Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis. - Wikidata - wikimedia - TriplyDB

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

http://www.wikidata.org/entity/Q34452426

about

Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription.Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1.Taspase 1: A protease with many biological surprises.Bifunctional αHER2/CD3 RNA-engineered CART-like human T cells specifically eliminate HER2(+) gastric cancer Taspase1: a 'misunderstood' protease with translational cancer relevance.Unraveling the Activation Mechanism of Taspase1 which Controls the Oncogenic AF4-MLL Fusion Protein Disease-relevant signalling-pathways in head and neck cancer: Taspase1's proteolytic activity fine-tunes TFIIA function.

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P2860

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

http://www.wikidata.org/entity/Q34452426

description

2014 nî lūn-bûn

@nan

2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

@ast

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

@en

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

@nl

type

label

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

@ast

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

@en

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

@nl

prefLabel

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

@ast

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

@en

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

@nl

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Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.

@en

P2093

Brian A Van Tine

http://www.w3.org/2001/XMLSchema#string

Emily H Cheng

http://www.w3.org/2001/XMLSchema#string

James J Hsieh

http://www.w3.org/2001/XMLSchema#string

Patricia I Wang

http://www.w3.org/2001/XMLSchema#string

Toshinao Oyama

http://www.w3.org/2001/XMLSchema#string

Yiyu Dong

http://www.w3.org/2001/XMLSchema#string

P2860

The Hallmarks of Cancer

Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression

Cell cycle, CDKs and cancer: a changing paradigm

Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors

Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization

Uncleaved TFIIA is a substrate for taspase 1 and active in transcription

Taspase1 functions as a non-oncogene addiction protease that coordinates cancer cell proliferation and apoptosis

Comprehensive molecular portraits of human breast tumours

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

Cyclin E and survival in patients with breast cancer.

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1354-1366

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scholarly article

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10.1038/CR.2014.129

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11

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24

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2014-09-30T00:00:00Z

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266324626

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1022830980

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25267403

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4220155

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