ERK1/2-dependent vascular endothelial growth factor signaling sustains cyst growth in polycystin-2 defective mice. - Wikidata - wikimedia - TriplyDB

ERK1/2-dependent vascular endothelial growth factor signaling sustains cyst growth in polycystin-2 defective mice.

ERK1/2-dependent vascular endothelial growth factor signaling sustains cyst growth in polycystin-2 defective mice.

http://www.wikidata.org/entity/Q34399971

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Polycystic liver diseases: advanced insights into the molecular mechanisms Experimental therapies and ongoing clinical trials to slow down progression of ADPKD The role of hypoxia-inducible factor-1α in zinc oxide nanoparticle-induced nephrotoxicity in vitro and in vivo A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation A mathematical model for mechanotransduction at the early steps of suture formation PPAR-gamma agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease Protein kinase A-dependent pSer(675) -β-catenin, a novel signaling defect in a mouse model of congenital hepatic fibrosis Polycystic liver diseases.Mammalian target of rapamycin regulates vascular endothelial growth factor-dependent liver cyst growth in polycystin-2-defective mice.Aquaporin-1 promotes angiogenesis, fibrosis, and portal hypertension through mechanisms dependent on osmotically sensitive microRNAs Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice.Hypoxia-inducible factor-1α (HIF-1α) and autophagy in polycystic kidney disease (PKD).Screening analysis of candidate gene mutations in a kindred with polycystic liver disease.Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in mice Vascular factors, angiogenesis and biliary tract disease Epithelial-mesenchymal interactions in biliary diseases Polycystic liver diseases: congenital disorders of cholangiocyte signaling Development of the bile ducts: essentials for the clinical hepatologist.Vascular biology of the biliary epithelium Strategies targeting cAMP signaling in the treatment of polycystic kidney disease.Novel therapeutic approaches to autosomal dominant polycystic kidney disease.Therapeutic Targets in Polycystic Liver Disease.An overview of experimental and early investigational therapies for the treatment of polycystic kidney disease.Recent Trends in ADPKD Research.Platelet-derived growth factor-D and Rho GTPases regulate recruitment of cancer-associated fibroblasts in cholangiocarcinoma.Animal models of biliary injury and altered bile acid metabolism.Biliary infection may exacerbate biliary cystogenesis through the induction of VEGF in cholangiocytes of the polycystic kidney (PCK) rat Altered store operated calcium entry increases cyclic 3',5'-adenosine monophosphate production and extracellular signal-regulated kinases 1 and 2 phosphorylation in polycystin-2-defective cholangiocytes.Posttranslational regulation of polycystin-2 protein expression as a novel mechanism of cholangiocyte reaction and repair from biliary damage.Vascular endothelial growth factors in progenitor cells mediated liver repair.Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib.The role of endothelial nitric oxide in the anti-restenotic effects of liraglutide in a mouse model of restenosis.Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response.Profiling of miRNAs and target genes related to cystogenesis in ADPKD mouse models.Multiple postnatal craniofacial anomalies are characterized by conditional loss of polycystic kidney disease 2 (Pkd2).β-catenin and IL-1β dependent CXCL10 production drives progression of disease in a mouse model of Congenital Hepatic Fibrosis.Possible Role of Raf-1 Kinase in the Development of Cerebral Vasospasm and Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats.The combination of an HDAC6 inhibitor and a somatostatin receptor agonist synergistically reduces hepato-renal cystogenesis in an animal model of polycystic liver disease.Graphene Oxide-Copper Nanocomposite-Coated Porous CaP Scaffold for Vascularized Bone Regeneration via Activation of Hif-1α.Primary cilia disruption differentially affects the infiltrating and resident macrophage compartment in the liver.

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ERK1/2-dependent vascular endothelial growth factor signaling sustains cyst growth in polycystin-2 defective mice.

http://www.wikidata.org/entity/Q34399971

description

2009 nî lūn-bûn

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2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

ERK1/2-dependent vascular endo ...... n polycystin-2 defective mice.

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ERK1/2-dependent vascular endo ...... n polycystin-2 defective mice.

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ERK1/2-dependent vascular endo ...... n polycystin-2 defective mice.

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ERK1/2-dependent vascular endo ...... n polycystin-2 defective mice.

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ERK1/2-dependent vascular endo ...... n polycystin-2 defective mice.

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ERK1/2-dependent vascular endo ...... n polycystin-2 defective mice.

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ERK1/2-dependent vascular endo ...... n polycystin-2 defective mice.

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ERK1/2-dependent vascular endo ...... n polycystin-2 defective mice.

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ERK1/2-dependent vascular endo ...... n polycystin-2 defective mice.

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J.GASTRO.2009.09.005

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Gastroenterology

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ERK1/2-dependent vascular endo ...... n polycystin-2 defective mice.

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Carlo Spirli

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Luca Fabris

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Mario Strazzabosco

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Massimiliano Cadamuro

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Romina Fiorotto

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Silvia Lecchi

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Stefan Somlo

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Stefano Okolicsanyi

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Xin Tian

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P2860

Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling

Polycystic disease of the liver

VEGF receptor inhibition blocks liver cyst growth in pkd2(WS25/-) mice

Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2

The ion channel polycystin-2 is required for left-right axis determination in mice

Vascular endothelial growth factor stimulates rat cholangiocyte proliferation via an autocrine mechanism

Effects of angiogenic factor overexpression by human and rodent cholangiocytes in polycystic liver diseases

Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling

Regulation of angiogenesis by hypoxia: role of the HIF system

Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.

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360-371.e7

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10.1053/J.GASTRO.2009.09.005

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