Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.
about
The expression of the ubiquitin ligase subunit Cks1 in human breast cancerAssociation of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progressionA growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.Modulation of p27(Kip1) levels by the cyclin encoded by Kaposi's sarcoma-associated herpesvirusRole of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle.Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancerSmad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoNRole of the F-box protein Skp2 in lymphomagenesisIdentification and characterization of a novel human hepatocellular carcinoma-associated geneDegradation of transcription repressor ZBRK1 through the ubiquitin-proteasome pathway relieves repression of Gadd45a upon DNA damageRole of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradationTransforming growth factor-beta, transforming growth factor-beta receptor II, and p27Kip1 expression in nontumorous and neoplastic human pituitariesRegulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferationRole of the F-box protein Skp2 in adhesion-dependent cell cycle progressionThe cyclin dependent kinase inhibitor p27 and its prognostic role in breast cancer.The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells.p27Kip1 is expressed in proliferating cells in its form phosphorylated on threonine 187Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancerRole of T198 modification in the regulation of p27(Kip1) protein stability and functionDegradation of B-Myb by ubiquitin-mediated proteolysis: involvement of the Cdc34-SCF(p45Skp2) pathwayExpression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational controlPromotion of S-phase entry and cell growth under serum starvation by SAG/ROC2/Rbx2/Hrt2, an E3 ubiquitin ligase component: association with inhibition of p27 accumulationDirect binding of the signal-transducing adaptor Grb2 facilitates down-regulation of the cyclin-dependent kinase inhibitor p27Kip1Pathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2Inactivation of p57KIP2 by regional promoter hypermethylation and histone deacetylation in human tumorsMutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cellsCathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasisp27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cellsFrom bench to bedside: lessons learned in translating preclinical studies in cancer drug developmentUbiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formationThe ubiquitin-proteasome pathway: on protein death and cell lifeAssociations Among -TrCP, an E3 Ubiquitin Ligase Receptor, -Catenin, and NF- B in Colorectal CancerThe yin-yang of DNA damage response: roles in tumorigenesis and cellular senescence.Genetic variants of p21 and p27 and hepatocellular cancer risk in a Chinese Han population: a case-control study.Regulation of the G1 to S transition by the ubiquitin pathway.Bcl-2 protein expression is associated with p27 and p53 protein expressions and MIB-1 counts in breast cancerExpression of ubiquitin carboxy-terminal hydrolase-l1 in photocoagulated human retinal pigment epithelial cells.A mechanism misregulating p27 in tumors discovered in a functional genomic screen.p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers.Prognostic implications of expression of the cell cycle inhibitor protein p27Kip1.
P2860
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P2860
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.
description
1997 nî lūn-bûn
@nan
1997 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Increased proteasome-dependent ...... ressive colorectal carcinomas.
@ast
Increased proteasome-dependent ...... ressive colorectal carcinomas.
@en
Increased proteasome-dependent ...... ressive colorectal carcinomas.
@nl
type
label
Increased proteasome-dependent ...... ressive colorectal carcinomas.
@ast
Increased proteasome-dependent ...... ressive colorectal carcinomas.
@en
Increased proteasome-dependent ...... ressive colorectal carcinomas.
@nl
prefLabel
Increased proteasome-dependent ...... ressive colorectal carcinomas.
@ast
Increased proteasome-dependent ...... ressive colorectal carcinomas.
@en
Increased proteasome-dependent ...... ressive colorectal carcinomas.
@nl
P2093
P356
P1433
P1476
Increased proteasome-dependent ...... gressive colorectal carcinomas
@en
P2093
P2888
P304
P356
10.1038/NM0297-231
P407
P577
1997-02-01T00:00:00Z