The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias - Wikidata - wikimedia - TriplyDB

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

http://www.wikidata.org/entity/Q34465221

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Linking Pesticide Exposure with Pediatric Leukemia: Potential Underlying Mechanisms ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia Redefining ALL classification: toward detecting high-risk ALL and implementing precision medicine Childhood acute lymphoblastic leukemia: Integrating genomics into therapy Hypermutation takes the driver's seat Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia.Age-related somatic mutations in the cancer genome The molecular mechanics of mixed lineage leukemia.Translating RNA sequencing into clinical diagnostics: opportunities and challenges.cnvCurator: an interactive visualization and editing tool for somatic copy number variations.Dysregulation of the DNA Damage Response and KMT2A Rearrangement in Fetal Liver Hematopoietic Cells.Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development.MLL leukemia induction by genome editing of human CD34+ hematopoietic cells.Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.Childhood hematologic cancer and residential proximity to oil and gas development.MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199.Identification of Novel Fusion Genes in Testicular Germ Cell Tumors.Distinctive genotypes in infants with T-cell acute lymphoblastic leukaemia.Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer.Exploiting the Epigenome to Control Cancer-Promoting Gene-Expression Programs.Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia.Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.The role of the RAS pathway in iAMP21-ALL.Deciphering KRAS and NRAS mutated clone dynamics in MLL-AF4 paediatric leukaemia by ultra deep sequencing analysis.Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations.MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches.Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes.MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation MEK1 is required for the development of NRAS-driven leukemia.The neoepitope landscape in pediatric cancers.Chemical exposure and infant leukaemia: development of an adverse outcome pathway (AOP) for aetiology and risk assessment research.Identification of SETD2-NF1 fusion gene in a pediatric spindle cell tumor with the chromosomal translocation t(3;17)(p21;q12).Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance BET inhibitor resistance emerges from leukaemia stem cells.Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development.

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The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

http://www.wikidata.org/entity/Q34465221

description

2015 nî lūn-bûn

@nan

2015 թուականի Մարտին հրատարակուած գիտական յօդուած

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2015 թվականի մարտին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

@ast

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

@en

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

@nl

type

label

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

@ast

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

@en

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

@nl

prefLabel

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

@ast

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

@en

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

@nl

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Nature Genetics

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The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

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Albert Chetcuti

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Amanda Larson Gedman

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Amanda Rush

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Bhavin Vadodaria

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Charles Lu

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Cheng Cheng

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Ching-Hon Pui

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Daniel Catchpoole

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Debbie Payne-Turner

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Deqing Pei

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P2860

Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

The FoldX web server: an online force field

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma

Recurring mutations found by sequencing an acute myeloid leukemia genome

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330-337

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scholarly article

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10.1038/NG.3230

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4

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47

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Charles G. Mullighan

Linda Holmfeldt

Anna K Hagström-Andersson

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2015-03-02T00:00:00Z

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273064491

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25730765

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4553269

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