficient tumor suppressor gene promote atm-deficient T cell acute lymphoblastic leukemia.An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b.Comprehensive translocation and clonality detection in lymphoproliferative disorders by next-generation sequencing.The N-terminal CCHC zinc finger motif mediates homodimerization of the transcription factor BCL11B.Depletion of B cell CLL/Lymphoma 11B Gene Expression Represses Glioma Cell Growth.Bcl11b prevents the intrathymic development of innate CD8 T cells in a cell intrinsic manner.Different genetic alteration of A20 in a Sézary syndrome case with Vα2-Jα22 T cell clone.
P2860
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P2860
Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL.
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Disruption of the BCL11B gene through inv
@nl
Disruption of the BCL11B gene ...... e BCL11B transcripts in T-ALL.
@ast
Disruption of the BCL11B gene ...... e BCL11B transcripts in T-ALL.
@en
type
label
Disruption of the BCL11B gene through inv
@nl
Disruption of the BCL11B gene ...... e BCL11B transcripts in T-ALL.
@ast
Disruption of the BCL11B gene ...... e BCL11B transcripts in T-ALL.
@en
prefLabel
Disruption of the BCL11B gene through inv
@nl
Disruption of the BCL11B gene ...... e BCL11B transcripts in T-ALL.
@ast
Disruption of the BCL11B gene ...... e BCL11B transcripts in T-ALL.
@en
P2093
P2860
P356
P1433
P1476
Disruption of the BCL11B gene ...... pe BCL11B transcripts in T-ALL
@en
P2093
Grabarczyk P
Langerak AW
Przybylski GK
Schmidt CA
P2860
P2888
P304
P356
10.1038/SJ.LEU.2403619
P577
2005-02-01T00:00:00Z
P5875
P6179
1039627593