Using Markov state models to develop a mechanistic understanding of protein kinase A regulatory subunit RIα activation in response to cAMP binding

Using Markov state models to develop a mechanistic understanding of protein kinase A regulatory subunit RIα activation in response to cAMP binding

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http://www.wikidata.org/entity/Q34396964
Bridging scales through multiscale modeling: a case study on protein kinase AMapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα.Allostery through the computational microscope: cAMP activation of a canonical signalling domainTransition path theory analysis of c-Src kinase activationDiscovery of Allostery in PKA Signaling.Molecular Simulations Reveal an Unresolved Conformation of the Type IA Protein Kinase A Regulatory Subunit and Suggest Its Role in the cAMP Regulatory Mechanism.Structure of a PKA RIα Recurrent Acrodysostosis Mutant Explains Defective cAMP-Dependent Activation.Switching Cyclic Nucleotide-Selective Activation of Cyclic Adenosine Monophosphate-Dependent Protein Kinase Holoenzyme Reveals Distinct Roles of Tandem Cyclic Nucleotide-Binding Domains.Phosphorylation of Protein Kinase A (PKA) regulatory subunit RIα by Protein Kinase G (PKG) primes PKA for catalytic activity in cells.cAMP-Dependent Protein Kinase and cGMP-Dependent Protein Kinase as Cyclic Nucleotide Effectors.PKA-RII subunit phosphorylation precedes activation by cAMP and regulates activity termination.Switching of the folding-energy landscape governs the allosteric activation of protein kinase A
P2860

Using Markov state models to develop a mechanistic understanding of protein kinase A regulatory subunit RIα activation in response to cAMP binding

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http://www.wikidata.org/entity/Q34396964
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2014 nî lūn-bûn
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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
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2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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Using Markov state models to d ...... on in response to cAMP binding
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Using Markov state models to d ...... on in response to cAMP binding
@en
Using Markov state models to d ...... on in response to cAMP binding
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type
label
Using Markov state models to d ...... on in response to cAMP binding
@ast
Using Markov state models to d ...... on in response to cAMP binding
@en
Using Markov state models to d ...... on in response to cAMP binding
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prefLabel
Using Markov state models to d ...... on in response to cAMP binding
@ast
Using Markov state models to d ...... on in response to cAMP binding
@en
Using Markov state models to d ...... on in response to cAMP binding
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Using Markov state models to d ...... on in response to cAMP binding
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932