Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer. - Wikidata - wikimedia - TriplyDB

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.

http://www.wikidata.org/entity/Q35217426

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HIV Genome-Wide Protein Associations: a Review of 30 Years of Research Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes Generation and Characterization of a Bivalent HIV-1 Subtype C gp120 Protein Boost for Proof-of-Concept HIV Vaccine Efficacy Trials in Southern Africa HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers Survivors Remorse: antibody-mediated protection against HIV-1.Lessons learned from human HIV vaccine trials.A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure.HIV-1 Envelope Trimer Design and Immunization Strategies To Induce Broadly Neutralizing Antibodies.Spatial location of neutralizing and non-neutralizing B cell epitopes on domain 1 of ricin toxin's binding subunit The Broad Neutralizing Antibody Responses after HIV-1 Superinfection Are Not Dominated by Antibodies Directed to Epitopes Common in Single Infection Honing a harder-hitting hammerhead improves broadly neutralizing antibody breadth and potency Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity.Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity.Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.Differentiating founder and chronic HIV envelope sequences.Glycan-Dependent Neutralizing Antibodies Are Frequently Elicited in Individuals Chronically Infected with HIV-1 Clade B or C.Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer.Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody.Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability.Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency.Epitope-Independent Purification of Native-Like Envelope Trimers from Diverse HIV-1 Isolates.Molecular basis for epitope recognition by non-neutralizing anti-gp41 antibody F240 Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding.Natural infection as a blueprint for rational HIV vaccine design.Native-like Env trimers as a platform for HIV-1 vaccine design.Differential Antibody Responses to Conserved HIV-1 Neutralizing Epitopes in the Context of Multivalent Scaffolds and Native-Like gp140 Trimers.An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability.How to assess the binding strength of antibodies elicited by vaccination against HIV and other viruses.HIV-1 envelope glycoprotein immunogens to induce broadly neutralizing antibodies.Towards functional antibody-based vaccines to prevent pre-erythrocytic malaria infection.Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer Hidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer.Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers.Structure-based Design of Cyclically Permuted HIV-1 gp120 Trimers That Elicit Neutralizing Antibodies.

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P2860

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.

http://www.wikidata.org/entity/Q35217426

description

2015 nî lūn-bûn

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2015 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի մարտին հրատարակված գիտական հոդված

@hy

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.

@ast

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.

@en

type

label

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.

@ast

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.

@en

prefLabel

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.

@ast

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.

@en

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JOURNAL.PPAT.1004767

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Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.

@en

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Albert Cupo

http://www.w3.org/2001/XMLSchema#string

Andrew B Ward

http://www.w3.org/2001/XMLSchema#string

Anila Yasmeen

http://www.w3.org/2001/XMLSchema#string

Dennis R Burton

http://www.w3.org/2001/XMLSchema#string

Gabriel Ozorowski

http://www.w3.org/2001/XMLSchema#string

John P Moore

http://www.w3.org/2001/XMLSchema#string

Jonathan L Torres

http://www.w3.org/2001/XMLSchema#string

Kwinten Sliepen

http://www.w3.org/2001/XMLSchema#string

Mark Connors

http://www.w3.org/2001/XMLSchema#string

Per-Johan Klasse

http://www.w3.org/2001/XMLSchema#string

P2860

Structural mechanism of trimeric HIV-1 envelope glycoprotein activation

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

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e1004767

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scholarly article

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10.1371/JOURNAL.PPAT.1004767

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3

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11

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Jean-Philippe Julien

Ian Andrew Wilson

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2015-03-25T00:00:00Z

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274090732

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25807248

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4373910

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