Elevated expression of LSD1 (Lysine-specific demethylase 1) during tumour progression from pre-invasive to invasive ductal carcinoma of the breast - Wikidata - wikimedia - TriplyDB

Elevated expression of LSD1 (Lysine-specific demethylase 1) during tumour progression from pre-invasive to invasive ductal carcinoma of the breast

Elevated expression of LSD1 (Lysine-specific demethylase 1) during tumour progression from pre-invasive to invasive ductal carcinoma of the breast

http://www.wikidata.org/entity/Q34392800

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Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting Predictors and Modulators of Synthetic Lethality: An Update on PARP Inhibitors and Personalized Medicine KDM1 class flavin-dependent protein lysine demethylases High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients.Lysine-specific demethylase 1 in breast cancer cells contributes to the production of endogenous formaldehyde in the metastatic bone cancer pain model of rats.CoREST1 promotes tumor formation and tumor stroma interactions in a mouse model of breast cancer.Expression of Lysine-specific demethylase 1 in human epithelial ovarian cancer.Epigenetic regulation of LSD1 during mammary carcinogenesis.The malignant brain tumor (MBT) domain protein SFMBT1 is an integral histone reader subunit of the LSD1 demethylase complex for chromatin association and epithelial-to-mesenchymal transition.LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMP LSD1 binds to HPV16 E7 and promotes the epithelial-mesenchymal transition in cervical cancer by demethylating histones at the Vimentin promoter.Targeted therapy of epigenomic regulatory mechanisms controlling the epithelial to mesenchymal transition during tumor progression.Epigenetic reprogramming in breast cancer: from new targets to new therapies.Inhibitors of Protein Methyltransferases and Demethylases.Marked for death: targeting epigenetic changes in cancer.Functional interaction of histone deacetylase 5 (HDAC5) and lysine-specific demethylase 1 (LSD1) promotes breast cancer progression.TCPs: privileged scaffolds for identifying potent LSD1 inhibitors for cancer therapy.ERRα induces H3K9 demethylation by LSD1 to promote cell invasion.The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastoma.Phosphorylation of LSD1 at Ser112 is crucial for its function in induction of EMT and metastasis in breast cancer.LSD1 demethylates HIF1α to inhibit hydroxylation and ubiquitin-mediated degradation in tumor angiogenesis.ASXL2 promotes proliferation of breast cancer cells by linking ERα to histone methylation.Analysis of the levels of lysine-specific demethylase 1 (LSD1) mRNA in human ovarian tumors and the effects of chemical LSD1 inhibitors in ovarian cancer cell lines.ERRα protein is stabilized by LSD1 in a demethylation-independent manner.LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer.New histone demethylase LSD1 inhibitor selectively targets teratocarcinoma and embryonic carcinoma cells.Transcriptional deregulation underlying the pathogenesis of small cell lung cancer.Optimizing poly (ADP-ribose) polymerase inhibition through combined epigenetic and immunotherapy

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Elevated expression of LSD1 (Lysine-specific demethylase 1) during tumour progression from pre-invasive to invasive ductal carcinoma of the breast

http://www.wikidata.org/entity/Q34392800

description

2012 nî lūn-bûn

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2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2012 թվականի օգոստոսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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Elevated expression of LSD1 (L ...... ductal carcinoma of the breast

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Elevated expression of LSD1 (L ...... ductal carcinoma of the breast

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Elevated expression of LSD1 (L ...... ductal carcinoma of the breast

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Elevated expression of LSD1 (L ...... ductal carcinoma of the breast

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Elevated expression of LSD1

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BMC Clinical Pathology

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Annette Gnatzy

http://www.w3.org/2001/XMLSchema#string

Henning Lorenzen

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Jutta Kirfel

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Nuran Serce

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Reinhard Buettner

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Susanne Steiner

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P2860

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

The language of covalent histone modifications

Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

Regulation of LSD1 histone demethylase activity by its associated factors

Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence

Carcinogen-induced histone alteration in normal human mammary epithelial cells.

Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications.

Biologic and immunologic effects of preoperative trastuzumab for ductal carcinoma in situ of the breast

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