The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression. - Wikidata - wikimedia - TriplyDB

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

http://www.wikidata.org/entity/Q34463632

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The Janus kinases (Jaks)SCF(HOS) ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-alpha receptor Principles of interleukin (IL)-6-type cytokine signalling and its regulation Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus Basal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motif Hemagglutinin of Influenza A Virus Antagonizes Type I Interferon (IFN) Responses by Inducing Degradation of Type I IFN Receptor 1 Ubiquitination-mediated regulation of interferon responses Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome Regulation of interleukin-10 receptor ubiquitination and stability by beta-TrCP-containing ubiquitin E3 ligase A novel requirement for Janus kinases as mediators of drug resistance induced by fibroblast growth factor-2 in human cancer cells TYK2 kinase activity is required for functional type I interferon responses in vivo Jak2 is a negative regulator of ubiquitin-dependent endocytosis of the growth hormone receptor Kinase Inactive Tyrosine Kinase (Tyk2) Supports Differentiation of Brown Fat Cells.Localized delivery of interferon-β by Lactobacillus exacerbates experimental colitis Human metapneumovirus inhibits IFN-β signaling by downregulating Jak1 and Tyk2 cellular levels.Structural basis of recognition of interferon-α receptor by tyrosine kinase 2 Jak3-independent trafficking of the common gamma chain receptor subunit: chaperone function of Jaks revisited.Interferon-stimulated genes: a complex web of host defenses.The wild-derived inbred mouse strain SPRET/Ei is resistant to LPS and defective in IFN-beta production.Jak/STAT pathways in cytokine signaling and myeloproliferative disorders: approaches for targeted therapies.West Nile virus infection induces depletion of IFNAR1 protein levels Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2 Tyrosine phosphorylation of protein kinase D2 mediates ligand-inducible elimination of the Type 1 interferon receptor.Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signaling Impairment of type I but not type III IFN signaling by hepatitis C virus infection influences antiviral responses in primary human hepatocytes A new modality for immunosuppression: targeting the JAK/STAT pathway.In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity Ubiquitin chains in the ladder of MAPK signaling.Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies Genetics of SLE: functional relevance for monocytes/macrophages in disease Ligand-independent pathway that controls stability of interferon alpha receptor The role of Janus kinases in haemopoiesis and haematological malignancy.Hepatitis B virus X protein inhibits extracellular IFN-α-mediated signal transduction by downregulation of type I IFN receptor.Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasome Separate endocytic pathways regulate IL-5 receptor internalization and signaling Hematopoietic cytokine receptor signaling.Dietary apigenin potentiates the inhibitory effect of interferon-α on cancer cell viability through inhibition of 26S proteasome-mediated interferon receptor degradation Regulation of prolactin receptor levels and activity in breast cancer Biology and significance of the JAK/STAT signalling pathways.

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The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

http://www.wikidata.org/entity/Q34463632

description

2003 nî lūn-bûn

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2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի փետրվարին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

@ast

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

@en

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

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type

label

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

@ast

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

@en

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

@nl

prefLabel

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

@ast

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

@en

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

@nl

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P1433

The EMBO Journal

P1476

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression

@en

P2093

Elisabetta Dondi

http://www.w3.org/2001/XMLSchema#string

Josiane Ragimbeau

http://www.w3.org/2001/XMLSchema#string

Pierre Eid

http://www.w3.org/2001/XMLSchema#string

P2860

Functional role of type I and type II interferons in antiviral defense

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

Interleukin-10 and the interleukin-10 receptor

Identification and functional characterization of a second chain of the interleukin-10 receptor complex.

EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif

A new member of the cytokine receptor gene family maps on chromosome 21 at less than 35 kb from IFNAR

The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor

How cells respond to interferons

The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor

Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transduction

P304

537-547

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scholarly article

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10.1093/EMBOJ/CDG038

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P433

3

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P478

22

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Sandra Pellegrini

Andrés Alcover

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2003-02-01T00:00:00Z

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10928020

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P698

12554654

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P932

140723

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