Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells. - Wikidata - wikimedia - TriplyDB

Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells.

Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells.

http://www.wikidata.org/entity/Q33930246

about

CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells Membrane Potential and Calcium Dynamics in Beta Cells from Mouse Pancreas Tissue Slices: Theory, Experimentation, and Analysis Neurofunctional imaging of β-cell dynamics Paracrine and autocrine interactions in the human islet: more than meets the eye Design Principles of Pancreatic Islets: Glucose-Dependent Coordination of Hormone Pulses Combining antigen-based therapy with GABA treatment synergistically prolongs survival of transplanted ß-cells in diabetic NOD mice Improving the physiological realism of experimental models.Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication The neuronal K+Cl- co-transporter 2 (Slc12a5) modulates insulin secretion.Control of insulin secretion by cholinergic signaling in the human pancreatic islet.GABA coordinates with insulin in regulating secretory function in pancreatic INS-1 β-cells.Characteristic expressions of GABA receptors and GABA producing/transporting molecules in rat kidney Adaptive human CDKAL1 variants underlie hormonal response variations at the enteroinsular axis.In intact islets interstitial GABA activates GABA(A) receptors that generate tonic currents in α-cells.Recent progress in studies of factors that elicit pancreatic β-cell expansion GABAergic system in the endocrine pancreas: a new target for diabetes treatment.Mathematical modeling of heterogeneous electrophysiological responses in human β-cells Analysis of synaptic-like microvesicle exocytosis of B-cells using a live imaging technique.GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes Compartmentalization of GABA synthesis by GAD67 differs between pancreatic beta cells and neurons γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes.Increased Slc12a1 expression in β-cells and improved glucose disposal in Slc12a2 heterozygous mice Study of GABA in Healthy Volunteers: Pharmacokinetics and Pharmacodynamics.Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.Effect of Functional Bread Rich in Potassium, γ-Aminobutyric Acid and Angiotensin-Converting Enzyme Inhibitors on Blood Pressure, Glucose Metabolism and Endothelial Function: A Double-blind Randomized Crossover Clinical Trial SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells.A computational systems analysis of factors regulating α cell glucagon secretion.Intra-islet glucagon secretion and action in the regulation of glucose homeostasis.Fast synaptic inhibition in spinal sensory processing and pain control.UCP2 regulates the glucagon response to fasting and starvation Paracrine regulation of glucagon secretion: the β/α/δ model.T-cell autoantigens in the non-obese diabetic mouse model of autoimmune diabetes.Recent advances in pancreatic endocrine and exocrine secretion.Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?Autocrine regulation of insulin secretion.Advantages of an antagonist: bicuculline and other GABA antagonists.Minireview: intraislet regulation of insulin secretion in humans.The Amino Acid Transporters of the Glutamate/GABA-Glutamine Cycle and Their Impact on Insulin and Glucagon Secretion.ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: similar functions but reciprocal effects on secretion.New insights into the architecture of the islet of Langerhans: a focused cross-species assessment.

P2860

Q24298624-E9AF481E-5758-4C15-A2EF-9E83CEF93204 Q26777794-3FB84B9F-673C-4A7D-A4AB-83C0BB3509F1 Q26829645-C04FA436-D031-4FE4-995A-8829AED0A2C3 Q26852363-8ADE9C22-B6A0-4C39-99CD-4EF36ACB9305 Q27316153-CDE8ACD1-3537-4815-98D1-6B9ADDCCA883 Q28744642-5D789C39-8DC7-4C9B-87B0-5E35F9719ED7 Q30714211-2726E7C4-21F4-4ABA-B629-A33D2D4AE9E6 Q33673778-2D1BF55A-5F3A-4858-9FC8-076FAF22C363 Q33686739-AD521E1E-63E4-489E-B6A0-BD516502DFF1 Q33959750-4B13453D-8978-4154-933F-655A7592DE15 Q34059609-8C04B384-77CB-46CC-B3AC-27B64FF96EB0 Q34134655-D560D40A-0669-4346-A01B-FA913FFC2404 Q34183089-ADE3DE6D-04F3-4544-A935-695CCD77C193 Q34796718-E9C1951D-A715-4F42-BE9B-8A9A961689D2 Q35034557-532187F2-8BFD-4A67-8E70-F5D15AC124DD Q35067598-811C152C-7550-4FD4-9FBF-4B05A30EF191 Q35082155-7DFC64D3-1C51-45C9-A221-3A0989547FFB Q35087718-086241AD-0085-4E56-A761-DCED870846A7 Q35105197-427E58A8-0694-4DA3-AC21-E2A3E2824E2C Q35554433-0ECE9792-07C9-4DC1-B210-87B08C138D56 Q36013568-C10BE79B-82FE-486B-8A53-A24FA920BCE0 Q36215604-79C0F9ED-1FDA-440B-9AB9-7F1EF5E9FBE9 Q36265459-3D7811E8-5ED3-4CD4-9F18-47E35D8E6547 Q36284507-821EBBB5-3FDA-44E0-BD85-48C4F6F860A6 Q36299250-63410CB5-FDD4-4759-94DB-EE3892C30C2B Q36382533-7BCD81EA-145E-498B-91F3-8CE14B63FD3F Q36394674-74FD9627-7421-4E63-BB91-2B4A2886B207 Q36516806-E8D71296-9F9B-412C-9855-D06737C82855 Q36661675-C1D94930-5DB5-439A-BF0D-ABA8A4A25FF7 Q36796078-0CB481F0-F69D-48C9-80FB-64B431B7455D Q36810781-FCFF9932-9483-46CF-BE63-CCD888DCEF95 Q37805563-BD524E17-10C2-4911-AA2C-0EB3FECFF641 Q37903629-817BD3D1-82E1-4F7A-8B29-64E779FB8EF9 Q37913517-34D33BE5-6441-4D25-BAF5-3EF6FB7BDD9E Q38038660-F7D2FB88-AF06-4BFD-B9AE-571FD9C01DC8 Q38083098-77BD9E37-C2FF-409D-8EC5-52AFB79ED922 Q38163482-DFAFD799-6EF6-49A0-87A8-92E3AF605ADC Q38178663-074A0E24-72BD-4C71-92E9-0648E068F90C Q38218351-8256A987-334E-44C7-A993-4123C2CEE014 Q38555254-194101C7-8063-460F-86EB-C6718A18D1F7

