NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts. - Wikidata - wikimedia - TriplyDB

NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts.

NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts.

http://www.wikidata.org/entity/Q34415231

about

Redox mechanisms in age-related lung fibrosis Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases Role of redoximiRs in fibrogenesis Reciprocal regulation of TGF-β and reactive oxygen species: A perverse cycle for fibrosis Therapeutic targeting of redox signaling in myofibroblast differentiation and age-related fibrotic disease Host responses in tissue repair and fibrosis Recent developments in myofibroblast biology: paradigms for connective tissue remodeling Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system Fibroblasts in fibrosis: novel roles and mediators TGF-β signaling in tissue fibrosis: redox controls, target genes and therapeutic opportunities Myofibroblasts NADPH oxidases in lung health and disease Oxidative stress in cancer and fibrosis: Opportunity for therapeutic intervention with antioxidant compounds, enzymes, and nanoparticles Cancer: An Oxidative Crosstalk between Solid Tumor Cells and Cancer Associated Fibroblasts Roflumilast Prevents the Metabolic Effects of Bleomycin-Induced Fibrosis in a Murine Model Nox4 and redox signaling mediate TGF-β-induced endothelial cell apoptosis and phenotypic switch Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling Reactive oxygen species in inflammation and tissue injury Redox-sensitive MAPK and Notch3 regulate fibroblast differentiation and activation: a dual role of ERK1/2 Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells Role of NADPH oxidases in liver fibrosis.Pulmonary endothelial cell NOX Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells.Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo.Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent.Role of reactive oxygen species in transforming growth factor beta1-induced alpha smooth-muscle actin and collagen production in nasal polyp-derived fibroblasts.NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development.NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling The angiotensin-converting enzyme 2/angiotensin (1-7)/Mas axis protects against lung fibroblast migration and lung fibrosis by inhibiting the NOX4-derived ROS-mediated RhoA/Rho kinase pathway.TRPV1 potentiates TGFβ-induction of corneal myofibroblast development through an oxidative stress-mediated p38-SMAD2 signaling loop.Role of hyaluronan and hyaluronan-binding proteins in human asthma.Tacrolimus increases Nox4 expression in human renal fibroblasts and induces fibrosis-related genes by aberrant TGF-beta receptor signalling A key role for NOX4 in epithelial cell death during development of lung fibrosis.Dermal delivery of HSP47 siRNA with NOX4-modulating mesoporous silica-based nanoparticles for treating fibrosis.NOX Modifiers-Just a Step Away from Application in the Therapy of Airway Inflammation?Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance Increased nicotinamide adenine dinucleotide phosphate oxidase 4 expression mediates intrinsic airway smooth muscle hypercontractility in asthma.Nox4 involvement in TGF-beta and SMAD3-driven induction of the epithelial-to-mesenchymal transition and migration of breast epithelial cells.TGF-β1/FGF-2 signaling mediates the 15-HETE-induced differentiation of adventitial fibroblasts into myofibroblasts miR-9-5p suppresses pro-fibrogenic transformation of fibroblasts and prevents organ fibrosis by targeting NOX4 and TGFBR2

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P2860

NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts.

http://www.wikidata.org/entity/Q34415231

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

NOX4/NADPH oxidase expression ...... entiation into myofibroblasts.

@ast

NOX4/NADPH oxidase expression ...... entiation into myofibroblasts.

@en

NOX4/NADPH oxidase expression ...... entiation into myofibroblasts.

@nl

type

label

NOX4/NADPH oxidase expression ...... entiation into myofibroblasts.

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NOX4/NADPH oxidase expression ...... entiation into myofibroblasts.

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NOX4/NADPH oxidase expression ...... entiation into myofibroblasts.

@nl

prefLabel

NOX4/NADPH oxidase expression ...... entiation into myofibroblasts.

@ast

NOX4/NADPH oxidase expression ...... entiation into myofibroblasts.

@en

NOX4/NADPH oxidase expression ...... entiation into myofibroblasts.

@nl

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NOX4/NADPH oxidase expression ...... rentiation into myofibroblasts

@en

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Bruno Crestani

http://www.w3.org/2001/XMLSchema#string

Delphine Goven

http://www.w3.org/2001/XMLSchema#string

Fabienne Prost

http://www.w3.org/2001/XMLSchema#string

Nadia Amara

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Rachel Muloway

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P2860

The myofibroblast: one function, multiple origins

Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase

NOX enzymes and the biology of reactive oxygen

How cells read TGF-beta signals

Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema.

Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation.

NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts.

Reactive oxygen species production via NADPH oxidase mediates TGF-beta-induced cytoskeletal alterations in endothelial cells.

Oxidative stress in pulmonary fibrosis: a possible role for redox modulatory therapy.

Endogenous TGF-beta activation by reactive oxygen species is key to Foxp3 induction in TCR-stimulated and HIV-1-infected human CD4+CD25- T cells.

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733-738

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10.1136/THX.2009.113456

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8

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65

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Jorge Boczkowski

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2010-08-01T00:00:00Z

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45505151

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20685750

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pulmonary fibrosis

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3004009

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