Active site mutant transgene confers tolerance to human beta-glucuronidase without affecting the phenotype of MPS VII mice.
about
A novel GUSB mutation in Brazilian terriers with severe skeletal abnormalities defines the disease as mucopolysaccharidosis VIIEnzyme replacement therapy on hypophosphatasia mouse model.Enhancement of drug delivery: enzyme-replacement therapy for murine Morquio A syndrome.Overcoming the blood-brain barrier with high-dose enzyme replacement therapy in murine mucopolysaccharidosis VII.New strategies for enzyme replacement therapy for lysosomal storage diseasesMutations and polymorphisms in GUSB gene in mucopolysaccharidosis VII (Sly Syndrome).Production of MPS VII mouse (Gus(tm(hE540A x mE536A)Sly)) doubly tolerant to human and mouse beta-glucuronidaseEnzyme therapy in mannose receptor-null mucopolysaccharidosis VII mice defines roles for the mannose 6-phosphate and mannose receptorsMucopolysaccharidosis VII in a Cat Caused by 2 Adjacent Missense Mutations in the GUSB GeneLong circulating enzyme replacement therapy rescues bone pathology in mucopolysaccharidosis VII murine model.Biochemical evidence for superior correction of neuronal storage by chemically modified enzyme in murine mucopolysaccharidosis VII.Chronic enzyme replacement therapy ameliorates neuropathology in alpha-mannosidosis miceAssessment of bone dysplasia by micro-CT and glycosaminoglycan levels in mouse models for mucopolysaccharidosis type I, IIIA, IVA, and VIIGlycosylation-independent targeting enhances enzyme delivery to lysosomes and decreases storage in mucopolysaccharidosis type VII miceDefining the pathway for Tat-mediated delivery of beta-glucuronidase in cultured cells and MPS VII mice.Central nervous system delivery of helper-dependent canine adenovirus corrects neuropathology and behavior in mucopolysaccharidosis type VII mice.Induction of tolerance to human arylsulfatase A in a mouse model of metachromatic leukodystrophy.
P2860
Q27335242-EEA63ABC-50C6-4911-9E6B-E8D181F39B64Q33610556-EB2A2E5F-D118-4121-81E6-2C7EB8E02924Q33930155-351A0D84-23BE-4B94-A393-7AEF2D06AA3BQ34078512-BFD72B85-A669-4011-A7EF-10B60E93E1EDQ34157148-3924D3E0-4AE3-43C2-9725-10E6295B5A5BQ34624792-6649B786-89AC-491B-AD03-59E0FCF066EDQ35032587-23FCA0EA-6C70-4A30-98BB-6BAB0A9ED0BEQ35108117-D6A52037-0048-4716-B4E5-FA623694BEB5Q36219704-4F72E082-E390-4BD1-9255-1F520E280BD4Q36240723-D12163FD-21E6-4FB4-963B-9DAF5A3725FAQ36342413-35E03B3D-6EFD-46E6-BC53-4DE60FAE7C45Q36410390-E1EA9FBB-B2BC-43D8-A51F-D4B8502EC0B9Q36674929-6195F339-B50A-4020-A08D-1C68AA1E70A5Q36853823-B595677A-88AB-4A74-AFB6-AFA9EB248BE3Q36982986-1C606FF6-3DDC-475E-8FE1-388AE5737C49Q38287249-BC48F065-7FE6-44C0-BDD2-9B6C41B81065Q42431886-E8AF1043-E13F-4A34-A83D-6A1F44E2322D
P2860
Active site mutant transgene confers tolerance to human beta-glucuronidase without affecting the phenotype of MPS VII mice.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Active site mutant transgene c ...... the phenotype of MPS VII mice.
@ast
Active site mutant transgene c ...... the phenotype of MPS VII mice.
@en
Active site mutant transgene c ...... the phenotype of MPS VII mice.
@nl
type
label
Active site mutant transgene c ...... the phenotype of MPS VII mice.
@ast
Active site mutant transgene c ...... the phenotype of MPS VII mice.
@en
Active site mutant transgene c ...... the phenotype of MPS VII mice.
@nl
prefLabel
Active site mutant transgene c ...... the phenotype of MPS VII mice.
@ast
Active site mutant transgene c ...... the phenotype of MPS VII mice.
@en
Active site mutant transgene c ...... the phenotype of MPS VII mice.
@nl
P2093
P2860
P356
P1476
Active site mutant transgene c ...... the phenotype of MPS VII mice
@en
P2093
P2860
P304
P356
10.1073/PNAS.051623698
P407
P50
P577
2001-02-13T00:00:00Z