Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy. - Wikidata - wikimedia - TriplyDB

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy.

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy.

http://www.wikidata.org/entity/Q30479525

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Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z Neurotrophic factors in Alzheimer’s disease: role of axonal transport SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds Using C. elegans to discover therapeutic compounds for ageing-associated neurodegenerative diseases The role of tau in neurodegenerative diseases and its potential as a therapeutic target Tau and tauopathies Tau mutant A152T, a risk factor for FTD/PSP, induces neuronal dysfunction and reduced lifespan independently of aggregation in a C. elegans Tauopathy model An ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of Caenorhabditis elegans dnc-1/dynactin 1 knockdown disrupts transport of autophagosomes and induces motor neuron degeneration Widespread protein aggregation as an inherent part of aging in C. elegans A genetic screening strategy identifies novel regulators of the proteostasis network The struggle by Caenorhabditis elegans to maintain proteostasis during aging and disease Tau physiology and pathomechanisms in frontotemporal lobar degeneration Mechanisms of aging-related proteinopathies in Caenorhabditis elegans The hexosamine signaling pathway: deciphering the "O-GlcNAc code"The homologous carboxyl-terminal domains of microtubule-associated protein 2 and TAU induce neuronal dysfunction and have differential fates in the evolution of neurofibrillary tangles In Vivo Modelling of ATP1A3 G316S-Induced Ataxia in C. elegans Using CRISPR/Cas9-Mediated Homologous Recombination Reveals Dominant Loss of Function Defects Animal models for Alzheimer's disease and frontotemporal dementia: a perspective Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau.Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice.Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy.MSUT2 is a determinant of susceptibility to tau neurotoxicity O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases.Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity Caenorhabditis elegans dnj-14, the orthologue of the DNAJC5 gene mutated in adult onset neuronal ceroid lipofuscinosis, provides a new platform for neuroprotective drug screening and identifies a SIR-2.1-independent action of resveratrol.Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.Three-repeat Tau 69 is a major tau isoform in laser-microdissected Pick bodies.Caenorhabditis elegans: a model to investigate oxidative stress and metal dyshomeostasis in Parkinson's disease Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation.Tauopathies with parkinsonism: clinical spectrum, neuropathologic basis, biological markers, and treatment options.PTL-1 regulates neuronal integrity and lifespan in C. elegans.Watching worms whither: modeling neurodegeneration in C. elegans.Transgenic models of Alzheimer's disease: learning from animals A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout.Neurotoxic effects of TDP-43 overexpression in C. elegans.Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management.The cytoskeleton in neurodegenerative diseases.

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P2860

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy.

http://www.wikidata.org/entity/Q30479525

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2003 nî lūn-bûn

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2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2003 թվականի հուլիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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Neurodegeneration and defectiv ...... is elegans model of tauopathy.

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Neurodegeneration and defectiv ...... is elegans model of tauopathy.

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Neurodegeneration and defectiv ...... is elegans model of tauopathy.

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Neurodegeneration and defectiv ...... is elegans model of tauopathy.

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Neurodegeneration and defectiv ...... is elegans model of tauopathy.

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Proceedings of the National Academy of Sciences of the United States of America

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Neurodegeneration and defectiv ...... is elegans model of tauopathy.

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P2093

Bin Zhang

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Brian C Kraemer

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Gerard D Schellenberg

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James H Thomas

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P2860

Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice

Confocal methods for Caenorhabditis elegans.

The Caenorhabditis elegans unc-31 gene affects multiple nervous system-controlled functions.

Caenorhabditis elegans mutants resistant to inhibitors of acetylcholinesterase.

Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

egl-4 acts through a transforming growth factor-beta/SMAD pathway in Caenorhabditis elegans to regulate multiple neuronal circuits in response to sensory cues.

Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia.

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100

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Caenorhabditis elegans

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187908

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