The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene.
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Krüppel-like factor 4 regulates genetic stability in mouse embryonic fibroblastsProtein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damageFOXP3 up-regulates p21 expression by site-specific inhibition of histone deacetylase 2/histone deacetylase 4 association to the locusConnexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response.Mammalian Krüppel-like factors in health and diseasesPrognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migrationDirect cell reprogramming is a stochastic process amenable to accelerationThe diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiologyCancer Stem Cell Hierarchy in Glioblastoma MultiformeThe Role of Krüppel-like Factor 4 in Renal FibrosisThe impact of cellular senescence in cancer therapy: is it true or not?Regulation of an inflammatory disease: Krüppel-like factors and atherosclerosisTechniques of Human Embryonic Stem Cell and Induced Pluripotent Stem Cell DerivationThe cell cycle as a brake for β-cell regeneration from embryonic stem cellsThe oncogene c-Jun impedes somatic cell reprogrammingDeficiency of the Kruppel-like factor KLF4 correlates with increased cell proliferation and enhanced skin tumorigenesisAblation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressorKrüppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor beta-mediated, not by retinoic acid receptor alpha-mediated, phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cellsKrüppel-like factor 4 interacts with p300 to activate mitofusin 2 gene expression induced by all-trans retinoic acid in VSMCsConditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cellsMicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell linesLinking the p53 tumour suppressor pathway to somatic cell reprogrammingInducible pluripotent stem cells: not quite ready for prime time?Cyclosporine up-regulates Krüppel-like factor-4 (KLF4) in vascular smooth muscle cells and drives phenotypic modulation in vivo.p21 in cancer: intricate networks and multiple activitiesConditional deletion of Krüppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injuryMultiple repressor pathways contribute to phenotypic switching of vascular smooth muscle cells.Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis.Identification of Pou5f1, Sox2, and Nanog downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data.Functional identification of LRF as an oncogene that bypasses RASV12-induced senescence via upregulation of CYCLIN E.Linking incomplete reprogramming to the improved pluripotency of murine embryonal carcinoma cell-derived pluripotent stem cellsA human functional protein interaction network and its application to cancer data analysisThe Transcription Regulator Krüppel-Like Factor 4 and Its Dual Roles of Oncogene in Glioblastoma and Tumor Suppressor in Neuroblastoma.KLF4 is regulated by RAS/RAF/MEK/ERK signaling through E2F1 and promotes melanoma cell growth.Genetic deletion of Klf4 in the mouse intestinal epithelium ameliorates dextran sodium sulfate-induced colitis by modulating the NF-κB pathway inflammatory responseKruppel-like factor 4 inhibits epithelial-to-mesenchymal transition through regulation of E-cadherin gene expressionMCC-555-induced NAG-1 expression is mediated in part by KLF4.Fatty acid-binding protein 5 and PPARbeta/delta are critical mediators of epidermal growth factor receptor-induced carcinoma cell growthZebrafish krüppel-like factor 4a represses intestinal cell proliferation and promotes differentiation of intestinal cell lineages.miR-2909-mediated regulation of KLF4: a novel molecular mechanism for differentiating between B-cell and T-cell pediatric acute lymphoblastic leukemias
P2860
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P2860
The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene.
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The KLF4 tumour suppressor is ...... a context-dependent oncogene.
@ast
The KLF4 tumour suppressor is ...... a context-dependent oncogene.
@en
The KLF4 tumour suppressor is ...... a context-dependent oncogene.
@nl
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label
The KLF4 tumour suppressor is ...... a context-dependent oncogene.
@ast
The KLF4 tumour suppressor is ...... a context-dependent oncogene.
@en
The KLF4 tumour suppressor is ...... a context-dependent oncogene.
@nl
prefLabel
The KLF4 tumour suppressor is ...... a context-dependent oncogene.
@ast
The KLF4 tumour suppressor is ...... a context-dependent oncogene.
@en
The KLF4 tumour suppressor is ...... a context-dependent oncogene.
@nl
P356
P1433
P1476
The KLF4 tumour suppressor is ...... a context-dependent oncogene.
@en
P2093
Benjamin D Rowland
Daniel S Peeper
P2888
P304
P356
10.1038/NCB1314
P577
2005-11-01T00:00:00Z
P5875
P6179
1051068549