Therapeutic antibodies directed at G protein-coupled receptors - Wikidata - wikimedia - TriplyDB

Therapeutic antibodies directed at G protein-coupled receptors

Therapeutic antibodies directed at G protein-coupled receptors

http://www.wikidata.org/entity/Q34445135

about

Engineering therapeutic antibodies targeting G-protein-coupled receptors Targeting the Wnt pathways for therapies Multiple protein stationary phases: a review Opportunities for functional selectivity in GPCR antibodies G Protein-Coupled Receptor (GPCR) Expression in Native Cells: "Novel" endoGPCRs as Physiologic Regulators and Therapeutic Targets FcRn overexpression in transgenic mice results in augmented APC activity and robust immune response with increased diversity of induced antibodies Generation of a highly diverse panel of antagonistic chicken monoclonal antibodies against the GIP receptor i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4.Agarose Spot as a Comparative Method for in situ Analysis of Simultaneous Chemotactic Responses to Multiple Chemokines Expression of CXCL10 is associated with response to radiotherapy and overall survival in squamous cell carcinoma of the tongue.Plasma membrane proteomics of human breast cancer cell lines identifies potential targets for breast cancer diagnosis and treatment.Fully human antagonistic antibodies against CCR4 potently inhibit cell signaling and chemotaxis.Denatured G-protein coupled receptors as immunogens to generate highly specific antibodies.Selection of potential therapeutic human single-chain Fv antibodies against cholecystokinin-B/gastrin receptor by phage display technology.Stabilization of G protein-coupled receptors by point mutations.A combination of in vitro techniques for efficient discovery of functional monoclonal antibodies against human CXC chemokine receptor-2 (CXCR2)Phage display and hybridoma generation of antibodies to human CXCR2 yields antibodies with distinct mechanisms and epitopes.Functional Mimetics of the HIV-1 CCR5 Co-Receptor Displayed on the Surface of Magnetic Liposomes.IBC's 22nd Annual Antibody Engineering and 9th Annual Antibody Therapeutics International Conferences and the 2011 Annual Meeting of The Antibody Society, December 5-8, 2011, San Diego, CA.A parallel panning scheme used for selection of a GluA4-specific Fab targeting the ligand-binding domain.Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1 Somatostatin receptor staining in FFPE sections using a ligand derivative dye as an alternative to immunostaining.Generation and characterization of an antagonistic monoclonal antibody against an extracellular domain of mouse DP2 (CRTH2/GPR44) receptors for prostaglandin D2.Generation and characterization of rendomab-B1, a monoclonal antibody displaying potent and specific antagonism of the human endothelin B receptor Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway DNA immunization combined with scFv phage display identifies antagonistic GCGR specific antibodies and reveals new epitopes on the small extracellular loops Anti-coreceptor therapy drives selective T cell egress by suppressing inflammation-dependent chemotactic cues.Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment.Prefrontal Dopaminergic Mechanisms of Extinction in Adolescence Compared to Adulthood in Rats.Pharmacological modulation of chemokine receptor function.Are GPCRs still a source of new targets?Novel therapy based on camelid nanobodies.G protein-coupled receptors in rheumatology.New horizons in therapeutic antibody discovery: opportunities and challenges versus small-molecule therapeutics.Accelerating antibody discovery using transgenic animals overexpressing the neonatal Fc receptor as a result of augmented humoral immunity.Generation and characterization of monoclonal antibodies against human LGR6.Exploiting cancer's phenotypic guise against itself: targeting ectopically expressed peptide G-protein coupled receptors for lung cancer therapy.Opportunities for therapeutic antibodies directed at G-protein-coupled receptors.Comparative proteomic investigation of metastatic and non-metastatic osteosarcoma cells of human and canine origin Micro-scale and rapid expression screening of highly expressed and/or stable membrane protein variants in Saccharomyces cerevisiae.

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Therapeutic antibodies directed at G protein-coupled receptors

http://www.wikidata.org/entity/Q34445135

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Therapeutic antibodies directed at G protein-coupled receptors

@ast

Therapeutic antibodies directed at G protein-coupled receptors

@en

Therapeutic antibodies directed at G protein-coupled receptors

@nl

type

label

Therapeutic antibodies directed at G protein-coupled receptors

@ast

Therapeutic antibodies directed at G protein-coupled receptors

@en

Therapeutic antibodies directed at G protein-coupled receptors

@nl

prefLabel

Therapeutic antibodies directed at G protein-coupled receptors

@ast

Therapeutic antibodies directed at G protein-coupled receptors

@en

Therapeutic antibodies directed at G protein-coupled receptors

@nl

P1433

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P1433

Monoclonal Antibodies

P1476

Therapeutic antibodies directed at G protein-coupled receptors

@en

P2093

Catherine J Hutchings

http://www.w3.org/2001/XMLSchema#string

Markus Koglin

http://www.w3.org/2001/XMLSchema#string

P2860

Involvement of chemokine receptors in breast cancer metastasis

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

Constitutive dimerization of the G-protein coupled receptor, neurotensin receptor 1, reconstituted into phospholipid bilayers

A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer

Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes.

Recent developments in CCR2 antagonists

Cancer and the chemokine network

Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents

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594-606

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scholarly article

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10.4161/MABS.2.6.13420

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6

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P478

2

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2010-11-01T00:00:00Z

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46414088

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20864805

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P921

G protein-coupled receptor

P932

3011214

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