Structural basis of transcription inhibition by antibiotic streptolydigin.
about
Dissection of Pol II trigger loop function and Pol II activity-dependent control of start site selection in vivoThe Bridge Helix of RNA polymerase acts as a central nanomechanical switchboard for coordinating catalysis and substrate movementDirect observation of base-pair stepping by RNA polymeraseStructures of RNA polymerase-antibiotic complexesTagetitoxin inhibits RNA polymerase through trapping of the trigger loopResponse to Klyuyev and Vassylyev: on the mechanism of tagetitoxin inhibition of transcriptionThe RNA polymerase II trigger loop functions in substrate selection and is directly targeted by alpha-amanitinStructural basis for transcription inhibition by tagetitoxinThe carboxy-terminal coiled-coil of the RNA polymerase β′-subunit is the main binding site for Gre factorsCrystal structure of bacterial RNA polymerase bound with a transcription inhibitor proteinStructural basis of transcriptional pausing in bacteria.Transcription inhibition by the depsipeptide antibiotic salinamide ABacterial RNA Polymerase-DNA Interaction-The Driving Force of Gene Expression and the Target for Drug ActionAntibacterial Nucleoside-Analog Inhibitor of Bacterial RNA PolymeraseTemplated nucleoside triphosphate binding to a noncatalytic site on RNA polymerase regulates transcription.Trigger loop folding determines transcription rate of Escherichia coli's RNA polymeraseStepwise mechanism for transcription fidelityMolecular evolution of multisubunit RNA polymerases: structural analysisThe architecture of RNA polymerase fidelityIdentification of nocamycin biosynthetic gene cluster from Saccharothrix syringae NRRL B-16468 and generation of new nocamycin derivatives by manipulating gene cluster.Central role of the RNA polymerase trigger loop in intrinsic RNA hydrolysis.Molecular basis of RNA polymerase promoter specificity switch revealed through studies of Thermus bacteriophage transcription regulatorConformational coupling, bridge helix dynamics and active site dehydration in catalysis by RNA polymerase.Biosynthesis of the RNA polymerase inhibitor streptolydigin in Streptomyces lydicus: tailoring modification of 3-methyl-aspartateStructural basis of transcription: role of the trigger loop in substrate specificity and catalysis.A unified model of transcription elongation: what have we learned from single-molecule experiments?Structural biology of bacterial RNA polymerase.Bridge helix and trigger loop perturbations generate superactive RNA polymerases.Elongation complexes of Thermus thermophilus RNA polymerase that possess distinct translocation conformations.Chemical synthesis enables biochemical and antibacterial evaluation of streptolydigin antibiotics.Total synthesis of (-)-tirandamycin C.Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II.CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.A non-canonical multisubunit RNA polymerase encoded by a giant bacteriophageStructural perspective on mutations affecting the function of multisubunit RNA polymerases.Bacterial Transcription as a Target for Antibacterial Drug Development.Mycobacterium tuberculosis is resistant to streptolydiginEnergetic and structural details of the trigger-loop closing transition in RNA polymerase II.Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism
P2860
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P2860
Structural basis of transcription inhibition by antibiotic streptolydigin.
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Structural basis of transcription inhibition by antibiotic streptolydigin.
@ast
Structural basis of transcription inhibition by antibiotic streptolydigin.
@en
Structural basis of transcription inhibition by antibiotic streptolydigin.
@nl
type
label
Structural basis of transcription inhibition by antibiotic streptolydigin.
@ast
Structural basis of transcription inhibition by antibiotic streptolydigin.
@en
Structural basis of transcription inhibition by antibiotic streptolydigin.
@nl
prefLabel
Structural basis of transcription inhibition by antibiotic streptolydigin.
@ast
Structural basis of transcription inhibition by antibiotic streptolydigin.
@en
Structural basis of transcription inhibition by antibiotic streptolydigin.
@nl
P2093
P1433
P1476
Structural basis of transcription inhibition by antibiotic streptolydigin
@en
P2093
Anna Perederina
Dmitry G Vassylyev
Dmitry Temiakov
Ekaterina Kashkina
Konstantin Severinov
Marina N Vassylyeva
Naohiro Matsugaki
Noriyuki Igarashi
Savva Zorov
Soichi Wakatsuki
P304
P356
10.1016/J.MOLCEL.2005.07.020
P577
2005-09-01T00:00:00Z