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PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcificationInterleukin-1 induces pro-mineralizing activity of cartilage tissue transglutaminase and factor XIIIaOsteopontin is required for the early onset of high fat diet-induced insulin resistance in miceTissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralizationA stem cell-based approach to cartilage repair.Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance.Inflammation-induced chondrocyte hypertrophy is driven by receptor for advanced glycation end products.Transglutaminase 2 is a marker of chondrocyte hypertrophy and osteoarthritis severity in the Hartley guinea pig model of knee OA.Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleotide pyrophosphatase phosphodiesterase 1 double-deficient mice.Up-regulated expression of the CXCR2 ligand KC/GRO-alpha in atherosclerotic lesions plays a central role in macrophage accumulation and lesion progression.Inorganic pyrophosphate (PPI) in pathologic calcification of articular cartilage.Invited review: the mitochondrion in osteoarthritis.Vanin-1 pantetheinase drives increased chondrogenic potential of mesenchymal precursors in ank/ank miceTransglutaminase 2 is central to induction of the arterial calcification program by smooth muscle cellsRational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant.Association of sporadic chondrocalcinosis with a -4-basepair G-to-A transition in the 5'-untranslated region of ANKH that promotes enhanced expression of ANKH protein and excess generation of extracellular inorganic pyrophosphate.Matrix vesicle plasma cell membrane glycoprotein-1 regulates mineralization by murine osteoblastic MC3T3 cells.Factor XIIIA mobilizes transglutaminase 2 to induce chondrocyte hypertrophic differentiation.Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs.Elevated skeletal osteopontin levels contribute to the hypophosphatasia phenotype in Akp2(-/-) mice.Chondrogenesis mediated by PPi depletion promotes spontaneous aortic calcification in NPP1-/- mice.Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils.IL-8/CXCL8 and growth-related oncogene alpha/CXCL1 induce chondrocyte hypertrophic differentiation.The tetrabasic KKKK(147-150) motif determines intracrine regulatory effects of PthrP 1-173 on chondrocyte PPi metabolism and matrix synthesis.Upregulated ank expression in osteoarthritis can promote both chondrocyte MMP-13 expression and calcification via chondrocyte extracellular PPi excess.Decarboxylative borylation.Chondrocyte calcium-sensing receptor expression is up-regulated in early guinea pig knee osteoarthritis and modulates PTHrP, MMP-13, and TIMP-3 expression.Parathyroid hormone-related proteins is abundant in osteoarthritic cartilage, and the parathyroid hormone-related protein 1-173 isoform is selectively induced by transforming growth factor beta in articular chondrocytes and suppresses generation of
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description
hulumtuese
@sq
onderzoeker
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researcher
@en
հետազոտող
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name
Kristen Johnson
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Kristen Johnson
@en
Kristen Johnson
@es
Kristen Johnson
@nl
Kristen Johnson
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type
label
Kristen Johnson
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Kristen Johnson
@en
Kristen Johnson
@es
Kristen Johnson
@nl
Kristen Johnson
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prefLabel
Kristen Johnson
@ast
Kristen Johnson
@en
Kristen Johnson
@es
Kristen Johnson
@nl
Kristen Johnson
@sl
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0000-0003-0788-7217