Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
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GSK-3 Inhibitors: Preclinical and Clinical Focus on CNSIdentification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screenReduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's diseaseGlycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeuticsDistinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivoThe Rationale for Insulin Therapy in Alzheimer's DiseaseNeuronal response in Alzheimer's and Parkinson's disease: the effect of toxic proteins on intracellular pathwaysDeveloping therapeutic approaches to tau, selected kinases, and related neuronal protein targetsRescue from tau-induced neuronal dysfunction produces insoluble tau oligomersGSK-3β dysregulation contributes to parkinson's-like pathophysiology with associated region-specific phosphorylation and accumulation of tau and α-synucleinStructural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418Toxin-Induced Experimental Models of Learning and Memory ImpairmentThe protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathwayCHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survivalInvolvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3betaThe ups and downs of Wnt signaling in prevalent neurological disordersFRAT-2 preferentially increases glycogen synthase kinase 3 beta-mediated phosphorylation of primed sites, which results in enhanced tau phosphorylationLithium and bipolar mood disorder: the inositol-depletion hypothesis revisitedGSK3beta in ethanol neurotoxicityThe role of GSK3beta in the development of the central nervous systemOverexpression of 14-3-3z promotes tau phosphorylation at Ser262 and accelerates proteosomal degradation of synaptophysin in rat primary hippocampal neuronsMultiplex Brain Proteomic Analysis Revealed the Molecular Therapeutic Effects of Buyang Huanwu Decoction on Cerebral Ischemic Stroke MiceRole of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta signaling pathwayActivation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrilsEvidence for a role of glycogen synthase kinase-3 beta in rodent spermatogenesisEarly growth response 1 (Egr-1) regulates phosphorylation of microtubule-associated protein tau in mammalian brainA novel calcium-binding protein is associated with tau proteins in tauopathyNFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapyPS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutationsC3G regulates the size of the cerebral cortex neural precursor populationGSK3β Overexpression in Dentate Gyrus Neural Precursor Cells Expands the Progenitor Pool and Enhances Memory Skills.Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3.Post-ischemic estradiol treatment reduced glial response and triggers distinct cortical and hippocampal signaling in a rat model of cerebral ischemia.GSK-3: Functional Insights from Cell Biology and Animal Models.Mice lacking phosphatase PP2A subunit PR61/B'delta (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3beta.Glycogen synthase kinase-3 in the etiology and treatment of mood disorders.Is glycogen synthase kinase-3 a central modulator in mood regulation?Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy.Amyloid activates GSK-3beta to aggravate neuronal tauopathy in bigenic mice.Estradiol activates beta-catenin dependent transcription in neurons.
P2860
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P2860
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Decreased nuclear beta-catenin ...... ta conditional transgenic mice
@ast
Decreased nuclear beta-catenin ...... ta conditional transgenic mice
@en
Decreased nuclear beta-catenin ...... ta conditional transgenic mice
@nl
type
label
Decreased nuclear beta-catenin ...... ta conditional transgenic mice
@ast
Decreased nuclear beta-catenin ...... ta conditional transgenic mice
@en
Decreased nuclear beta-catenin ...... ta conditional transgenic mice
@nl
prefLabel
Decreased nuclear beta-catenin ...... ta conditional transgenic mice
@ast
Decreased nuclear beta-catenin ...... ta conditional transgenic mice
@en
Decreased nuclear beta-catenin ...... ta conditional transgenic mice
@nl
P2093
P2860
P356
P1433
P1476
Decreased nuclear beta-catenin ...... ta conditional transgenic mice
@en
P2093
P2860
P356
10.1093/EMBOJ/20.1.27
P407
P577
2001-01-01T00:00:00Z