Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance.
about
Role of ENPP1 on adipocyte maturationObesity genetics in mouse and human: back and forth, and back againCrystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signalingMechanisms of disease: Ectonucleotide pyrophosphatase phosphodiesterase 1 as a 'gatekeeper' of insulin receptorsPHEX mimetic (SPR4-peptide) corrects and improves HYP and wild type mice energy-metabolismENPP1 affects insulin action and secretion: evidences from in vitro studies.Genomic insights into early-onset obesity.Altered bone development and an increase in FGF-23 expression in Enpp1(-/-) mice.A role of apolipoprotein D in triglyceride metabolismPhysiologic and pathologic functions of the NPP nucleotide pyrophosphatase/phosphodiesterase family focusing on NPP1 in calcificationLiver ENPP1 protein increases with remission of type 2 diabetes after gastric bypass surgery.Characterization of monoclonal antibodies to the plasma cell alloantigen ENPP1.Molecular basis of obesity: current status and future prospectsInsulin resistance induced by hyperinsulinemia coincides with a persistent alteration at the insulin receptor tyrosine kinase domain.ENPP1 K121Q polymorphism is not related to type 2 diabetes mellitus, features of metabolic syndrome, and diabetic cardiovascular complications in a Chinese populationGender differences in the relationship of ENPP1/PC-1 variants to obesity in a Turkish population.The role of membrane glycoprotein plasma cell antigen 1/ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities.Treating insulin resistance: future prospects.The role of HSP70 on ENPP1 expression and insulin-receptor activation.Genetic risk factors for type 2 diabetes with pharmacologic intervention in African-American patients with schizophrenia or schizoaffective disorder.Ectonucleotide pyrophosphatase/phosphodiesterase activity in Neuro-2a neuroblastoma cells: changes in expression associated with neuronal differentiation.Cognitive deficits associated with a high-fat diet and insulin resistance are potentiated by overexpression of ecto-nucleotide pyrophosphatase phosphodiesterase-1.Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.Inorganic pyrophosphatase induces type I collagen in osteoblasts.Adipose Tissue Insulin Resistance in Gestational Diabetes.The hepatic ectonucleotide pyrophosphatase/phosphodiesterase 1 gene mRNA abundance is reduced by insulin and induced by dexamethasone.The ENPP1 K121Q polymorphism is not associated with type 2 diabetes in northern Chinese.Uric Acid Impairs Insulin Signaling by Promoting Enpp1 Binding to Insulin Receptor in Human Umbilical Vein Endothelial Cells.
P2860
Q24293330-07EA634D-EFA5-4225-8B49-A48FBAFC47D2Q26782027-A299D5CA-7145-40EE-A889-9382B68D3F02Q27673871-78310AFF-9D81-4280-973D-DA7BC43E2893Q28277019-82AFCB7F-010B-4400-9C02-6ED32FB68E71Q31161423-90B9BD2D-DB55-4BB7-89FF-8DF45B06BE37Q33900871-BE3A448B-AF9D-4738-AAB4-5EFF360C543FQ33999488-FCDDDA90-A3EE-47FB-AF8B-2122A0EBE843Q34168605-3212B51C-0FA4-49BE-AAA0-B05DD8986F57Q34559829-62AAE938-8903-47D7-A191-B48ECD6371E3Q34769231-6692C6CD-B60B-408C-B665-4E29D2A59442Q34976107-5E95DC45-11BB-49BD-AC40-AFDE4CC24FCCQ35057746-4ECD38ED-AB5D-424D-8C03-19E1CA7B8A06Q35107257-B5898936-0178-4454-A170-DC34575156D3Q35279453-114D205E-E70A-4A7F-8F8B-425B432BF321Q35612753-C3149A36-F11C-44A9-A8C9-8A72C17ACBDBQ35801332-AD7E0144-F740-482F-BB57-38526753C37AQ36463221-A5EB5606-E4A2-4582-A257-A950F97DE5D1Q36806514-0D697B15-D209-4E33-81F4-FA2912131304Q37140562-5F7C3781-B408-4912-B737-FF8F379DACB0Q37365437-5BAEC006-2282-4EAB-A5EB-6E50BE2DD9BFQ38982796-A1883777-0AD4-43B5-9984-70044E8E6EE3Q39217509-692E2303-5E4F-4EEE-804F-FCB995193F5BQ41126480-C8537C85-B9E1-4793-97EB-35B8B5D26531Q41869796-C1013494-EF17-47C7-BF06-3EC914153AA4Q51196334-B259463C-99A7-4FB3-A0C2-4F69697AA7EEQ51245857-3515B2BE-8DF3-4600-9606-B689427F79B8Q51806704-CAA71FE9-F74D-4E72-AC35-21AA11BD91D0Q52606175-5D9D5194-F2B8-494F-A4B7-5E1539C879EA
P2860
Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance.
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Increased hepatic levels of th ...... tance and glucose intolerance.
@ast
Increased hepatic levels of th ...... tance and glucose intolerance.
@en
Increased hepatic levels of th ...... tance and glucose intolerance.
@nl
type
label
Increased hepatic levels of th ...... tance and glucose intolerance.
@ast
Increased hepatic levels of th ...... tance and glucose intolerance.
@en
Increased hepatic levels of th ...... tance and glucose intolerance.
@nl
prefLabel
Increased hepatic levels of th ...... tance and glucose intolerance.
@ast
Increased hepatic levels of th ...... tance and glucose intolerance.
@en
Increased hepatic levels of th ...... tance and glucose intolerance.
@nl
P2093
P50
P1433
P1476
Increased hepatic levels of th ...... stance and glucose intolerance
@en
P2093
Betty A Maddux
Domenico Accili
Ira D Goldfine
Jack F Youngren
Marcia Meseck
Robert Terkeltaub
P304
P356
10.2337/DIABETES.54.2.367
P407
P577
2005-02-01T00:00:00Z