Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development
about
Identification of PITX1 as a TERT suppressor gene located on human chromosome 5Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancerBRAF V600E and TERT promoter mutations cooperatively identify the most aggressive papillary thyroid cancer with highest recurrenceFunctional evaluation of TERT-CLPTM1L genetic variants associated with susceptibility of papillary thyroid carcinomaTERT promoter mutations and their association with BRAF V600E mutation and aggressive clinicopathological characteristics of thyroid cancer.Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging.The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in miceRegulation of the human catalytic subunit of telomerase (hTERT).Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.Alive and well? Exploring disease by studying lifespan.Regulation of senescence in cancer and aging.PinX1 the tail on the chromosomeGenetic analysis of myc and telomerase interactions in vivo.How does genome instability affect lifespan?: roles of rDNA and telomeres.Telomerase abrogation dramatically accelerates TRF2-induced epithelial carcinogenesis.PinX1: a sought-after major tumor suppressor at human chromosome 8p23Dyrk2-associated EDD-DDB1-VprBP E3 ligase inhibits telomerase by TERT degradationExpression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivoHIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complexFrequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease.Telomerase at the intersection of cancer and aging.Association between leukocyte telomere length and glioma risk: a case-control study.Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice.Near-to-perfect homeostasis: examples of universal aging rule which germline evades.The role of telomere shortening in somatic stem cells and tissue aging: lessons from telomerase model systems.DNA Damage, DNA Repair, Aging, and NeurodegenerationTelomerase stimulates ribosomal DNA transcription under hyperproliferative conditions.Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.Moderate stem-cell telomere shortening rate postpones cancer onset in a stochastic model.
P2860
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P2860
Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Cooperation between p53 mutati ...... spontaneous cancer development
@ast
Cooperation between p53 mutati ...... spontaneous cancer development
@en
Cooperation between p53 mutati ...... spontaneous cancer development
@nl
type
label
Cooperation between p53 mutati ...... spontaneous cancer development
@ast
Cooperation between p53 mutati ...... spontaneous cancer development
@en
Cooperation between p53 mutati ...... spontaneous cancer development
@nl
prefLabel
Cooperation between p53 mutati ...... spontaneous cancer development
@ast
Cooperation between p53 mutati ...... spontaneous cancer development
@en
Cooperation between p53 mutati ...... spontaneous cancer development
@nl
P2860
P1476
Cooperation between p53 mutati ...... spontaneous cancer development
@en
P2093
Juana M Flores
P2860
P304
P356
10.1128/MCB.22.20.7291-7301.2002
P407
P577
2002-10-01T00:00:00Z