P2860

Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells.

http://www.wikidata.org/entity/Q33930246

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Gamma-aminobutyric acid (GABA) ...... n human pancreatic beta-cells.

@ast

Gamma-aminobutyric acid (GABA) ...... n human pancreatic beta-cells.

@en

type

label

Gamma-aminobutyric acid (GABA) ...... n human pancreatic beta-cells.

@ast

Gamma-aminobutyric acid (GABA) ...... n human pancreatic beta-cells.

@en

prefLabel

Gamma-aminobutyric acid (GABA) ...... n human pancreatic beta-cells.

@ast

Gamma-aminobutyric acid (GABA) ...... n human pancreatic beta-cells.

@en

P1433

Q33930246-E66CEC50-A7E4-4BF0-BF40-332812B59C81

P1476

Q33930246-30E108D8-8921-4781-AE5F-C24A576869A5

P2093

Q33930246-2A57B6B6-DC76-442F-AA16-108A8D4F5D2F

Q33930246-66C67E72-9056-489B-A4DD-EFF7FC155B7A

Q33930246-94A6B329-7B23-42C1-8CC1-D80646EB0AC5

Q33930246-B476CE87-998D-43A2-AD71-E884AEC5CA09

Q33930246-DE74C596-CC26-4562-8848-C7CC87C34825

Q33930246-EC88ACA8-7CAA-42C4-ABB1-EDF487A3FD11

P2860

Q33930246-1299C07D-7CEC-41FA-A6CE-CC691C057F2A

Q33930246-15120EEC-59B1-4502-A4BD-794562838057

Q33930246-18273172-2F78-4391-A761-3B3818DE1D38

Q33930246-22A0C770-9A53-4D74-8EC8-BDAA1FB11D62

Q33930246-372D58A0-6E9C-4333-B405-571ED48E915A

Q33930246-50395275-6AC4-49E3-AA30-CA788CAD59B0

Q33930246-533798F4-CE1D-482E-A866-28269B233904

Q33930246-5BA8389D-D683-4D8D-BBFF-BCBB4B7F2181

Q33930246-690627DB-39EA-48DE-898D-A52783219013

Q33930246-7025155B-FCB3-4030-8462-DFB022F5C19F

P304

Q33930246-21C66B0A-5635-4514-AEE7-3D9093AA7FA7

P31

Q33930246-9F85DEEF-AC2A-45F5-A3A1-15A398CE3B75

P356

Q33930246-6DEC8365-161B-416E-AE31-82821F969F56

P407

Q33930246-14D4BF4D-7B21-4706-BF77-B45438FB92E2

P433

Q33930246-F949FC35-442C-4892-B981-FEEDE7F1E288

P478

Q33930246-B1129127-22A9-4465-87CA-45E2004263EF

P50

Q33930246-C0583F49-F66E-4056-9921-8E3FDB7541D2

P577

Q33930246-5EE1E5ED-C064-4CD1-821A-3ACE14673EFD

P5875

Q33930246-D9BD12EF-A0F2-4A22-8943-3D1B97C0EF10

P698

Q33930246-8781B70C-896F-4DC5-BE00-554EBE9F2CCB

P932

Q33930246-BC587F47-7A6C-41F1-BCB3-E642160CD8C9

P356

P1433

P1476

Gamma-aminobutyric acid (GABA) ...... n human pancreatic beta-cells.

@en

P2093

Anne Clark

http://www.w3.org/2001/XMLSchema#string

Jonathan N Walker

http://www.w3.org/2001/XMLSchema#string

Martin Bengtsson

http://www.w3.org/2001/XMLSchema#string

Matthias Braun

http://www.w3.org/2001/XMLSchema#string

Paul R Johnson

http://www.w3.org/2001/XMLSchema#string

Reshma Ramracheya

http://www.w3.org/2001/XMLSchema#string

P2860

The unique cytoarchitecture of human pancreatic islets has implications for islet cell function

R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion

Excitatory actions of gaba during development: the nature of the nurture

Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy.

Regulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic beta-cells.

Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels.

Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system.

Electrophysiology of stimulus-secretion coupling in human beta-cells.

Tonically active GABA A receptors: modulating gain and maintaining the tone.

Multiple exocytotic pathways in pancreatic beta cells.

P304

1694-1701

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.2337/DB09-0797

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

59

http://www.w3.org/2001/XMLSchema#string

P50

P577

2010-04-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

43299121

http://www.w3.org/2001/XMLSchema#string

P698

20413510

http://www.w3.org/2001/XMLSchema#string

P932

2889769

http://www.w3.org/2001/XMLSchema#string