Finding a better drug for epilepsy: preclinical screening strategies and experimental trial design. - Wikidata - wikimedia - TriplyDB

Finding a better drug for epilepsy: preclinical screening strategies and experimental trial design.

Finding a better drug for epilepsy: preclinical screening strategies and experimental trial design.

http://www.wikidata.org/entity/Q34400159

about

Clonazepam add-on therapy for refractory epilepsy in adults and children Pharmacological Alternatives for the Treatment of Neurodegenerative Disorders: Wasp and Bee Venoms and Their Components as New Neuroactive Tools MicroRNAs in the pathophysiology and treatment of status epilepticus New vistas on astroglia in convulsive and non-convulsive epilepsy highlight novel astrocytic targets for treatment The microRNA miR-124 suppresses seizure activity and regulates CREB1 activity MicroRNA profiles in hippocampal granule cells and plasma of rats with pilocarpine-induced epilepsy--comparison with human epileptic samples.Nitrobenzylthioinosine mimics adenosine to attenuate the epileptiform discharge of hippocampal neurons from epileptic rats.Electroacupuncture-induced attenuation of experimental epilepsy: a comparative evaluation of acupoints and stimulation parameters.New drug classes for the treatment of partial onset epilepsy: focus on perampanel.Role of hormones and neurosteroids in epileptogenesis.Issues for new antiepilepsy drug development.The challenge and promise of anti-epileptic therapy development in animal models.Past and present definitions of epileptogenesis and its biomarkers.Potent Anti-seizure Effects of Locked Nucleic Acid Antagomirs Targeting miR-134 in Multiple Mouse and Rat Models of Epilepsy.Approaches to refractory epilepsy.Novel approaches to anticonvulsant drug discovery.Novel astrocyte targets: new avenues for the therapeutic treatment of epilepsy Epileptogenesis.Astrocytes: a central element in neurological diseases.Proteomic Analysis After Status Epilepticus Identifies UCHL1 as Protective Against Hippocampal Injury.Advancing pharmacologic treatment options for pharmacologic treatment options for children with epilepsy.Novel therapeutic approaches for disease-modification of epileptogenesis for curing epilepsy.Altered sensory processing and dendritic remodeling in hyperexcitable visual cortical networks.Astrocyte uncoupling as a cause of human temporal lobe epilepsy.Epilepsy Treatment: A Futurist View.Meta-Analysis of MicroRNAs Dysregulated in the Hippocampal Dentate Gyrus of Animal Models of Epilepsy.A 2017 review of pharmacotherapy for treating focal epilepsy: where are we now and how will treatment develop?Time evolution of interhemispheric coupling in a model of focal neocortical epilepsy in mice.

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P2860

Finding a better drug for epilepsy: preclinical screening strategies and experimental trial design.

http://www.wikidata.org/entity/Q34400159

description

2012 nî lūn-bûn

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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2012 թվականի հունիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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Finding a better drug for epil ...... and experimental trial design.

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Finding a better drug for epil ...... and experimental trial design.

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Finding a better drug for epil ...... and experimental trial design.

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Finding a better drug for epil ...... and experimental trial design.

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J.1528-1167.2012.03541.X

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Finding a better drug for epil ...... and experimental trial design

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Andrew J Cole

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F Edward Dudek

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Helen Scharfman

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Henrik Klitgaard

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Jeffrey A Loeb

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Jerome Engel

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Kevin J Staley

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Rafal M Kaminski

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Wolfgang Löscher

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P2860

Identification of new epilepsy treatments: issues in preclinical methodology

Modern antiepileptic drug development has failed to deliver: ways out of the current dilemma.

Early identification of refractory epilepsy

Biomarkers and surrogate endpoints: preferred definitions and conceptual framework

Development of spontaneous recurrent seizures after kainate-induced status epilepticus.

Interictal spikes precede ictal discharges in an organotypic hippocampal slice culture model of epileptogenesis.

Continuous electroencephalographic monitoring with radio-telemetry in a rat model of perinatal hypoxia-ischemia reveals progressive post-stroke epilepsy

The effect of the cannabinoid-receptor antagonist, SR141716, on the early stage of kainate-induced epileptogenesis in the adult rat.

Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs.

Prevention or modification of epileptogenesis after brain insults: experimental approaches and translational research.

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Michele Simonato

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