Human endogenous retrovirus rec interferes with germ cell development in mice and may cause carcinoma in situ, the predecessor lesion of germ cell tumors.
about
'There and back again': revisiting the pathophysiological roles of human endogenous retroviruses in the post-genomic eraEndogenous retroviruses and the development of cancerHuman endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice?Are human endogenous retroviruses pathogenic? An approach to testing the hypothesisDeletion of the pluripotency-associated Tex19.1 gene causes activation of endogenous retroviruses and defective spermatogenesis in miceAn Ecological Framework of the Human Virome Provides Classification of Current Knowledge and Identifies Areas of Forthcoming DiscoveryIdentification of diverse full-length endogenous betaretroviruses in megabats and microbatsHuman endogenous retrovirus HERV-K(HML-2) encodes a stable signal peptide with biological properties distinct from RecAt least 50% of human-specific HERV-K (HML-2) long terminal repeats serve in vivo as active promoters for host nonrepetitive DNA transcriptionExpression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.Regulation of the human endogenous retrovirus K (HML-2) transcriptome by the HIV-1 Tat protein.HIV-1 infection leads to increased transcription of human endogenous retrovirus HERV-K (HML-2) proviruses in vivo but not to increased virion production.Biochemical analysis of the complex between the tetrameric export adapter protein Rec of HERV-K/HML-2 and the responsive RNA element RcRE pck30.HERV-K(HML-2), a seemingly silent subtenant - but still waters run deep.Involvement of endogenous retroviruses in prion diseases.Expression profiles of endogenous retroviruses in Old World monkeysExpression-analysis of the human endogenous retrovirus HERV-K in human astrocytic tumors.HERV-K(HML-2) rec and np9 transcripts not restricted to disease but present in many normal human tissues.Expression pattern analysis of transcribed HERV sequences is complicated by ex vivo recombination.Vaccination with cancer- and HIV infection-associated endogenous retrotransposable elements is safe and immunogenicExpression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1.Human RNA "rumor" viruses: the search for novel human retroviruses in chronic diseaseHuman endogenous retrovirus K (HML-2) elements in the plasma of people with lymphoma and breast cancer.HERV-K(HML-2), the Best Preserved Family of HERVs: Endogenization, Expression, and Implications in Health and Disease.Human Endogenous Retroviruses-K (HML-2) Expression Is Correlated with Prognosis and Progress of Hepatocellular Carcinoma.Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germlineEndogenous retroviruses and human disease.Association of endogenous retroviruses and long terminal repeats with human disorders.Modulation of human endogenous retrovirus (HERV) transcription during persistent and de novo HIV-1 infection.The impact of transposable elements on mammalian development.Staufen-1 interacts with the human endogenous retrovirus family HERV-K(HML-2) rec and gag proteins and increases virion production.Transcriptional profiling of human endogenous retrovirus group HERV-K(HML-2) loci in melanomaThe Rec protein of HERV-K(HML-2) upregulates androgen receptor activity by binding to the human small glutamine-rich tetratricopeptide repeat protein (hSGT).The NP9 protein encoded by the human endogenous retrovirus HERV-K(HML-2) negatively regulates gene activation of the Epstein-Barr virus nuclear antigen 2 (EBNA2).Expression of human endogenous retrovirus K is stimulated by ultraviolet radiation in melanoma.Human endogenous retrovirus family HERV-K(HML-2) RNA transcripts are selectively packaged into retroviral particles produced by the human germ cell tumor line Tera-1 and originate mainly from a provirus on chromosome 22q11.21Making a virtue of necessity: the pleiotropic role of human endogenous retroviruses in cancer.Physical and functional interactions of human endogenous retrovirus proteins Np9 and rec with the promyelocytic leukemia zinc finger protein.Overexpression of TET dioxygenases in seminomas associates with low levels of DNA methylation and hydroxymethylation.Susceptibility of Human Endogenous Retrovirus Type-K to Reverse Transcriptase Inhibitors.
P2860
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P2860
Human endogenous retrovirus rec interferes with germ cell development in mice and may cause carcinoma in situ, the predecessor lesion of germ cell tumors.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Human endogenous retrovirus re ...... or lesion of germ cell tumors.
@ast
Human endogenous retrovirus re ...... or lesion of germ cell tumors.
@en
Human endogenous retrovirus re ...... or lesion of germ cell tumors.
@nl
type
label
Human endogenous retrovirus re ...... or lesion of germ cell tumors.
@ast
Human endogenous retrovirus re ...... or lesion of germ cell tumors.
@en
Human endogenous retrovirus re ...... or lesion of germ cell tumors.
@nl
prefLabel
Human endogenous retrovirus re ...... or lesion of germ cell tumors.
@ast
Human endogenous retrovirus re ...... or lesion of germ cell tumors.
@en
Human endogenous retrovirus re ...... or lesion of germ cell tumors.
@nl
P2093
P2860
P356
P1433
P1476
Human endogenous retrovirus re ...... or lesion of germ cell tumors.
@en
P2093
Bernd Lecher
Hermann Herbst
Klaus Roemer
Marlies Sauter
Nikolaus Mueller-Lantzsch
Simone Maurer
Uwe M Galli
P2860
P2888
P304
P356
10.1038/SJ.ONC.1208543
P407
P577
2005-04-01T00:00:00Z
P5875
P6179
1013530412