Effect of bitopertin, a glycine reuptake inhibitor, on negative symptoms of schizophrenia: a randomized, double-blind, proof-of-concept study.
about
Addressing the unmet needs of patients with persistent negative symptoms of schizophrenia: emerging pharmacological treatment optionsTreating Negative Symptoms in Schizophrenia: an UpdateNMDA receptor modulators: an updated patent review (2013-2014)The impact of NMDA receptor hypofunction on GABAergic neurons in the pathophysiology of schizophreniaNeurometabolic abnormalities in schizophrenia and depression observed with magnetic resonance spectroscopy at 7 T.Further characterization of the GlyT-1 inhibitor Org25935: anti-alcohol, neurobehavioral, and gene expression effects.A Novel Bio-Psychosocial-Behavioral Treatment Model in Schizophrenia.Glutamatergic deficit and schizophrenia-like negative symptoms: new evidence from ketamine-induced mismatch negativity alterations in healthy male humans.Relationship between glycine transporter 1 inhibition as measured with positron emission tomography and changes in cognitive performances in nonhuman primatesSchizophrenia drug discovery and development in an evolving era: are new drug targets fulfilling expectations?Hypomania after augmenting venlafaxine and olanzapine with sarcosine in a patient with schizophrenia: a case study.A randomized pilot study of MOtiVation and Enhancement (MOVE) Training for negative symptoms in schizophrenia.Targeting the schizophrenia genome: a fast track strategy from GWAS to clinic.A double-blind randomized study assessing safety and efficacy following one-year adjunctive treatment with bitopertin, a glycine reuptake inhibitor, in Japanese patients with schizophrenia.Modulating NMDA Receptor Function with D-Amino Acid Oxidase Inhibitors: Understanding Functional Activity in PCP-Treated Mouse Model.Glutamate and dopamine in schizophrenia: an update for the 21st centuryCombining 'Bottom-Up' and 'Top-Down' Methods to Assess Ethnic Difference in Clearance: Bitopertin as an Example.Efficacy and Safety of Bitopertin in Patients with Schizophrenia and Predominant Negative Symptoms: Subgroup Analysis of Japanese Patients from the Global Randomized Phase 2 Trial.Targeting of NMDA receptors in new treatments for schizophrenia.Emerging drugs for schizophrenia: an update.Genomics and epigenomics in novel schizophrenia drug discovery: translating animal models to clinical research and back.Thinking and acting beyond the positive: the role of the cognitive and negative symptoms in schizophrenia.Investigational drugs for anxiety in patients with schizophrenia.Drug repurposing and emerging adjunctive treatments for schizophrenia.Pharmacological treatment of negative symptoms in schizophrenia.Glutamatergic agents for schizophrenia: current evidence and perspectives.The impact of genetics on future drug discovery in schizophrenia.Placebo Response and Practice Effects in Schizophrenia Cognition Trials.D-cycloserine in Schizophrenia: New Strategies for Improving Clinical Outcomes by Enhancing Plasticity.Experimental Medicine in Psychiatry New Approaches in Schizophrenia, Depression and Cognition.New drug developments in psychosis: Challenges, opportunities and strategies.Insights About Striatal Circuit Function and Schizophrenia From a Mouse Model of Dopamine D2 Receptor Upregulation.Multitarget drug discovery projects in CNS diseases: quantitative systems pharmacology as a possible path forward.Conceptualization and treatment of negative symptoms in schizophrenia.Managing Negative Symptoms of Schizophrenia: How Far Have We Come?Mental disorders of known aetiology and precision medicine in psychiatry: a promising but neglected alliance.Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells.New Targets for Schizophrenia Treatment beyond the Dopamine HypothesisPreclinical Reproductive and Developmental Toxicity Profile of a Glycine Transporter Type 1 (Glyt1) Inhibitor.The N-Methyl-D-Aspartate Receptor: Memory, Madness, and More.
P2860
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P2860
Effect of bitopertin, a glycine reuptake inhibitor, on negative symptoms of schizophrenia: a randomized, double-blind, proof-of-concept study.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Effect of bitopertin, a glycin ...... blind, proof-of-concept study.
@ast
Effect of bitopertin, a glycin ...... blind, proof-of-concept study.
@en
Effect of bitopertin, a glycin ...... blind, proof-of-concept study.
@nl
type
label
Effect of bitopertin, a glycin ...... blind, proof-of-concept study.
@ast
Effect of bitopertin, a glycin ...... blind, proof-of-concept study.
@en
Effect of bitopertin, a glycin ...... blind, proof-of-concept study.
@nl
prefLabel
Effect of bitopertin, a glycin ...... blind, proof-of-concept study.
@ast
Effect of bitopertin, a glycin ...... blind, proof-of-concept study.
@en
Effect of bitopertin, a glycin ...... blind, proof-of-concept study.
@nl
P2093
P1433
P1476
Effect of bitopertin, a glycin ...... blind, proof-of-concept study.
@en
P2093
Alexander Bausch
Daniel Umbricht
Daniela Alberati
Edilio Borroni
Eriene A Youssef
Ernest Dorflinger
Frédéric Knoflach
George Garibaldi
Joseph G Wettstein
Luca Santarelli
P304
P356
10.1001/JAMAPSYCHIATRY.2014.163
P407
P577
2014-06-01T00:00:00Z