Identification of an Aurora kinase inhibitor specific for the Aurora B isoform. - Wikidata - wikimedia - TriplyDB

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

http://www.wikidata.org/entity/Q34464172

about

Use of rodents as models of human diseases 3,6,2',4',5'-Pentahydroxyflavone, an orally bioavailable multiple protein kinase inhibitor, overcomes gefitinib resistance in non-small cell lung cancer.A phase 1 dose escalation study of BI 831266, an inhibitor of Aurora kinase B, in patients with advanced solid tumors Targeting epidermal fatty acid binding protein for treatment of experimental autoimmune encephalomyelitis.Tubulin Beta3 Serves as a Target of HDAC3 and Mediates Resistance to Microtubule-Targeting Drugs.Quercetin suppresses lung cancer growth by targeting Aurora B kinase.Inhibition of Aurora-B suppresses osteosarcoma cell migration and invasion.A derivative of chrysin suppresses two-stage skin carcinogenesis by inhibiting mitogen- and stress-activated kinase 1.Effective Concentration of a Multikinase Inhibitor within Bone Marrow Correlates with In Vitro Cell Killing in Therapy-Resistant Chronic Myeloid Leukemia.Dose selection for the investigational anticancer agent alisertib (MLN8237): Pharmacokinetics, pharmacodynamics, and exposure-safety relationships.APIO-EE-9 is a novel Aurora A and B antagonist that suppresses esophageal cancer growth in a PDX mouse model.

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P2860

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

http://www.wikidata.org/entity/Q34464172

description

2012 nî lūn-bûn

@nan

2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

@ast

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

@en

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

@nl

type

label

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

@ast

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

@en

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

@nl

prefLabel

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

@ast

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

@en

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

@nl

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0008-5472.CAN-12-2784

P1433

Cancer Research

P1476

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform

@en

P2093

Ann M Bode

http://www.w3.org/2001/XMLSchema#string

Cong Peng

http://www.w3.org/2001/XMLSchema#string

Do Young Lim

http://www.w3.org/2001/XMLSchema#string

Dong Joon Kim

http://www.w3.org/2001/XMLSchema#string

Haitao Li

http://www.w3.org/2001/XMLSchema#string

Hua Xie

http://www.w3.org/2001/XMLSchema#string

Jian Ding

http://www.w3.org/2001/XMLSchema#string

Kanamata Reddy

http://www.w3.org/2001/XMLSchema#string

Mee-Hyun Lee

http://www.w3.org/2001/XMLSchema#string

Ronald A Lubet

http://www.w3.org/2001/XMLSchema#string

P2860

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis

Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

Overexpression of an Aurora-C kinase-deficient mutant disrupts the Aurora-B/INCENP complex and induces polyploidy

Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells

The cellular geography of aurora kinases

Aurora B expression directly correlates with prostate cancer malignancy and influence prostate cell proliferation.

A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo.

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716-724

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scholarly article

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10.1158/0008-5472.CAN-12-2784

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2

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