The G protein-gated potassium current I(K,ACh) is constitutively active in patients with chronic atrial fibrillation.
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NOS1AP modulates intracellular Ca(2+) in cardiac myocytes and is up-regulated in dystrophic cardiomyopathyNeuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and PitfallsIon Channels in the HeartCalcium dysregulation in atrial fibrillation: the role of CaMKIIEssential role of the m2R-RGS6-IKACh pathway in controlling intrinsic heart rate variabilityA Mathematical Model of Neonatal Rat Atrial Monolayers with Constitutively Active Acetylcholine-Mediated K+ CurrentEHRA/HRS/APHRS/SOLAECE expert consensus on Atrial cardiomyopathies: Definition, characterisation, and clinical implication.Constitutively Active Acetylcholine-Dependent Potassium Current Increases Atrial Defibrillation Threshold by Favoring Post-Shock Re-Initiation.Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1.G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.A real-time screening assay for GIRK1/4 channel blockers.HL-1 cells express an inwardly rectifying K+ current activated via muscarinic receptors comparable to that in mouse atrial myocytes.The inward rectifier current inhibitor PA-6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models.Effects of the novel amiodarone-like compound SAR114646A on cardiac ion channels and ventricular arrhythmias in rats.Targeting GIRK Channels for the Development of New Therapeutic Agents.Recent advances in the molecular pathophysiology of atrial fibrillation.Remodeling of atrial ATP-sensitive K⁺ channels in a model of salt-induced elevated blood pressure.Novel pharmacological targets for the rhythm control management of atrial fibrillation.Genetic defects in the hotspot of inwardly rectifying K(+) (Kir) channels and their metabolic consequences: a reviewPost-operative atrial fibrillation: a maze of mechanisms.Hypercholesterolemia induces up-regulation of KACh cardiac currents via a mechanism independent of phosphatidylinositol 4,5-bisphosphate and GβγAblation of sarcolipin results in atrial remodelingAtrial tachycardia induces remodelling of muscarinic receptors and their coupled potassium currents in canine left atrial and pulmonary vein cardiomyocytes.More types than one: multiple muscarinic receptor coupled K+ currents undergo remodelling in an experimental model of atrial fibrillationPolyunsaturated Fatty acids in atrial fibrillation: looking for the proper candidates.Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation.The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysisInnovative approaches to anti-arrhythmic drug therapy.Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation.Cardiac fibrillation: from ion channels to rotors in the human heartPathology-specific effects of the IKur/Ito/IK,ACh blocker AVE0118 on ion channels in human chronic atrial fibrillation.Regulation of the SK3 channel by microRNA-499--potential role in atrial fibrillation.Tissue-specific effects of acetylcholine in the canine heart.Isolation of human atrial myocytes for simultaneous measurements of Ca2+ transients and membrane currentsPleiotropic effects of antiarrhythmic agents: dronedarone in the treatment of atrial fibrillationRemodelling of cardiac repolarization: how homeostatic responses can lead to arrhythmogenesis.G-protein-coupled inward rectifier potassium current contributes to ventricular repolarizationAtrial-selective sodium channel block for the treatment of atrial fibrillation.Transient ST Elevation in Vagally Mediated Atrial Fibrillation.Altered Excitation-Contraction Coupling in Human Chronic Atrial Fibrillation.
P2860
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P2860
The G protein-gated potassium current I(K,ACh) is constitutively active in patients with chronic atrial fibrillation.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The G protein-gated potassium ...... h chronic atrial fibrillation.
@ast
The G protein-gated potassium ...... h chronic atrial fibrillation.
@en
The G protein-gated potassium ...... h chronic atrial fibrillation.
@nl
type
label
The G protein-gated potassium ...... h chronic atrial fibrillation.
@ast
The G protein-gated potassium ...... h chronic atrial fibrillation.
@en
The G protein-gated potassium ...... h chronic atrial fibrillation.
@nl
prefLabel
The G protein-gated potassium ...... h chronic atrial fibrillation.
@ast
The G protein-gated potassium ...... h chronic atrial fibrillation.
@en
The G protein-gated potassium ...... h chronic atrial fibrillation.
@nl
P2093
P1433
P1476
The G protein-gated potassium ...... h chronic atrial fibrillation.
@en
P2093
A Friedrich
P304
P356
10.1161/CIRCULATIONAHA.105.575332
P407
P577
2005-12-05T00:00:00Z