Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
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Enzyme induction and cytotoxicity in human hepatocytes by chlorpyrifos and N,N-diethyl-m-toluamide (DEET).The molecular biology, biochemistry, and physiology of human steroidogenesis and its disordersIn silico assay development for screening of tetracyclic triterpenoids as anticancer agents against human breast cancer cell line MCF7Summary of information on human CYP enzymes: human P450 metabolism data.17α-alkynyl 3α, 17β-androstanediol non-clinical and clinical pharmacology, pharmacokinetics and metabolism.Decreased hippocampal volume and increased anxiety in a transgenic mouse model expressing the human CYP2C19 gene.Metabolism of 20-hydroxyvitamin D3 by mouse liver microsomesDrug-Drug Interactions, Effectiveness, and Safety of Hormonal Contraceptives in Women Living with HIVNew insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme.Inactive alleles of cytochrome P450 2C19 may be positively selected in human evolutionWhy human cytochrome P450c21 is a progesterone 21-hydroxylase.Immunochemical detection of cytochrome P450 enzymes in liver microsomes of 27 cynomolgus monkeys.Cytochrome P450 enzymes in the brain: emerging evidence of biological significanceElectrocatalysis by subcellular liver fractions bound to carbon nanostructures for stereoselective green drug metabolite synthesis.Nuclear receptors CAR and PXR in the regulation of hepatic metabolism.A Mechanism-Based Model for the Prediction of the Metabolic Sites of Steroids Mediated by Cytochrome P450 3A4.Polymorphisms of Phase I and Phase II Enzymes and Breast Cancer Risk.A human liver microphysiology platform for investigating physiology, drug safety, and disease modelsMetabolism of 17alpha-hydroxyprogesterone caproate by hepatic and placental microsomes of human and baboons.Functional Characterization of Human CYP2C9 Allelic Variants in COS-7 Cells.CYP2C19 2 predicts substantial tamoxifen benefit in postmenopausal breast cancer patients randomized between adjuvant tamoxifen and no systemic treatment.Extraadrenal 21-hydroxylation by CYP2C19 and CYP3A4: effect on 21-hydroxylase deficiency.Cytochromes P450: a structure-based summary of biotransformations using representative substrates.Theoretical characterization of substrate access/exit channels in the human cytochrome P450 3A4 enzyme: involvement of phenylalanine residues in the gating mechanism.Interactions between human cytochrome P450 enzymes and steroids: physiological and pharmacological implications.QSAR of cytochrome inhibitors.A mixture of an environmentally realistic concentration of a phthalate and herbicide reduces testosterone in male fathead minnow (Pimephales promelas) through a novel mechanism of action.What Valproate Does and Doesn't Do.Streptomyces cytochromes P450: applications in drug metabolism.CYP3A4 and VDR gene polymorphisms and the risk of prostate cancer in men with benign prostate hyperplasia.Regioselective hydroxylation of steroid hormones by human cytochromes P450.Monocrotophos Induces the Expression of Xenobiotic Metabolizing Cytochrome P450s (CYP2C8 and CYP3A4) and Neurotoxicity in Human Brain Cells.Emerging roles for brain drug-metabolizing cytochrome P450 enzymes in neuropsychiatric conditions and responses to drugs.In vitro metabolism of testosterone in the horse liver and involvement of equine CYPs 3A89, 3A94 and 3A95.CYP3A4 intron 6 C>T polymorphism (CYP3A4*22) is associated with reduced CYP3A4 protein level and function in human liver microsomesHigh-throughput functional screening of steroid substrates with wild-type and chimeric P450 enzymes.Cytochrome P450 2C19 polymorphisms and valproic acid-induced weight gain.Perfluorononanoic acid in combination with 14 chemicals exerts low-dose mixture effects in rats.Homology modeling and substrate binding study of human CYP2C9 enzyme.Homology modeling and substrate binding study of human CYP2C18 and CYP2C19 enzymes.
P2860
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P2860
Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Progesterone and testosterone ...... 3A4 in human liver microsomes.
@ast
Progesterone and testosterone ...... 3A4 in human liver microsomes.
@en
Progesterone and testosterone ...... 3A4 in human liver microsomes.
@nl
type
label
Progesterone and testosterone ...... 3A4 in human liver microsomes.
@ast
Progesterone and testosterone ...... 3A4 in human liver microsomes.
@en
Progesterone and testosterone ...... 3A4 in human liver microsomes.
@nl
prefLabel
Progesterone and testosterone ...... 3A4 in human liver microsomes.
@ast
Progesterone and testosterone ...... 3A4 in human liver microsomes.
@en
Progesterone and testosterone ...... 3A4 in human liver microsomes.
@nl
P356
P1476
Progesterone and testosterone ...... 3A4 in human liver microsomes.
@en
P2093
P304
P356
10.1006/ABBI.1997.0302
P407
P577
1997-10-01T00:00:00Z