Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment.

Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment.

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http://www.wikidata.org/entity/Q37593696
Antibody Engineering & Therapeutics, the annual meeting of The Antibody Society December 7-10, 2015, San Diego, CA, USA.Generation of Recombinant Monoclonal Antibodies from Immunised Mice and Rabbits via Flow Cytometry and Sorting of Antigen-Specific IgG+ Memory B Cells.Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1DNA immunization combined with scFv phage display identifies antagonistic GCGR specific antibodies and reveals new epitopes on the small extracellular loopsDiscovery of functional antibodies targeting ion channels.New horizons in therapeutic antibody discovery: opportunities and challenges versus small-molecule therapeutics.Opportunities for therapeutic antibodies directed at G-protein-coupled receptors.A monoclonal antibody raised against a thermo-stabilised β1-adrenoceptor interacts with extracellular loop 2 and acts as a negative allosteric modulator of a sub-set of β1-adrenoceptors expressed in stable cell lines.Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges.A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies.
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Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment.

Item
http://www.wikidata.org/entity/Q37593696
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Monoclonal anti-β1-adrenergic ...... nce of β-arrestin recruitment.
@en
Monoclonal anti-β1-adrenergic ...... nce of β-arrestin recruitment.
@nl
type
label
Monoclonal anti-β1-adrenergic ...... nce of β-arrestin recruitment.
@en
Monoclonal anti-β1-adrenergic ...... nce of β-arrestin recruitment.
@nl
prefLabel
Monoclonal anti-β1-adrenergic ...... nce of β-arrestin recruitment.
@en
Monoclonal anti-β1-adrenergic ...... nce of β-arrestin recruitment.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Monoclonal anti-β1-adrenergic ...... nce of β-arrestin recruitment.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932