Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.
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Targeting the PI3K/Akt cell survival pathway to induce cell death of HIV-1 infected macrophages with alkylphospholipid compoundsRoles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targettingMyc stabilization in response to estrogen and phospholipase D in MCF-7 breast cancer cellsThe PI3K-PDK1 connection: more than just a road to PKBTwo novel phosphorylation sites on FKHR that are critical for its nuclear exclusionAkt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapyOpposite regulation of XIAP and Smac/DIABLO in the rat endometrium in response to 17beta-estradiol at estrusTargeting the insulin-like growth factor pathway in hepatocellular carcinomaMetformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathySelective attenuation of metabolic branch of insulin receptor down-signaling by high glucose in a hepatoma cell line, HepG2 cellsA-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3betaSuppression of androgen receptor-mediated transactivation and cell growth by the glycogen synthase kinase 3 beta in prostate cellsAKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitroInsulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase AktRequirement for Akt (protein kinase B) in insulin-induced activation of glycogen synthase and phosphorylation of 4E-BP1 (PHAS-1)A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification.Glucose metabolism-related protein 1 (GMRP1) regulates pancreatic beta cell proliferation and apoptosis via activation of Akt signalling pathway in rats and miceProliferation and apoptosis in mammary epithelium during the rat oestrous cycleGlycogen synthase kinase 3beta-mediated apoptosis of primary cortical astrocytes involves inhibition of nuclear factor kappaB signalingCross-talk between protein kinases Czeta and B in cyclic AMP-mediated sodium taurocholate co-transporting polypeptide translocation in hepatocytesSWAP-70 regulates c-kit-induced mast cell activation, cell-cell adhesion, and migrationEthanol impairs insulin-stimulated neuronal survival in the developing brain: role of PTEN phosphatase.Akt-PDK1 complex mediates epidermal growth factor-induced membrane protrusion through Ral activation.Development of sulfonamide AKT PH domain inhibitors.Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP).Discovery of a novel class of AKT pleckstrin homology domain inhibitors.Transcriptional repression by RB-E2F and regulation of anchorage-independent survival.Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblastsMolecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor.Signal transduction pathways that regulate eukaryotic protein synthesis.Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-Kinase/Akt pathway.Quantitative phosphoproteome on the silkworm (Bombyx mori) cells infected with baculovirusNovel inhibitors of AKT: assessment of a different approach targeting the pleckstrin homology domain.Glycogen synthase kinase 3beta contributes to proliferation of arterial smooth muscle cells in pulmonary hypertension.Signaling pathways mediating insulin-stimulated glucose transport.Mechanism of protein kinase B activation by cyclic AMP-dependent protein kinase.Cell-extracellular matrix interactions stimulate the AP-1 transcription factor in an integrin-linked kinase- and glycogen synthase kinase 3-dependent mannerAltered extracellular signal-regulated kinase signaling and glycogen metabolism in skeletal muscle from p90 ribosomal S6 kinase 2 knockout miceElevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytesIn vitro and in vivo activity of novel small-molecule inhibitors targeting the pleckstrin homology domain of protein kinase B/AKT.
P2860
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P2860
Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Essential role for protein kin ...... minant-negative mutant of PKB.
@ast
Essential role for protein kin ...... minant-negative mutant of PKB.
@en
Essential role for protein kinase B
@nl
type
label
Essential role for protein kin ...... minant-negative mutant of PKB.
@ast
Essential role for protein kin ...... minant-negative mutant of PKB.
@en
Essential role for protein kinase B
@nl
prefLabel
Essential role for protein kin ...... minant-negative mutant of PKB.
@ast
Essential role for protein kin ...... minant-negative mutant of PKB.
@en
Essential role for protein kinase B
@nl
P2093
P356
P1476
Essential role for protein kin ...... minant-negative mutant of PKB.
@en
P2093
Burgering BM
de Bruyn KM
de Vries-Smits AM
van Lint J
van Weeren PC
P304
13150-13156
P356
10.1074/JBC.273.21.13150
P407
P577
1998-05-01T00:00:00Z