Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis.
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Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94Differential requirement of GRP94 and GRP78 in mammary gland development.Targeted deletion of ER chaperone GRP94 in the liver results in injury, repopulation of GRP94-positive hepatocytes, and spontaneous hepatocellular carcinoma development in aged miceEndoplasmic reticulum heat shock protein gp96 maintains liver homeostasis and promotes hepatocellular carcinogenesis.Targeting the glucose-regulated protein-78 abrogates Pten-null driven AKT activation and endometrioid tumorigenesis.Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis.Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development.Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potentialEndoplasmic reticulum proteins quality control and the unfolded protein response: the regulative mechanism of organisms against stress injuries.Transgenic mouse models generated by hydrodynamic transfection for genetic studies of liver cancer and preclinical testing of anti-cancer therapy.Targeting the ER-autophagy system in the trabecular meshwork to treat glaucomaExpert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA).Glucose-regulated protein 94 mediates cancer progression via AKT and eNOS in hepatocellular carcinoma.The rise of proteostasis promoters.Differential Impacts of Soybean and Fish Oils on Hepatocyte Lipid Droplet Accumulation and Endoplasmic Reticulum Stress in Primary Rabbit Hepatocytes.Dysregulated expression of proteins associated with ER stress, autophagy and apoptosis in tissues from nonalcoholic fatty liver diseaseEndoplasmic reticulum heat shock protein gp96/grp94 is a pro-oncogenic chaperone, not a tumor suppressor.Reply: To PMID 24027047.New insights into cholangiocarcinoma: multiple stems and related cell lineages of origin.Glucose-regulated protein 94 mediates progression and metastasis of esophageal squamous cell carcinoma via mitochondrial function and the NF-kB/COX-2/VEGF axis.Polyamine signal through gap junctions: A key regulator of proliferation and gap-junction organization in mammalian tissues?Crosstalk of LKB1- and PTEN-regulated signals in liver morphogenesis and tumor development.
P2860
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P2860
Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Liver-specific knockout of GRP ...... celerates liver tumorigenesis.
@ast
Liver-specific knockout of GRP ...... celerates liver tumorigenesis.
@en
Liver-specific knockout of GRP ...... celerates liver tumorigenesis.
@nl
type
label
Liver-specific knockout of GRP ...... celerates liver tumorigenesis.
@ast
Liver-specific knockout of GRP ...... celerates liver tumorigenesis.
@en
Liver-specific knockout of GRP ...... celerates liver tumorigenesis.
@nl
prefLabel
Liver-specific knockout of GRP ...... celerates liver tumorigenesis.
@ast
Liver-specific knockout of GRP ...... celerates liver tumorigenesis.
@en
Liver-specific knockout of GRP ...... celerates liver tumorigenesis.
@nl
P2093
P2860
P356
P1433
P1476
Liver-specific knockout of GRP ...... ccelerates liver tumorigenesis
@en
P2093
Bangyan L Stiles
Biquan Luo
Chun-Chih Tseng
Gary Kanel
Kyle Pfaffenbach
Wan-Ting Chen
P2860
P304
P356
10.1002/HEP.26711
P407
P50
P577
2014-01-27T00:00:00Z