about
Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosisThe interplay between inflammation and metabolism in rheumatoid arthritisNoncanocial cell death program independent of caspase activation cascade and necroptotic modules is elicited by loss of TGFβ-activated kinase 1.A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis.MicroRNA-146a promotes gastric cancer cell apoptosis by targeting transforming growth factor β-activated kinase 1Reactive oxygen species induce Cox-2 expression via TAK1 activation in synovial fibroblast cells.MUC1-C activates the TAK1 inflammatory pathway in colon cancerInhibition of BMP and of TGFβ receptors downregulates expression of XIAP and TAK1 leading to lung cancer cell death.TAK1 inhibition-induced RIP1-dependent apoptosis in murine macrophages relies on constitutive TNF-α signaling and ROS production.TAK1-regulated expression of BIRC3 predicts resistance to preoperative chemoradiotherapy in oesophageal adenocarcinoma patients.Survival and maintenance of regulatory T cells require the kinase TAK1.TAK1 modulates satellite stem cell homeostasis and skeletal muscle repairEpigenetic regulation of the expression of Il12 and Il23 and autoimmune inflammation by the deubiquitinase Trabid.TAK1 regulates Paneth cell integrity partly through blocking necroptosis.TAK1 determines susceptibility to endoplasmic reticulum stress and leptin resistance in the hypothalamus.Targeting Transforming Growth Factor-Beta1 (TGF-β1) Inhibits Tumorigenesis of Anaplastic Thyroid Carcinoma Cells Through ERK1/2-NFκkB-PUMA Signaling.TAK1 regulates hepatic lipid homeostasis through SREBPEnhancement of hyperthermia-induced apoptosis by 5Z-7-oxozeaenol, a TAK1 inhibitor, in A549 cellsTAK1 inhibitor NG25 enhances doxorubicin-mediated apoptosis in breast cancer cellsInhibition of transforming growth factor β-activated kinase 1 prevents inflammation-related cartilage degradation in osteoarthritisNecroptosis in spontaneously-mutated hematopoietic cells induces autoimmune bone marrow failure in miceTAK1 regulates resident macrophages by protecting lysosomal integrity.Novel Molecular Targets for Chemoprevention in Malignancies of the Head and Neck.N6-Isopentenyladenosine promoted HeLa cell apoptosis through inhibitions of AKT and transforming growth factor β-activated kinase 1 activation.MiR-143 Targeting TAK1 Attenuates Pancreatic Ductal Adenocarcinoma Progression via MAPK and NF-κB Pathway In Vitro.Enhancement of hyperthermia-induced apoptosis by 5Z-7-oxozeaenol, a TAK1 inhibitor, in Molt-4 cells.TAK1 Regulates the Nrf2 Antioxidant System Through Modulating p62/SQSTM1.Developmental checkpoints guarded by regulated necrosis.Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo.Live imaging of transforming growth factor-β activated kinase 1 activation in Lewis lung carcinoma 3LL cells implanted into syngeneic mice and treated with polyinosinic:polycytidylic acid.ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC.SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.NG25, an inhibitor of transforming growth factor‑β‑activated kinase 1, ameliorates neuronal apoptosis in neonatal hypoxic‑ischemic rats.Compound mutations in Bmpr1a and Tak1 synergize facial deformities via increased cell death.The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.Distinct roles of TRAF6 and TAK1 in the regulation of adipocyte survival, thermogenesis program, and high-fat diet-induced obesity.TAK1 regulates skeletal muscle mass and mitochondrial function.TAK1 mediates excessive autophagy via p38 and ERK in cisplatin-induced acute kidney injury.TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth.
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
TAK1 control of cell death.
@ast
TAK1 control of cell death.
@en
TAK1 control of cell death.
@nl
type
label
TAK1 control of cell death.
@ast
TAK1 control of cell death.
@en
TAK1 control of cell death.
@nl
prefLabel
TAK1 control of cell death.
@ast
TAK1 control of cell death.
@en
TAK1 control of cell death.
@nl
P2860
P356
P1476
TAK1 control of cell death.
@en
P2093
J Ninomiya-Tsuji
S R Mihaly
P2860
P2888
P304
P356
10.1038/CDD.2014.123
P50
P577
2014-08-22T00:00:00Z