Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene
about
RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesisThe gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growthMolecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cellsNuclear import of the ran exchange factor, RCC1, is mediated by at least two distinct mechanismsStructural Basis of Targeting the Exportin CRM1 in CancerChromatin binding of RCC1 during mitosis is important for its nuclear localization in interphaseGSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization.Saccharomyces cerevisiae putative G protein, Gtr1p, which forms complexes with itself and a novel protein designated as Gtr2p, negatively regulates the Ran/Gsp1p G protein cycle through Gtr2pRestoration of lipopolysaccharide-mediated B-cell response after expression of a cDNA encoding a GTP-binding proteinbeta-catenin can be transported into the nucleus in a Ran-unassisted mannerTransport into and out of the nucleus.Disruption of the ran system by cysteine oxidation of the nucleotide exchange factor RCC1Fluorescence resonance energy transfer biosensors that detect Ran conformational changes and a Ran x GDP-importin-beta -RanBP1 complex in vitro and in intact cells.A systems analysis of importin-{alpha}-{beta} mediated nuclear protein importMCAK-independent functions of ch-Tog/XMAP215 in microtubule plus-end dynamics.Nuclear import of the U1A splicesome protein is mediated by importin alpha /beta and Ran in living mammalian cells.Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily.Nucleolar accumulation of poly (A)+ RNA in heat-shocked yeast cells: implication of nucleolar involvement in mRNA transport.RCC1 and nuclear organization.Nuclear transport and cancer: from mechanism to intervention.A mammalian temperature-sensitive mutation affecting G1 progression results from a single amino acid substitution in asparagine synthetase.The maternally expressed Drosophila gene encoding the chromatin-binding protein BJ1 is a homolog of the vertebrate gene Regulator of Chromatin Condensation, RCC1Mutation of the hamster cell cycle gene RCC1 is complemented by the homologous genes of Drosophila and S.cerevisiae.Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progressionNuMA is required for the proper completion of mitosis.Functional analysis of key nuclear trafficking components reveals an atypical Ran network required for parasite pathogenesis.Spatial and temporal coordination of mitosis by Ran GTPase.Premature chromosome condensation in humans associated with microcephaly and mental retardation: a novel autosomal recessive condition.A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation.The site of RanGTP generation can act as an organizational cue for mitotic microtubules.Live imaging system for visualizing nuclear pore complex (NPC) formation during interphase in mammalian cells.Ran GTPase guanine nucleotide exchange factor RCC1 is phosphorylated on serine 11 by cdc2 kinase in vitro.Nd6p, a novel protein with RCC1-like domains involved in exocytosis in Paramecium tetraurelia.beta-subunit of nuclear pore-targeting complex (importin-beta) can be exported from the nucleus in a Ran-independent manner.Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis.Premature chromatin condensation induced by loss of RCC1 is inhibited by GTP- and GTPgammaS-Ran, but not GDP-Ran.SV40 T antigen increases the expression and activities of p34cdc2, cyclin A, and cyclin B prior to immortalization of human diploid fibroblasts.EBNA1: Oncogenic Activity, Immune Evasion and Biochemical Functions Provide Targets for Novel Therapeutic Strategies against Epstein-Barr Virus- Associated Cancers.Ran out of the nucleus for apoptosis.
P2860
Q24318977-3D543C7E-8968-4F15-A96D-9223DE11BA4BQ24319927-023F268B-0DDA-44E3-8FE2-3601007CA8FFQ24613548-1F605B22-25F6-45B1-8C2A-8D074D2E5E0DQ24629674-18551A4D-F016-4B9B-B81E-E9982A9DF15DQ24670107-1112CE10-EBC2-4232-8AC2-B744F566F636Q26781513-210557E4-451C-4FDB-B772-A91DF5874275Q27305266-BA2183C2-1D26-49AB-A981-FE477E5CA1CDQ27936269-56872DCD-8E75-438A-A702-C2B34AB1296AQ27936663-449B79E7-281D-4D45-A9FF-171864780EFEQ28588927-0D009899-C9B2-4AA6-ABBE-400DAD36910FQ28640339-8DD579E8-6222-484A-8113-3C35530E8295Q29615611-D51D944E-8E5C-469A-8590-211E79CF20C2Q30301217-DC7A6FD4-8B9E-42A0-9E6A-F13DFE0E9F3CQ30309399-51076D5A-4DC0-4E97-84F4-907D2548239CQ30436382-55B2F102-BF60-4814-BDA9-49ADFAEE62B1Q30484856-8475A309-D868-4A17-A35D-8F06F7398FE6Q30984798-D98FE839-35AE-4FE2-A46C-F1B6725C6625Q34056045-B31A1958-F5D4-40BB-AB21-2640EC248D20Q34452986-48B6FEA6-6E47-4038-BB66-3206C2B7F88FQ34671494-108977D7-A88E-4FA6-B762-C5AC49A3E25CQ35633427-7C56627A-F5A6-4DD8-8701-42B31F2B1FBDQ35845723-49C86075-BE35-4A43-AFB5-DA735270F944Q35924801-ED2C2336-2772-4792-84E4-30F5219172FEQ35924905-D66E5403-6D10-4F32-8F6A-4A15571F9E31Q36234292-867AA4D4-29E2-4377-8B17-500B268C9C2AQ36383071-0FEFF523-2043-4B61-B855-C3D38F99C3E2Q36958745-200C7711-08B6-44C0-99C3-55FF531ADF46Q37163028-F3FF5924-41B0-4083-9D43-176894965361Q37216189-ADBB0293-7B2F-452F-979F-0F602668F832Q37639314-293292B6-4E83-4DF0-9D7D-3C019B567B57Q39520776-9AC59F78-9B88-48D8-9AEE-C27D343C77CCQ39704368-2F167778-7F4F-4A7B-81BD-383DB951498FQ39969969-CEDE5FFA-9ED2-419A-911A-53E5D36C5DF1Q40719087-D3364BEF-E91E-45C9-B9F3-016B2D75C08BQ40975251-67E6EF05-DB41-46FB-9F4E-74969392D0A1Q41081110-D3F6B0EF-A48B-42F4-9B3C-2D4B4F05ED03Q41190781-3D476C35-E7D0-4391-B8BA-F2986AFACF39Q41233095-3B95D123-C05C-4B11-B56B-9D1164A1300AQ52593708-274E9FB9-86B3-4E93-BD5F-5B06B5AF8E63Q53426185-C1EAE4FA-0D48-4F8B-87D3-729D6DA0B24B
P2860
Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene
description
1990 nî lūn-bûn
@nan
1990 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene
@ast
Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene
@en
Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene
@nl
type
label
Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene
@ast
Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene
@en
Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene
@nl
prefLabel
Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene
@ast
Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene
@en
Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene
@nl
P2093
P2860
P356
P1476
Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene
@en
P2093
K Miyauchi
T Nishimoto
T Sekiguchi
P2860
P304
P356
10.1128/MCB.10.2.577
P407
P577
1990-02-01T00:00:00Z