Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis.

Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis.

Item
http://www.wikidata.org/entity/Q34454263
Research for new drugs for elimination of onchocerciasis in AfricaComparison of Doxycycline, Minocycline, Doxycycline plus Albendazole and Albendazole Alone in Their Efficacy against Onchocerciasis in a Randomized, Open-Label, Pilot TrialShort-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.The role of 'omics' in the quest to eliminate human filariasis.Anthelmintics - from discovery to resistanceSupergroup C Wolbachia, mutualist symbionts of filarial nematodes, have a distinct genome structure.Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.Repurposing strategies for tropical disease drug discovery.Wolbachia endosymbionts induce neutrophil extracellular trap formation in human onchocerciasis.Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library.Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis.Considerations for using minocycline vs doxycycline for treatment of canine heartworm disease.Combinations of registered drugs reduce treatment times required to deplete Wolbachia in the Litomosoides sigmodontis mouse model.Mining Filarial Genomes for Diagnostic and Therapeutic Targets.Alternative treatment strategies to accelerate the elimination of onchocerciasis.Adding "Filaricide" to the Gleevec Portfolio.
P2860

Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis.

Item
http://www.wikidata.org/entity/Q34454263
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Repurposing of approved drugs ...... asis and lymphatic filariasis.
@ast
Repurposing of approved drugs ...... asis and lymphatic filariasis.
@en
Repurposing of approved drugs ...... asis and lymphatic filariasis.
@nl
type
label
Repurposing of approved drugs ...... asis and lymphatic filariasis.
@ast
Repurposing of approved drugs ...... asis and lymphatic filariasis.
@en
Repurposing of approved drugs ...... asis and lymphatic filariasis.
@nl
prefLabel
Repurposing of approved drugs ...... asis and lymphatic filariasis.
@ast
Repurposing of approved drugs ...... asis and lymphatic filariasis.
@en
Repurposing of approved drugs ...... asis and lymphatic filariasis.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Repurposing of approved drugs ...... asis and lymphatic filariasis.
@en
P2093
P2860
P304
P31
P356
10.1016/J.IJPDDR.2014.09.001
P433
P478
P50
P577
P5875
P698
P921
P932