HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death.
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ATP-Competitive MLKL Binders Have No Functional Impact on NecroptosisBio-Zombie: the rise of pseudoenzymes in biology.Evolutionary divergence of the necroptosis effector MLKL.A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer.Thermoregulation as a disease tolerance defense strategy.Insane in the membrane: a structural perspective of MLKL function in necroptosis.The Inflammatory Signal Adaptor RIPK3: Functions Beyond Necroptosis.Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis.Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury.Necroptosis: Mechanisms and Relevance to Disease.Heat shock protein 90 regulates necroptosis by modulating multiple signaling effectors.miRNA-21 ablation protects against liver injury and necroptosis in cholestasis.Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.Inhibition of HSP90α protects cultured neurons from oxygen-glucose deprivation induced necroptosis by decreasing RIP3 expression.Inhibition of calpain on oxygen glucose deprivation-induced RGC-5 necroptosis.Molecular mechanism and therapy application of necrosis during myocardial injury.The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis.Ripk3 promotes ER stress-induced necroptosis in cardiac IR injury: A mechanism involving calcium overload/XO/ROS/mPTP pathway.Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis.Necroptosis: MLKL Polymerization
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P2860
HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
HSP90 activity is required for ...... ion of necroptotic cell death.
@en
type
label
HSP90 activity is required for ...... ion of necroptotic cell death.
@en
prefLabel
HSP90 activity is required for ...... ion of necroptotic cell death.
@en
P2093
P2860
P50
P356
P1476
HSP90 activity is required for ...... tion of necroptotic cell death
@en
P2093
J M Hildebrand
M C Tanzer
P2860
P356
10.1038/CDDIS.2015.386
P577
2016-01-14T00:00:00Z