The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins
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The virion host shutoff protein (UL41) of herpes simplex virus 1 is an endoribonuclease with a substrate specificity similar to that of RNase AMaturation and vesicle-mediated egress of primate gammaherpesvirus rhesus monkey rhadinovirus require inner tegument protein ORF52.Structure and capsid association of the herpesvirus large tegument protein UL36.Time-dependent transformation of the herpesvirus tegument.Comprehensive classification of the PIN domain-like superfamilyCoordinated destruction of cellular messages in translation complexes by the gammaherpesvirus host shutoff factor and the mammalian exonuclease Xrn1.Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNaseHerpes simplex virus 1 precludes replenishment of the short-lived receptor of tumor necrosis factor alpha by virion host shutoff-dependent degradation of its mRNA.Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradationProteomic characterization of pseudorabies virus extracellular virionsHerpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 geneGreen tea increases anti-inflammatory tristetraprolin and decreases pro-inflammatory tumor necrosis factor mRNA levels in rats.Vaccinia virus D10 protein has mRNA decapping activity, providing a mechanism for control of host and viral gene expression.Attenuation of herpes simplex virus neurovirulence with picornavirus cis-acting genetic elements.Packaging of the virion host shutoff (Vhs) protein of herpes simplex virus: two forms of the Vhs polypeptide are associated with intranuclear B and C capsids, but only one is associated with enveloped virionsTristetraprolin Recruits the Herpes Simplex Virion Host Shutoff RNase to AU-Rich Elements in Stress Response mRNAs To Enable Their Cleavage.Host shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion.Interaction of herpes simplex virus RNase with VP16 and VP22 is required for the accumulation of the protein but not for accumulation of mRNAMammalian alphaherpesvirus miRNAs.Replication-competent herpes simplex virus 1 isolates selected from cells transfected with a bacterial artificial chromosome DNA lacking only the UL49 gene vary with respect to the defect in the UL41 gene encoding host shutoff RNase.Corneal replication is an interferon response-independent bottleneck for virulence of herpes simplex virus 1 in the absence of virion host shutoff.Deletion of the herpes simplex virus 1 UL49 gene results in mRNA and protein translation defects that are complemented by secondary mutations in UL41.Roles of nucleic acid substrates and cofactors in the vhs protein activity of pseudorabies virus.αvβ3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1.Translocation and colocalization of ICP4 and ICP0 in cells infected with herpes simplex virus 1 mutants lacking glycoprotein E, glycoprotein I, or the virion host shutoff product of the UL41 gene.Selective ablation of virion host shutoff protein RNase activity attenuates herpes simplex virus 2 in mice.mRNA decay during herpes simplex virus (HSV) infections: mutations that affect translation of an mRNA influence the sites at which it is cleaved by the HSV virion host shutoff (Vhs) protein.Expression of gamma interferon-dependent genes is blocked independently by virion host shutoff RNase and by US3 protein kinaseHerpesvirus interference with major histocompatibility complex class II-restricted T-cell activation.Small interfering RNAs that deplete the cellular translation factor eIF4H impede mRNA degradation by the virion host shutoff protein of herpes simplex virusSelective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein.Cellular responses to HSV-1 infection are linked to specific types of alterations in the host transcriptome.Functional prediction of differentially expressed lncRNAs in HSV-1 infected human foreskin fibroblasts.Engagement of the lysine-specific demethylase/HDAC1/CoREST/REST complex by herpes simplex virus 1.Herpes simplex virus type 1 suppresses RNA-induced gene silencing in mammalian cells.The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomesThe nuclear-cytoplasmic shuttling of virion host shutoff RNase is enabled by pUL47 and an embedded nuclear export signal and defines the sites of degradation of AU-rich and stable cellular mRNAsPredicted poxvirus FEN1-like nuclease required for homologous recombination, double-strand break repair and full-size genome formation.A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein.Herpesviruses placating the unwilling host: manipulation of the MHC class II antigen presentation pathway.
P2860
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P2860
The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The U(L)41 protein of herpes s ...... her cellular or viral proteins
@ast
The U(L)41 protein of herpes s ...... her cellular or viral proteins
@en
type
label
The U(L)41 protein of herpes s ...... her cellular or viral proteins
@ast
The U(L)41 protein of herpes s ...... her cellular or viral proteins
@en
prefLabel
The U(L)41 protein of herpes s ...... her cellular or viral proteins
@ast
The U(L)41 protein of herpes s ...... her cellular or viral proteins
@en
P2860
P356
P1476
The U(L)41 protein of herpes s ...... her cellular or viral proteins
@en
P2093
Weiran Zhang
P2860
P304
P356
10.1073/PNAS.0510712103
P407
P577
2006-02-13T00:00:00Z