Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys. - Wikidata - wikimedia - TriplyDB

Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys.

Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys.

http://www.wikidata.org/entity/Q34480315

about

Genetic manipulation in pigs Use of genetically-engineered pig donors in islet transplantation Kidney xenotransplantation Immunogenicity in xenogeneic scaffold generation: antigen removal vs. decellularization Decellularized matrices for cardiovascular tissue engineering Anti-Gal: an abundant human natural antibody of multiple pathogeneses and clinical benefits Clinical xenotransplantation of organs: why aren't we there yet?Gene expression and pathway analysis of effects of the CMAH deactivation on mouse lung, kidney and heart.The Galalpha1,3Galbeta1,4GlcNAc-R (alpha-Gal) epitope: a carbohydrate of unique evolution and clinical relevance Use of molecular modeling and site-directed mutagenesis to define the structural basis for the immune response to carbohydrate xenoantigens.Identification of an anti-idiotypic antibody that defines a B-cell subset(s) producing xenoantibodies in primates.Coagulation dysregulation as a barrier to xenotransplantation in the primate A snapshot of CNVs in the pig genome Pathologic characteristics of transplanted kidney xenografts.Immunobiology of liver xenotransplantation.Pig-to-baboon heterotopic heart transplantation--exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade-based regimens.Identification of alpha-Gal and non-Gal epitopes in pig corneal endothelial cells and keratocytes by using mass spectrometry.Results of gal-knockout porcine thymokidney xenografts.Rejection of cardiac xenografts transplanted from alpha1,3-galactosyltransferase gene-knockout (GalT-KO) pigs to baboons.Overcoming the barriers to xenotransplantation: prospects for the future A novel and effective method to generate human porcine-specific regulatory T cells with high expression of IL-10, TGF-β1 and IL-35 Current status of xenotransplantation and prospects for clinical application Porcine Knock-in Fibroblasts Expressing hDAF on α-1,3-Galactosyltransferase (GGTA1) Gene Locus.Xenoantigenicity of porcine decellularized valves Double knockout pigs deficient in N-glycolylneuraminic acid and galactose α-1,3-galactose reduce the humoral barrier to xenotransplantation.Reduced binding of human antibodies to cells from GGTA1/CMAH KO pigs.Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/β4GalNT2 genes The role of genetically engineered pigs in xenotransplantation research.Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft The innate immune response and activation of coagulation in alpha1,3-galactosyltransferase gene-knockout xenograft recipients Double transgenic pigs with combined expression of human α1,2-fucosyltransferase and α-galactosidase designed to avoid hyperacute xenograft rejection Identification of human preformed antibody targets in GTKO pigs.Results of life-supporting galactosyltransferase knockout kidneys in cynomolgus monkeys using two different sources of galactosyltransferase knockout Swine Progress in pig-to-non-human primate transplantation models (1998-2013): a comprehensive review of the literature N-linked glycan profiling of GGTA1/CMAH knockout pigs identifies new potential carbohydrate xenoantigens.Bortezomib, C1-inhibitor and plasma exchange do not prolong the survival of multi-transgenic GalT-KO pig kidney xenografts in baboons Putative porcine embryonic stem cell lines derived from aggregated four-celled cloned embryos produced by oocyte bisection cloning Erythrocytes from GGTA1/CMAH knockout pigs: implications for xenotransfusion and testing in non-human primates.Initial in vivo experience of pig artery patch transplantation in baboons using mutant MHC (CIITA-DN) pigs High incidence of xenogenic bone marrow engraftment in pig-to-baboon intra-bone bone marrow transplantation

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P2860

Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys.

http://www.wikidata.org/entity/Q34480315

description

2005 nî lūn-bûn

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2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Acute rejection is associated ...... sing Gal-knockout pig kidneys.

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Acute rejection is associated ...... sing Gal-knockout pig kidneys.

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Acute rejection is associated ...... sing Gal-knockout pig kidneys.

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type

label

Acute rejection is associated ...... sing Gal-knockout pig kidneys.

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Acute rejection is associated ...... sing Gal-knockout pig kidneys.

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Acute rejection is associated ...... sing Gal-knockout pig kidneys.

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Acute rejection is associated ...... sing Gal-knockout pig kidneys.

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Acute rejection is associated ...... sing Gal-knockout pig kidneys.

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Acute rejection is associated ...... sing Gal-knockout pig kidneys.

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Nature Medicine

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Acute rejection is associated ...... sing Gal-knockout pig kidneys.

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Anthony Jevnikar

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Bertha Garcia

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David J White

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David K C Cooper

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Gang Chen

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Hongtao Sun

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Hua Qian

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Laura Copeman

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Noriko Murase

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Robert Zhong

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P2860

Human natural anti-alpha-galactosyl IgG. II. The specific recognition of alpha (1----3)-linked galactose residues

Production of alpha 1,3-galactosyltransferase-deficient pigs.

Clinical trials: where are we now?

The role of anti-Galalpha1-3Gal antibodies in acute vascular rejection and accommodation of xenografts.

Removal of anti-porcine natural antibodies from human and nonhuman primate plasma in vitro and in vivo by a Galalpha1-3Galbeta1-4betaGlc-X immunoaffinity column.

Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning.

Tolerogenic immunosuppression for organ transplantation

Identification of alpha-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in man.

Carbohydrate antigens of pig tissues reacting with human natural antibodies as potential targets for hyperacute vascular rejection in pig-to-man organ xenotransplantation.

Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue.

P2888

P304

1295-1298

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10.1038/NM1330

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12

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11

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Thomas E. Starzl

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2005-11-27T00:00:00Z

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7456577

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16311604

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3018862

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