Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels.
about
Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single geneA novel class of GABAA receptor subunit in tissues of the reproductive systemCloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retinaAutoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitusGAD2 on chromosome 10p12 is a candidate gene for human obesityStimulation of TM3 Leydig cell proliferation via GABA(A) receptors: a new role for testicular GABAGABA Signaling and Neuroactive Steroids in Adrenal Medullary Chromaffin CellsParacrine and autocrine interactions in the human islet: more than meets the eyeCommon defects of mitochondria and iron in neurodegeneration and diabetes (MIND): a paradigm worth exploringDesign Principles of Pancreatic Islets: Glucose-Dependent Coordination of Hormone PulsesNeurotransmitters act as paracrine signals to regulate insulin secretion from the human pancreatic islet.A high affinity glutamate/aspartate transport system in pancreatic islets of Langerhans modulates glucose-stimulated insulin secretionDifferential expression of glutamate receptor subtypes in rat pancreatic isletsPer-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretionPhosphorylation of serine residues 3, 6, 10, and 13 distinguishes membrane anchored from soluble glutamic acid decarboxylase 65 and is restricted to glutamic acid decarboxylase 65alphaStructural and functional characterization of the gamma 1 subunit of GABAA/benzodiazepine receptorsCombining antigen-based therapy with GABA treatment synergistically prolongs survival of transplanted ß-cells in diabetic NOD miceArtemisinins Target GABAA Receptor Signaling and Impair α Cell IdentityModels of glucagon secretion, their application to the analysis of the defects in glucagon counterregulation and potential extension to approximate glucagon action.Pancreatic network control of glucagon secretion and counterregulation.Amplification of pulsatile glucagon counterregulation by switch-off of alpha-cell-suppressing signals in streptozotocin-treated ratsRegulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic beta-cells.Phentolamine inhibits exocytosis of glucagon by Gi2 protein-dependent activation of calcineurin in rat pancreatic alpha -cells.Electrophysiological effects of GABA on cat pancreatic neurons.A -243A-->G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects.A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation.Glucotoxicity induces abnormal glucagon secretion through impaired insulin signaling in InR1G cellsATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic beta cellGlucose suppression of glucagon secretion: metabolic and calcium responses from alpha-cells in intact mouse pancreatic islets.Demonstration of GAD-65 as the main immunogenic isoform of glutamate decarboxylase in type 1 diabetes and determination of autoantibodies using a radioligand produced by eukaryotic expression.Positive regulation by GABA(B)R1 subunit of leptin expression through gene transactivation in adipocytes.Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells.GABA coordinates with insulin in regulating secretory function in pancreatic INS-1 β-cells.GABA's control of stem and cancer cell proliferation in adult neural and peripheral niches.The Zone Diet phenomenon: a closer look at the science behind the claims.A reappraisal of the blood glucose homeostat which comprehensively explains the type 2 diabetes mellitus-syndrome X complex.In intact islets interstitial GABA activates GABA(A) receptors that generate tonic currents in α-cells.Additive effects of miglitol and anagliptin on insulin-treated type 2 diabetes mellitus: a case study.Molecular physiology of vesicular glutamate transporters in the digestive system
P2860
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P2860
Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels.
description
1989 nî lūn-bûn
@nan
1989 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Glucose-inhibition of glucagon ...... AA-receptor chloride channels.
@ast
Glucose-inhibition of glucagon ...... AA-receptor chloride channels.
@en
Glucose-inhibition of glucagon ...... AA-receptor chloride channels.
@nl
type
label
Glucose-inhibition of glucagon ...... AA-receptor chloride channels.
@ast
Glucose-inhibition of glucagon ...... AA-receptor chloride channels.
@en
Glucose-inhibition of glucagon ...... AA-receptor chloride channels.
@nl
prefLabel
Glucose-inhibition of glucagon ...... AA-receptor chloride channels.
@ast
Glucose-inhibition of glucagon ...... AA-receptor chloride channels.
@en
Glucose-inhibition of glucagon ...... AA-receptor chloride channels.
@nl
P2093
P356
P1433
P1476
Glucose-inhibition of glucagon ...... AA-receptor chloride channels.
@en
P2093
P2888
P304
P356
10.1038/341233A0
P407
P577
1989-09-01T00:00:00Z
P6179
1034390863