Mismatch repair balances leading and lagging strand DNA replication fidelity. - Wikidata - wikimedia - TriplyDB

Mismatch repair balances leading and lagging strand DNA replication fidelity.

Mismatch repair balances leading and lagging strand DNA replication fidelity.

http://www.wikidata.org/entity/Q34446700

about

Structure-function analysis of ribonucleotide bypass by B family DNA replicases Aprataxin resolves adenylated RNA–DNA junctions to maintain genome integrity New insights into the mechanism of DNA mismatch repair Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication Lagging-strand replication shapes the mutational landscape of the genome Replicative DNA polymerase δ but not ε proofreads errors in Cis and in Trans A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands Eukaryotic genome instability in light of asymmetric DNA replication Increased and imbalanced dNTP pools symmetrically promote both leading and lagging strand replication infidelity Ribonucleotides are signals for mismatch repair of leading-strand replication errors DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae Delivering nonidentical twins Eukaryotic Mismatch Repair in Relation to DNA Replication Processing ribonucleotides incorporated during eukaryotic DNA replication.Mismatch Repair of DNA Replication Errors Contributes to Microevolution in the Pathogenic Fungus Cryptococcus neoformans Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition.Significant contribution of the 3'→5' exonuclease activity to the high fidelity of nucleotide incorporation catalyzed by human DNA polymerase ϵ.Expression of the mismatch repair gene hMLH1 is enhanced in non-small cell lung cancer with EGFR mutations Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation.Differences in genome-wide repeat sequence instability conferred by proofreading and mismatch repair defects.Quantifying the contributions of base selectivity, proofreading and mismatch repair to nuclear DNA replication in Saccharomyces cerevisiae.Human Pol ε-dependent replication errors and the influence of mismatch repair on their correction.Mechanisms of glycosylase induced genomic instability Exonuclease 1 preferentially repairs mismatches generated by DNA polymerase α Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair.Parkinson's disease: a complex interplay of mitochondrial DNA alterations and oxidative stress.Topoisomerase 1-mediated removal of ribonucleotides from nascent leading-strand DNA Evidence that processing of ribonucleotides in DNA by topoisomerase 1 is leading-strand specific.Sister chromatid telomere fusions, but not NHEJ-mediated inter-chromosomal telomere fusions, occur independently of DNA ligases 3 and 4.Mutation rates, spectra, and genome-wide distribution of spontaneous mutations in mismatch repair deficient yeast.Measuring ribonucleotide incorporation into DNA in vitro and in vivo.Stalled replication forks generate a distinct mutational signature in yeast.Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand.APOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context.Eukaryotic DNA Replication Fork.Family A and B DNA Polymerases in Cancer: Opportunities for Therapeutic Interventions.Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro.Aberrant methylation of mutL homolog 1 is associated with increased risk of non-small cell lung cancer.Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes.Studying Topoisomerase 1-Mediated Damage at Genomic Ribonucleotides.

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Mismatch repair balances leading and lagging strand DNA replication fidelity.

http://www.wikidata.org/entity/Q34446700

description

2012 nî lūn-bûn

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2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Mismatch repair balances leading and lagging strand DNA replication fidelity.

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Mismatch repair balances leading and lagging strand DNA replication fidelity.

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Mismatch repair balances leading and lagging strand DNA replication fidelity.

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type

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Mismatch repair balances leading and lagging strand DNA replication fidelity.

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Mismatch repair balances leading and lagging strand DNA replication fidelity.

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Mismatch repair balances leading and lagging strand DNA replication fidelity.

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prefLabel

Mismatch repair balances leading and lagging strand DNA replication fidelity.

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Mismatch repair balances leading and lagging strand DNA replication fidelity.

@en

Mismatch repair balances leading and lagging strand DNA replication fidelity.

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JOURNAL.PGEN.1003016

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Mismatch repair balances leading and lagging strand DNA replication fidelity

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Alan B Clark

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Amy A Abdulovic-Cui

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Jessica S Williams

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Stephanie A Nick McElhinny

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P2860

The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved

hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci

PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair

The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases

DNA mismatch repair: molecular mechanism, cancer, and ageing

A genomic code for nucleosome positioning

Yeast DNA polymerase epsilon participates in leading-strand DNA replication

Polymerase dynamics at the eukaryotic DNA replication fork

Structure of the human MutSalpha DNA lesion recognition complex

Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity.

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scholarly article

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10.1371/JOURNAL.PGEN.1003016

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10

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8

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Zachary Pursell

Thomas A Kunkel

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2012-10-11T00:00:00Z

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23071460

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3469411

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