IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells. - Wikidata - wikimedia - TriplyDB

IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells.

IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells.

http://www.wikidata.org/entity/Q34420821

about

Ectopic lymphoid follicles: inducible centres for generating antigen-specific immune responses within tissues Interleukin-27: balancing protective and pathological immunity Interleukin-27 in T cell immunity Potential of Cells and Cytokines/Chemokines to Regulate Tertiary Lymphoid Structures in Human Diseases Regulators of Tfh Cell Differentiation The regulation of T follicular helper responses during infection Mycobacterium tuberculosis-Specific IL-21+IFN-γ+CD4+ T Cells Are Regulated by IL-12 Gene expression profiling of the response to interferon beta in Epstein-Barr-transformed and primary B cells of patients with multiple sclerosis Ectopic lymphoid neogenesis in rheumatic autoimmune diseases.IL-27 limits central nervous system viral clearance by promoting IL-10 and enhances demyelination.Crucial roles of interleukin-7 in the development of T follicular helper cells and in the induction of humoral immunity.IL-12 family cytokines: immunological playmakers IL-27-induced modulation of autoimmunity and its therapeutic potential.Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3.IL-27 is required for shaping the magnitude, affinity distribution, and memory of T cells responding to subunit immunization.CD4 T Cells Mediate Both Positive and Negative Regulation of the Immune Response to HIV Infection: Complex Role of T Follicular Helper Cells and Regulatory T Cells in Pathogenesis The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa.The Yin and Yang aspects of IL-27 in induction of cancer-specific T-cell responses and immunotherapy.IFN-γ and IL-21 Double Producing T Cells Are Bcl6-Independent and Survive into the Memory Phase in Plasmodium chabaudi Infection.Cell-Intrinsic gp130 Signaling on CD4+ T Cells Shapes Long-Lasting Antiviral Immunity Increased Frequency of T Follicular Helper Cells and Elevated Interleukin-27 Plasma Levels in Patients with Pemphigus.Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages.Functional STAT3 deficiency compromises the generation of human T follicular helper cells.LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6 Distinct germinal center selection at local sites shapes memory B cell response to viral escape The origins, function, and regulation of T follicular helper cells B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1 JAK and STAT signaling molecules in immunoregulation and immune-mediated disease.Cell-intrinsic IL-27 and gp130 cytokine receptor signaling regulates virus-specific CD4⁺ T cell responses and viral control during chronic infection.Preparation, characterization, and determination of immunological activities of transfer factor specific to human sperm antigen.T follicular helper cell diversity and plasticity Blockade of STAT3 in T Cells Inhibits Germinal Center Reactions against Intranasal Allergens.The Emerging Role of Interleukin-21 in Transplantation.The role of IL-27 in the induction of anti-tumor cytotoxic T lymphocyte response The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6 Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets.Modulation of inflammation by interleukin-27.Evaluating the potential of IL-27 as a novel therapeutic agent in HIV-1 infection.Enforced Expression of CXCR5 Drives T Follicular Regulatory-Like Features in Foxp3+ T Cells.Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells

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IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells.

http://www.wikidata.org/entity/Q34420821

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

IL-27 supports germinal center ...... of T follicular helper cells.

@ast

IL-27 supports germinal center ...... of T follicular helper cells.

@en

IL-27 supports germinal center ...... of T follicular helper cells.

@nl

type

label

IL-27 supports germinal center ...... of T follicular helper cells.

@ast

IL-27 supports germinal center ...... of T follicular helper cells.

@en

IL-27 supports germinal center ...... of T follicular helper cells.

@nl

prefLabel

IL-27 supports germinal center ...... of T follicular helper cells.

@ast

IL-27 supports germinal center ...... of T follicular helper cells.

@en

IL-27 supports germinal center ...... of T follicular helper cells.

@nl

P1433

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P2860

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Journal of Experimental Medicine

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IL-27 supports germinal center ...... n of T follicular helper cells

@en

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David A Fulcher

http://www.w3.org/2001/XMLSchema#string

Dimitry M Danilenko

http://www.w3.org/2001/XMLSchema#string

Frederic J de Sauvage

http://www.w3.org/2001/XMLSchema#string

Hart S Dengler

http://www.w3.org/2001/XMLSchema#string

Jennifer H Cox

http://www.w3.org/2001/XMLSchema#string

Marcel Batten

http://www.w3.org/2001/XMLSchema#string

Matthew C Cook

http://www.w3.org/2001/XMLSchema#string

Melanie Wong

http://www.w3.org/2001/XMLSchema#string

Nandhini Ramamoorthi

http://www.w3.org/2001/XMLSchema#string

Noelyn M Kljavin

http://www.w3.org/2001/XMLSchema#string

P2860

WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of iepsilon transcription and immunoglobulin E switching

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

Differential effects of IL-27 on human B cell subsets

Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus

Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

Bcl6 mediates the development of T follicular helper cells

Development of Th1-type immune responses requires the type I cytokine receptor TCCR

P304

2895-2906

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scholarly article

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10.1084/JEM.20100064

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13

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207

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Patrick Caplazi

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2010-11-22T00:00:00Z

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49629263

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21098093

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3005229

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