Targeted disruption of the PDZK1 gene by homologous recombination. - Wikidata - wikimedia - TriplyDB

Targeted disruption of the PDZK1 gene by homologous recombination.

Targeted disruption of the PDZK1 gene by homologous recombination.

http://www.wikidata.org/entity/Q34472849

about

The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus Role of PDZK1 in membrane expression of renal brush border ion exchangers.Regulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factors In Vitro and in Vivo Analysis of the Binding of the C Terminus of the HDL Receptor Scavenger Receptor Class B, Type I (SR-BI), to the PDZ1 Domain of Its Adaptor Protein PDZK1 Identification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I Interactions of MAP17 with the NaPi-IIa/PDZK1 protein complex in renal proximal tubular cells Identification of small PDZK1-associated protein, DD96/MAP17, as a regulator of PDZK1 and plasma high density lipoprotein levels Targeted disruption of the PDZK1 gene in mice causes tissue-specific depletion of the high density lipoprotein receptor scavenger receptor class B type I and altered lipoprotein metabolism NHERF-1 binds to Mrp2 and regulates hepatic Mrp2 expression and function Loss of PDZK1 causes coronary artery occlusion and myocardial infarction in Paigen diet-fed apolipoprotein E deficient mice.Ovarian gene expression in the absence of FIGLA, an oocyte-specific transcription factor.Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.Carboxy-terminal deletion of the HDL receptor reduces receptor levels in liver and steroidogenic tissues, induces hypercholesterolemia, and causes fatal heart disease.Role of the adaptor protein PDZK1 in controlling the HDL receptor SR-BI Regulation of SR-BI protein levels by phosphorylation of its associated protein, PDZK1.NRFL-1, the C. elegans NHERF orthologue, interacts with amino acid transporter 6 (AAT-6) for age-dependent maintenance of AAT-6 on the membrane.Shank2 redistributes with NaPilla during regulated endocytosis Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface.Normal hepatic cell surface localization of the high density lipoprotein receptor, scavenger receptor class B, type I, depends on all four PDZ domains of PDZK1.D-AKAP2:PKA RII:PDZK1 ternary complex structure: insights from the nucleation of a polyvalent scaffold.Role of PDZK1 protein in apical membrane expression of renal sodium-coupled phosphate transporters.PDZK1 prevents neointima formation via suppression of breakpoint cluster region kinase in vascular smooth muscle.Drug Transporters and Na+/H+ Exchange Regulatory Factor PSD-95/Drosophila Discs Large/ZO-1 Proteins PDZ interactions and proximal tubular phosphate reabsorption.Regulation of ion transport by the NHERF family of PDZ proteins.NaPi-IIa and interacting partners.The role of NHERF-1 in the regulation of renal proximal tubule sodium-hydrogen exchanger 3 and sodium-dependent phosphate cotransporter 2a.Recent advances in renal phosphate transport.The emerging role of PDZ adapter proteins for regulation of intestinal ion transport.Influence of PDZK1 on lipoprotein metabolism and atherosclerosis.Monitoring protein-protein interactions between the mammalian integral membrane transporters and PDZ-interacting partners using a modified split-ubiquitin membrane yeast two-hybrid system Overexpression of the PDZ1 domain of PDZK1 blocks the activity of hepatic scavenger receptor, class B, type I by altering its abundance and cellular localization.Noncanonical role of the PDZ4 domain of the adaptor protein PDZK1 in the regulation of the hepatic high density lipoprotein receptor scavenger receptor class B, type I (SR-BI).Low-salt diet and cyclosporine nephrotoxicity: changes in kidney cell metabolism.The scaffold protein PDZK1 undergoes a head-to-tail intramolecular association that negatively regulates its interaction with EBP50.Na⁺/H⁺ exchanger regulatory factor 3 is critical for multidrug resistance protein 4-mediated drug efflux in the kidney.Differential association of the Na+/H+ Exchanger Regulatory Factor (NHERF) family of adaptor proteins with the raft- and the non-raft brush border membrane fractions of NHE3.Defective jejunal and colonic salt absorption and alteredNa(+)/H (+) exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice Human papillomavirus type 16 E6 and E7 oncoproteins act synergistically to cause head and neck cancer in mice.Distribution dynamics and functional importance of NHERF1 in regulation of Mrp-2 trafficking in hepatocytes.

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P2860

Targeted disruption of the PDZK1 gene by homologous recombination.

http://www.wikidata.org/entity/Q34472849

description

2003 nî lūn-bûn

@nan

2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Targeted disruption of the PDZK1 gene by homologous recombination.

@ast

Targeted disruption of the PDZK1 gene by homologous recombination.

@en

Targeted disruption of the PDZK1 gene by homologous recombination.

@nl

type

label

Targeted disruption of the PDZK1 gene by homologous recombination.

@ast

Targeted disruption of the PDZK1 gene by homologous recombination.

@en

Targeted disruption of the PDZK1 gene by homologous recombination.

@nl

prefLabel

Targeted disruption of the PDZK1 gene by homologous recombination.

@ast

Targeted disruption of the PDZK1 gene by homologous recombination.

@en

Targeted disruption of the PDZK1 gene by homologous recombination.

@nl

P1433

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P932

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P356

MCB.23.4.1175-1180.2003

P1433

Molecular and Cellular Biology

P1476

Targeted disruption of the PDZK1 gene by homologous recombination.

@en

P2093

Annalyn Gilchrist

http://www.w3.org/2001/XMLSchema#string

Christine Cirovic

http://www.w3.org/2001/XMLSchema#string

Mark Roberts

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Olivier Kocher

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Rinku Pal

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P2860

Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein

Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases

The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions

Identification and partial characterization of PDZK1: a novel protein containing PDZ interaction domains

Identification and partial characterization of a novel membrane-associated protein (MAP17) up-regulated in human carcinomas and modulating cell replication and tumor growth

Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ

The human testis determining factor SRY binds a nuclear factor containing PDZ protein interaction domains

Signaling through scaffold, anchoring, and adaptor proteins

Interaction of the type IIa Na/Pi cotransporter with PDZ proteins

PDZK1, a novel PDZ domain-containing protein up-regulated in carcinomas and mapped to chromosome 1q21, interacts with cMOAT (MRP2), the multidrug resistance-associated protein

P304

1175-1180

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scholarly article

P356

10.1128/MCB.23.4.1175-1180.2003

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P433

4

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23

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2003-02-01T00:00:00Z

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10927883

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12556478

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P932

141144

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