Mismatch repair balances leading and lagging strand DNA replication fidelity.
about
Structure-function analysis of ribonucleotide bypass by B family DNA replicasesAprataxin resolves adenylated RNA–DNA junctions to maintain genome integrityNew insights into the mechanism of DNA mismatch repairExonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replicationLagging-strand replication shapes the mutational landscape of the genomeReplicative DNA polymerase δ but not ε proofreads errors in Cis and in TransA Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA StrandsEukaryotic genome instability in light of asymmetric DNA replicationIncreased and imbalanced dNTP pools symmetrically promote both leading and lagging strand replication infidelityRibonucleotides are signals for mismatch repair of leading-strand replication errorsDNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiaeDelivering nonidentical twinsEukaryotic Mismatch Repair in Relation to DNA ReplicationProcessing ribonucleotides incorporated during eukaryotic DNA replication.Mismatch Repair of DNA Replication Errors Contributes to Microevolution in the Pathogenic Fungus Cryptococcus neoformansHeterogeneous polymerase fidelity and mismatch repair bias genome variation and composition.Significant contribution of the 3'→5' exonuclease activity to the high fidelity of nucleotide incorporation catalyzed by human DNA polymerase ϵ.Expression of the mismatch repair gene hMLH1 is enhanced in non-small cell lung cancer with EGFR mutationsTracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation.Differences in genome-wide repeat sequence instability conferred by proofreading and mismatch repair defects.Quantifying the contributions of base selectivity, proofreading and mismatch repair to nuclear DNA replication in Saccharomyces cerevisiae.Human Pol ε-dependent replication errors and the influence of mismatch repair on their correction.Mechanisms of glycosylase induced genomic instabilityExonuclease 1 preferentially repairs mismatches generated by DNA polymerase αMutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair.Parkinson's disease: a complex interplay of mitochondrial DNA alterations and oxidative stress.Topoisomerase 1-mediated removal of ribonucleotides from nascent leading-strand DNAEvidence that processing of ribonucleotides in DNA by topoisomerase 1 is leading-strand specific.Sister chromatid telomere fusions, but not NHEJ-mediated inter-chromosomal telomere fusions, occur independently of DNA ligases 3 and 4.Mutation rates, spectra, and genome-wide distribution of spontaneous mutations in mismatch repair deficient yeast.Measuring ribonucleotide incorporation into DNA in vitro and in vivo.Stalled replication forks generate a distinct mutational signature in yeast.Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand.APOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context.Eukaryotic DNA Replication Fork.Family A and B DNA Polymerases in Cancer: Opportunities for Therapeutic Interventions.Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro.Aberrant methylation of mutL homolog 1 is associated with increased risk of non-small cell lung cancer.Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes.Studying Topoisomerase 1-Mediated Damage at Genomic Ribonucleotides.
P2860
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P2860
Mismatch repair balances leading and lagging strand DNA replication fidelity.
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Mismatch repair balances leading and lagging strand DNA replication fidelity.
@ast
Mismatch repair balances leading and lagging strand DNA replication fidelity.
@en
Mismatch repair balances leading and lagging strand DNA replication fidelity.
@nl
type
label
Mismatch repair balances leading and lagging strand DNA replication fidelity.
@ast
Mismatch repair balances leading and lagging strand DNA replication fidelity.
@en
Mismatch repair balances leading and lagging strand DNA replication fidelity.
@nl
prefLabel
Mismatch repair balances leading and lagging strand DNA replication fidelity.
@ast
Mismatch repair balances leading and lagging strand DNA replication fidelity.
@en
Mismatch repair balances leading and lagging strand DNA replication fidelity.
@nl
P2093
P2860
P50
P1433
P1476
Mismatch repair balances leading and lagging strand DNA replication fidelity
@en
P2093
Alan B Clark
Amy A Abdulovic-Cui
Jessica S Williams
Stephanie A Nick McElhinny
P2860
P304
P356
10.1371/JOURNAL.PGEN.1003016
P577
2012-10-11T00:00:00Z