Nimbolide, a limonoid triterpene, inhibits growth of human colorectal cancer xenografts by suppressing the proinflammatory microenvironment
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Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its developmentReview on molecular and chemopreventive potential of nimbolide in cancerNimbolide targets BCL2 and induces apoptosis in preclinical models of Waldenströms macroglobulinemia.Nimbolide upregulates RECK by targeting miR-21 and HIF-1α in cell lines and in a hamster oral carcinogenesis modelEssential oils and their constituents as anticancer agents: a mechanistic view.The roles of endoplasmic reticulum overload response induced by HCV and NS4B protein in human hepatocyte viability and virus replication.MiR-1180 promotes apoptotic resistance to human hepatocellular carcinoma via activation of NF-κB signaling pathwayBigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species.Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression.Nimbolide Inhibits Nuclear Factor-КB Pathway in Intestinal Epithelial Cells and Macrophages and Alleviates Experimental Colitis in Mice.Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition.Preclinical evaluation of the supercritical extract of azadirachta indica (neem) leaves in vitro and in vivo on inhibition of prostate cancer tumor growthTerpinen-4-ol inhibits colorectal cancer growth via reactive oxygen species.Nimbolide reduces CD44 positive cell population and induces mitochondrial apoptosis in pancreatic cancer cells.A small molecule, (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol suppresses tumor growth via inhibition of IkappaB kinase β in colorectal cancer in vivo and in vitro.Masticadienonic and 3α-OH Masticadienoic Acids Induce Apoptosis and Inhibit Cell Proliferation and Tumor Growth in Prostate Cancer Xenografts in Vivo.Pinus Roxburghii essential oil anticancer activity and chemical composition evaluation.Network Pharmacology-Based Validation of Caveolin-1 as a Key Mediator of Ai Du Qing Inhibition of Drug Resistance in Breast CancerTerpenes from essential oils and hydrolate of triggered apoptotic events dependent on caspases activation and PARP cleavage in human colon cancer cells through decreased protein expressions
P2860
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P2860
Nimbolide, a limonoid triterpene, inhibits growth of human colorectal cancer xenografts by suppressing the proinflammatory microenvironment
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2013 nî lūn-bûn
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2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
Nimbolide, a limonoid triterpe ...... oinflammatory microenvironment
@ast
Nimbolide, a limonoid triterpe ...... oinflammatory microenvironment
@en
Nimbolide, a limonoid triterpe ...... oinflammatory microenvironment
@nl
type
label
Nimbolide, a limonoid triterpe ...... oinflammatory microenvironment
@ast
Nimbolide, a limonoid triterpe ...... oinflammatory microenvironment
@en
Nimbolide, a limonoid triterpe ...... oinflammatory microenvironment
@nl
prefLabel
Nimbolide, a limonoid triterpe ...... oinflammatory microenvironment
@ast
Nimbolide, a limonoid triterpe ...... oinflammatory microenvironment
@en
Nimbolide, a limonoid triterpe ...... oinflammatory microenvironment
@nl
P2093
P2860
P1476
Nimbolide, a limonoid triterpe ...... oinflammatory microenvironment
@en
P2093
Bharat B Aggarwal
Dhanya R Sethumadhavan
Mangalam S Nair
Sahdeo Prasad
Subash C Gupta
Yin-Yuan Mo
P2860
P304
P356
10.1158/1078-0432.CCR-13-0080
P407
P577
2013-06-13T00:00:00Z