Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond
about
Update on rational targeted therapy in AMLRevisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemiaEpigenetics in Cancer: A Hematological PerspectiveTargeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.The molecular mechanics of mixed lineage leukemia.Design of a fluorescent ligand targeting the S-adenosylmethionine binding site of the histone methyltransferase MLL1.CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements.Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel.The Role of Histone Protein Modifications and Mutations in Histone Modifiers in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia.SAM/SAH Analogs as Versatile Tools for SAM-Dependent Methyltransferases.Chemical exposure and infant leukaemia: development of an adverse outcome pathway (AOP) for aetiology and risk assessment research.The upstreams and downstreams of H3K79 methylation by DOT1L.Roles and epigenetic regulation of epithelial-mesenchymal transition and its transcription factors in cancer initiation and progression.Targeting human SET1/MLL family of proteins.SET/MLL family proteins in hematopoiesis and leukemia.Transcriptional Addiction in Cancer.Dysregulation of BCL-2 family proteins by leukemia fusion genes.Recurrent translocation t(10;17)(p15;q21) in minimally differentiated acute myeloid leukemia results in ZMYND11/MBTD1 fusion.KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway.Controlled inhibition of methyltransferases using photoswitchable peptidomimetics: towards an epigenetic regulation of leukemia.HOXA-activated early T-cell progenitor acute lymphoblastic leukemia: predictor of poor outcome?Cancer epigenetics: Reading the future of leukaemia.SALL4 as a transcriptional and epigenetic regulator in normal and leukemic hematopoiesis.Transcriptional activator DOT1L putatively regulates human embryonic stem cell differentiation into the cardiac lineage.
P2860
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P2860
Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond
description
2015 nî lūn-bûn
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2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
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2015年论文
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2015年论文
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name
Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond
@ast
Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond
@en
type
label
Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond
@ast
Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond
@en
prefLabel
Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond
@ast
Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond
@en
P2860
P1476
Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond
@en
P2093
Scott A Armstrong
P2860
P304
P356
10.1016/J.EXPHEM.2015.05.012
P577
2015-06-25T00:00:00Z