Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.

Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.

Item

http://www.wikidata.org/entity/Q34468117

Q34468117

about

Emerging concepts in the immunopathogenesis of AIDS CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 +/- IL-15 CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects Limited durability of viral control following treated acute HIV infection Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "RecycleSpot"Inefficient cytotoxic T lymphocyte-mediated killing of HIV-1-infected cells in vivo T-cell therapies for HIV Ex vivo SIV-specific CD8 T cell responses in heterozygous animals are primarily directed against peptides presented by a single MHC haplotype Latent Membrane Protein 1 as a molecular adjuvant for single-cycle lentiviral vaccines Dendritic cells reveal a broad range of MHC class I epitopes for HIV-1 in persons with suppressed viral load on antiretroviral therapy Association of differentiation state of CD4+ T cells and disease progression in HIV-1 perinatally infected children Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection Inhibitory potential of subpopulations of CD8+ T cells in HIV-1-infected elite suppressors Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells CTL epitope distribution patterns in the Gag and Nef proteins of HIV-1 from subtype A infected subjects in Kenya: use of multiple peptide sets increases the detectable breadth of the CTL response.Vaccine design for CD8 T lymphocyte responses CD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesis Enhanced detection of human immunodeficiency virus type 1 (HIV-1) Nef-specific T cells recognizing multiple variants in early HIV-1 infection.The intracellular detection of MIP-1beta enhances the capacity to detect IFN-gamma mediated HIV-1-specific CD8 T-cell responses in a flow cytometric setting providing a sensitive alternative to the ELISPOT.Virus-specific CD8+ T-cell responses better define HIV disease progression than HLA genotype Fully differentiated HIV-1 specific CD8+ T effector cells are more frequently detectable in controlled than in progressive HIV-1 infection.Synonymous substitution rates predict HIV disease progression as a result of underlying replication dynamics HIV-1 group M conserved elements vaccine.Peptide impurities in commercial synthetic peptides and their implications for vaccine trial assessment Broad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads.Expression of HIV-1 antigens in plants as potential subunit vaccines Abundance of early functional HIV-specific CD8+ T cells does not predict AIDS-free survival time.Immunity to HIV-1 is influenced by continued natural exposure to exogenous virus.Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical status Dynamic correlation between intrahost HIV-1 quasispecies evolution and disease progression.Host HLA B*allele-associated multi-clade Gag T-cell recognition correlates with slow HIV-1 disease progression in antiretroviral therapy-naïve Ugandans.In vitro priming recapitulates in vivo HIV-1 specific T cell responses, revealing rapid loss of virus reactive CD4 T cells in acute HIV-1 infection.Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.Epitope mapping of HIV-specific CD8+ T cells in a cohort dominated by clade A1 infection.Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequences Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic.Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques.

P2860

Q22241984-21256258-8EDA-44E8-A964-2966733DF829 Q22242965-FE897DEC-B909-4C85-BA2C-12A99614C7CA Q24538985-98D30F1D-83AE-4A9D-9F1D-7CFECA527488 Q24792056-99E20D5B-F990-42F3-9DB7-26284278618B Q24798701-4E1ED336-AC09-4AAD-8B85-20094FAECAF4 Q24804986-69EEB304-BBB7-4549-86BE-E956C80DA882 Q24814428-F77E1AA2-050E-4D73-AE8A-DC41AE62AA7B Q25255777-394D619F-20D5-490A-837E-17713EDF4C2A Q26866079-BF3CB4AC-88AA-4E89-9EB9-7A3A7D4CF8E3 Q27322650-4341DFE7-C464-401C-AF4C-E269BCCF9A4A Q27497985-9934D312-39D8-46C5-B97D-99E2220D9F68 Q28475576-2F6B325B-2381-4D1F-8156-4B540BF48522 Q28478811-256AAD15-6673-4364-BE8A-04BFADFFE66F Q28480902-DA3BA807-1462-4D6D-A5B3-511D68258C92 Q28710569-914E1DAE-93B4-4D5F-BED8-51AD203CF099 Q28754733-92C1FCC9-26C2-4A1C-9775-EA04CE2DD9E6 Q29616205-32C9FD56-3E8C-42CA-9926-318B1D74ACE4 Q30353953-94BD920E-5D6D-4594-9DE0-F967B327610B Q30411492-6BB30C4F-E738-4FEF-9FEB-4F9161959912 Q30432007-DDC19589-A5A2-42C3-AD9C-529476546133 Q30479692-77FE0AA9-782E-42E7-A941-8ACB0F6E738C Q30484153-B0FE4737-9882-40EF-A072-4DF7E2618344 Q30494331-4E5379B2-F481-4062-BC60-A56EA857A811 Q30830619-E4D619C8-D347-4C54-9D3C-A896E83C081A Q33274194-0330A29C-C127-4A31-B825-247D03E4A22D Q33308246-3E8F9CDE-D2BB-42DB-A183-93CACCAFDB3C Q33310152-75ED5027-76D1-4EC9-954A-CCF55E79B03F Q33313878-32A73B86-6EC5-4E4F-9597-6636FC16CF62 Q33345905-DABB01D3-FC68-465C-AFAA-BF66A9C206BA Q33354070-208ECADB-8BCA-4740-AA75-DA7136DCACD8 Q33379075-520DCA1B-44DA-4C8E-A6FA-AB1AB83CF4DD Q33381538-5E52157D-B4FC-42B7-9633-29761CDAFCF7 Q33392723-5F6BDDD2-C54C-4B6D-B006-2EDFF08A0123 Q33399724-436A3056-4F5D-4D0A-BC4D-8A8FB77E9233 Q33402486-FE370267-BC67-4112-9CBF-6B3180668D95 Q33427803-287A3539-CED5-4AEA-AFFA-2A17DC1727EE Q33502755-3B7F7F89-5D3C-41CF-926F-27EFA422D4F0 Q33545560-8B6307A2-1373-445E-9D33-59D5CA59F692 Q33558348-0938606C-FF25-45D2-82C0-89A0B51260E1 Q33578049-A7DA8613-BA0C-471F-9E9B-71F372454014

P2860

Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.

Item

http://www.wikidata.org/entity/Q34468117

description

2003 nî lūn-bûn

@nan

2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu