Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase - Wikidata - wikimedia - TriplyDB

Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase

Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase

http://www.wikidata.org/entity/Q34407252

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Raf family kinases: old dogs have learned new tricks Interlinked dual-time feedback loops can enhance robustness to stochasticity and persistence of memory Raf-interactome in tuning the complexity and diversity of Raf function.Negative feedback regulation of the ERK1/2 MAPK pathway Modeling of tumor progression in NSCLC and intrinsic resistance to TKI in loss of PTEN expression Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals.Topological analysis of MAPK cascade for kinetic ErbB signaling.Cellular Ser/Thr-kinase assays using generic peptide substrates.Genome scale modeling in systems biology: algorithms and resources.Targeting signal transduction pathways to eliminate chemotherapeutic drug resistance and cancer stem cells.Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.Human native lipoprotein-induced de novo DNA methylation is associated with repression of inflammatory genes in THP-1 macrophages Brucine suppresses colon cancer cells growth via mediating KDR signalling pathway.Oscillations in MAPK cascade triggered by two distinct designs of coupled positive and negative feedback loops.A single mechanism can explain network-wide insulin resistance in adipocytes from obese patients with type 2 diabetes.The Src-family kinase inhibitor PP2 rescues inducible differentiation events in emergent retinoic acid-resistant myeloblastic leukemia cells.Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging.Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function Raf kinases: function, regulation and role in human cancer.The SH3 domain of Lck modulates T-cell receptor-dependent activation of extracellular signal-regulated kinase through activation of Raf-1.Activation of a cyclic amp-guanine exchange factor in hepatocytes decreases nitric oxide synthase expression.Constitutive activation of Raf-1 induces glioma formation in mice.System properties of ErbB receptor signaling for the understanding of cancer progression.MEK-1 activates C-Raf through a Ras-independent mechanism.BRAFV600E mutation is associated with preferential sensitivity to mitogen-activated protein kinase kinase inhibition in thyroid cancer cell lines.Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.Radiation-induced HIF-1alpha cell survival pathway is inhibited by soy isoflavones in prostate cancer cells.Small G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)·extracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1.Emerging Raf inhibitors.Mechanistic principles of RAF kinase signaling.Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.Tumor adaptation and resistance to RAF inhibitors."RAF" neighborhood: protein-protein interaction in the Raf/Mek/Erk pathway.Optogenetic Control of Ras/Erk Signaling Using the Phy-PIF System.Receptor Level Mechanisms Are Required for Epidermal Growth Factor (EGF)-stimulated Extracellular Signal-regulated Kinase (ERK) Activity Pulses Integrated modulation of phorbol ester-induced Raf activation in EL4 lymphoma cells.GW5074 and PP2 kinase inhibitors implicate nontraditional c-Raf and Lyn function as drivers of retinoic acid-induced maturation.Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors.Diacylglycerol kinase eta augments C-Raf activity and B-Raf/C-Raf heterodimerization.Positive regulation of A-RAF by phosphorylation of isoform-specific hinge segment and identification of novel phosphorylation sites.

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P2860

Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase

http://www.wikidata.org/entity/Q34407252

description

2006 nî lūn-bûn

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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2006 թվականի հունվարին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Identification of novel in viv ...... llular signal-regulated kinase

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Identification of novel in viv ...... llular signal-regulated kinase

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Identification of novel in viv ...... llular signal-regulated kinase

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type

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Identification of novel in viv ...... llular signal-regulated kinase

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Identification of novel in viv ...... llular signal-regulated kinase

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Identification of novel in viv ...... llular signal-regulated kinase

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prefLabel

Identification of novel in viv ...... llular signal-regulated kinase

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Identification of novel in viv ...... llular signal-regulated kinase

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Identification of novel in viv ...... llular signal-regulated kinase

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MBC.E04-12-1123

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Molecular Biology of the Cell

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Identification of novel in viv ...... llular signal-regulated kinase

@en

P2093

Alexander Kaplun

http://www.w3.org/2001/XMLSchema#string

Deborah T Leicht

http://www.w3.org/2001/XMLSchema#string

Guri Tzivion

http://www.w3.org/2001/XMLSchema#string

Hong Ruan

http://www.w3.org/2001/XMLSchema#string

Jun Qin

http://www.w3.org/2001/XMLSchema#string

Jun Zhu

http://www.w3.org/2001/XMLSchema#string

Karina Balan

http://www.w3.org/2001/XMLSchema#string

Michael J Comb

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Vinita Singh-Gupta

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Vitaly Balan

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P2860

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus

Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

Mutations of the BRAF gene in human cancer

Phosphorylation and regulation of Raf by Akt (protein kinase B)

Mechanisms of regulating the Raf kinase family

Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade

Mammalian MAP kinase signalling cascades

Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions

P304

1141-1153

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scholarly article

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10.1091/MBC.E04-12-1123

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3

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17

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2006-01-11T00:00:00Z

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16407412

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phosphorylation

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1382304

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