Allosteric suppression of HIV-1 reverse transcriptase structural dynamics upon inhibitor binding
about
Hydrogen exchange mass spectrometry: are we out of the quicksand?Molecular dynamics study of HIV-1 RT-DNA-nevirapine complexes explains NNRTI inhibition and resistance by connection mutationsInvestigating the mutation resistance of nonnucleoside inhibitors of HIV-RT using multiple microsecond atomistic simulations.Global Conformational Dynamics of HIV-1 Reverse Transcriptase Bound to Non-Nucleoside Inhibitors.Biophysical Insights into the Inhibitory Mechanism of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors.Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy.Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase.Differential isotopic enrichment to facilitate characterization of asymmetric multimeric proteins using hydrogen/deuterium exchange mass spectrometry.On-tissue Direct Monitoring of Global Hydrogen/Deuterium Exchange by MALDI Mass Spectrometry: Tissue Deuterium Exchange Mass Spectrometry (TDXMS).Structural basis of the allosteric inhibitor interaction on the HIV-1 reverse transcriptase RNase H domain.Hydrogen/Deuterium Exchange Kinetics Demonstrate Long Range Allosteric Effects of Thumb Site 2 Inhibitors of Hepatitis C Viral RNA-dependent RNA Polymerase.Protein-mediated antagonism between HIV reverse transcriptase ligands nevirapine and MgATP.Conformational Plasticity of the NNRTI-Binding Pocket in HIV-1 Reverse Transcriptase: A Fluorine Nuclear Magnetic Resonance Study.Na+ coordination at the Na2 site of the Na+/I- symporter.Activation of LINE-1 Retrotransposon Increases the Risk of Epithelial-Mesenchymal Transition and Metastasis in Epithelial Cancer.Efavirenz binding site in HIV-1 reverse transcriptase monomers.The interplay of structure and dynamics: insights from a survey of HIV-1 reverse transcriptase crystal structures.Identification of new potential HIV-1 reverse transcriptase inhibitors by QSAR modeling and structure-based virtual screening.Conformational dynamics of human protein kinase CK2α and its effect on function and inhibition.A computational study for rational HIV-1 non-nucleoside Reverse Transcriptase inhibitor selection and discovery of novel allosteric pockets for inhibitor design.Thermodynamic Profiling of Carbonic Anhydrase Inhibitors
P2860
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P2860
Allosteric suppression of HIV-1 reverse transcriptase structural dynamics upon inhibitor binding
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Allosteric suppression of HIV- ...... ynamics upon inhibitor binding
@ast
Allosteric suppression of HIV- ...... ynamics upon inhibitor binding
@en
Allosteric suppression of HIV- ...... ynamics upon inhibitor binding
@nl
type
label
Allosteric suppression of HIV- ...... ynamics upon inhibitor binding
@ast
Allosteric suppression of HIV- ...... ynamics upon inhibitor binding
@en
Allosteric suppression of HIV- ...... ynamics upon inhibitor binding
@nl
prefLabel
Allosteric suppression of HIV- ...... ynamics upon inhibitor binding
@ast
Allosteric suppression of HIV- ...... ynamics upon inhibitor binding
@en
Allosteric suppression of HIV- ...... ynamics upon inhibitor binding
@nl
P2093
P2860
P1433
P1476
Allosteric suppression of HIV- ...... ynamics upon inhibitor binding
@en
P2093
James M Seckler
Mary D Barkley
Patrick L Wintrode
P2860
P304
P356
10.1016/J.BPJ.2010.11.004
P407
P577
2011-01-01T00:00:00Z